Creatine kinase isoenzyme activities in men and women following a marathon race

Rogers, M. A.; Stull, G. Alan; Apple, Fred S.

doi:10.1249/00005768-198512000-00010

Cited by 66 publications

(32 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, serum CK activity fluctuations have been used to document changes in basal membrane permeability that accompany chronic, physiological states such as regular exercise training [35]. The present investigation demonstrates, for the first time, that exercise increases serum CK activity in regularly exercising women (fig.…”

Section: Discussionmentioning

confidence: 60%

Serum Creatine Kinase Activity Varies with Ovulatory Status in Regularly Exercising, Premenopausal Women

2006

View full text Add to dashboard Cite

Background/Aims: The clinical complications associated with an unopposed estrogen environment and luteal phase defects observed in exercising women prompted the examination of the relationship of exercise and endogenous ovarian steroids with serum creatine kinase (CK) activity. Methods: Subjects (n = 34) were classified into three groups according to their exercise and menstrual status, sedentary and exercising ovulatory groups (SedOvul, ExOvul), and an exercising amenorrheic group (ExAmen). Daily urine samples were collected to assess urinary ovarian steroid exposure and menstrual status. Serum CK activity was assayed in each menstrual cycle of all subjects. Results: Exercise increased serum CK activity in all exercising subjects (p < 0.01), but the increase was greater in amenorrheic women compared to ovulatory women (SedOvul: 33.0 ± 3.4; ExOvul: 43.7 ± 4.1; ExAmen: 54.4 ± 3.6, p < 0.05). When the ovulatory women were further divided into those with normal steroid production (ExOvul subgroup) and those with a suppressed progesterone luteal phase environment (ExLPD), both the ExOvul (51.9 ± 5.4 IU/l) subgroup and ExAmen group had higher serum CK activity (p < 0.05) than the ExLPD (36.6 ± 5.2 IU/l) subjects or the sedentary controls. Conclusions: These data demonstrate the complex association between ovarian hormone status and the normal serum CK response to regular mechanical stress imposed by chronic exercise training.

show abstract

Section: Discussionmentioning

confidence: 60%

Serum Creatine Kinase Activity Varies with Ovulatory Status in Regularly Exercising, Premenopausal Women

2006

View full text Add to dashboard Cite

show abstract

“…One of them discusses the variations in the recruiting of muscle fibers or the difference in muscle mass observed between men and women 28,29 . The role of the estrogen and its derivatives has also been implied in the CK levels reduction in women compared to men.…”

Section: Discussionmentioning

confidence: 99%

Infecção experimental pelo Trypanosoma cruzi em camundongos: influência do exercício físico versus linhagens e sexos

Soares

Franzói-de-Moraes

et al. 2012

Rev Bras Med Esporte

View full text Add to dashboard Cite

Background: Chagas disease is an infection caused by Trypanosoma cruzi that affects eight million people in Latin America. One factor linked to the lifestyle that significantly interferes in the response to infection is physical exercise, depending on the kind, intensity and frequency of the activity practiced. Objective: To evaluate the influence of pre-infection chronic moderate aerobic exercise in the development of experimental infection with T. cruzi in mice of two distinct lineages from both sexes. Methods: 30-day old Swiss and BALB/c mice (male and female) were divided into four groups for each strain and sex (total 16) and named as follows: SM (Swiss males), SF (Swiss females) BM (BALB/c mice) and BF (BALB/c mice). The groups were: NT NI (untrained uninfected) T NI (trained not infected); NT I (untrained infected), TI (trained infected). The aerobic exercise pre-moderate chronic infection training was performed with one daily session for eight weeks, five times a week. The inoculum was 1,400 blood trypomastigotes of Y strain of T. cruziintraperitoneally. The peak of parasites, parasitemia total and average measurements of the serum activities of CK and CK-MB were evaluated. Results and Conclusions: The physical training promoted reduction in peak, parasitemia parasites and total average in animals infected with T. cruzi in both strains and sexes. Physical training induced reduction in serum activities of CK and CK-MB in animals infected with T. cruzi of both sexes and from the two strains, except for females in the Swiss CK activity.

show abstract

“…CK exÎsts as three different isoenzymes that are specific to different types of tissue: CK-MM (found in skeletal muscle), CK-MB (found in cardiac and skeletal muscle) and CK-BB (found in brain) (Ebbeling & Clarkson, 1989). CK-MM is primarily responsible for the postexercise nse in plasma CK activity as it accounts for 90-100% of the total CK activity in skeletal muscle (Rogers et al, 1985).…”

Section: (221) Loss Of M D E F U N C T I O Nmentioning

confidence: 99%