Creatine supplementation during college football training does not increase the incidence of cramping or injury

Greenwood, Michael; Kreider, Richard B.; Melton, Charlie; Rasmussen, Christopher; Lancaster, Stacy; Cantler, E.; Milnor, P.; Almada, Anthony L.

doi:10.1007/978-1-4615-0247-0_12

Cited by 20 publications

(33 citation statements)

References 28 publications

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“…In conjunction with other previous studies (12,13), no clinically or statistically significant changes occurred relative to renal or hepatic function and markers of protein metabolism. Furthermore, the addition of D-pinitol to the creatine regimen was well tolerated and does not appear to invoke any negative health consequence from its use in healthy, resistance-training males, which is consistent with the available literature (5,6,14).…”

Section: Discussionsupporting

confidence: 54%

The Effects of Creatine Monohydrate Supplementation With and Without D-Pinitol on Resistance Training Adaptations

Kerksick

Wilborn²,

Campbell³

et al. 2009

Journal of Strength and Conditioning Research

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Coingestion of D-pinitol with creatine (CR) has been reported to enhance creatine uptake. The purpose of this study was to evaluate whether adding D-pinitol to CR affects training adaptations, body composition, whole-body creatine retention, and/or blood safety markers when compared to CR ingestion alone after 4 weeks of resistance training. Twenty-four resistance trained males were randomly assigned in a double-blind manner to creatine + pinitol (CRP) or creatine monohydrate (CR) prior to beginning a supervised 4-week resistance training program. Subjects ingested a typical loading phase (i.e., 20 g/d-1 for 5 days) before ingesting 5 g/d-1 the remaining 23 days. Performance measures were assessed at baseline (T0), week 1 (T1), and week 4 (T2) and included 1 repetition maximum (1RM) bench press (BP), 1RM leg press (LP), isokinetic knee extension, and a 30-second Wingate anaerobic capacity test. Fasting blood and body composition using dual-energy x-ray absorptiometry (DEXA) were determined at T1 and T3. Data were analyzed by repeated measures analysis of variance (ANOVA). Creatine retention increased (p < 0.001) in both groups as a result of supplementation but was not different between groups (p > 0.05). Significant improvements in upper- and lower-body strength and body composition occurred in both groups. However, significantly greater increases in lean mass and fat-free mass occurred in the CR group when compared to CRP (p <0.05). Adding D-pinitol to creatine monohydrate does not appear to facilitate further physiological adaptations while resistance training. Creatine monohydrate supplementation helps to improve strength and body composition while resistance training. Data from this study assist in determining the potential role the addition of D-pinitol to creatine may aid in facilitating training adaptations to exercise.

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Section: Discussionsupporting

confidence: 54%

The Effects of Creatine Monohydrate Supplementation With and Without D-Pinitol on Resistance Training Adaptations

Kerksick

Wilborn²,

Campbell³

et al. 2009

Journal of Strength and Conditioning Research

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“…Complaints of muscle pain and cramping were reported with various multicomponent dietary supplements containing creatine, amino acids (taurine, l-carnitine, glutamine, L-tyrosine, and L-arginine), Morinda Citrifolia (Noni), yohimbe, saw palmetto, caffeine, and Citrus aurantium. Creatine has been reported to cause muscle cramping and, rarely, rhabdomyolysis [12,13]; however, some recent clinical studies do not support this association [14,15]. Although definitive causality could not be established in our cases because of a lack of substantiating scientific evidence, the frequency of similar reports raises questions about possible muscle toxicity of some dietary supplements.…”

mentioning

confidence: 72%

Dietary supplement adverse events: Report of a one-year poison center surveillance project

et al. 2008

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“…While athletes who are taking CM may experience these symptoms, the scientific literature suggests that these athletes have no greater, and a possibly lower, risk of these symptoms than those not supplementing with CM [2,4,66,67]. …”

Section: Creatine Supplementation and Exercise: A Review Of The Litermentioning

confidence: 99%

International Society of Sports Nutrition position stand: creatine supplementation and exercise

Buford¹,

Kreider²,

Stout³

et al. 2007

Journal of the International Society of Sports Nutrition

226

229

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Creatine supplementation during college football training does not increase the incidence of cramping or injury

Cited by 20 publications

References 28 publications

The Effects of Creatine Monohydrate Supplementation With and Without D-Pinitol on Resistance Training Adaptations

The Effects of Creatine Monohydrate Supplementation With and Without D-Pinitol on Resistance Training Adaptations

Dietary supplement adverse events: Report of a one-year poison center surveillance project

International Society of Sports Nutrition position stand: creatine supplementation and exercise

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