Creatine kinase and creatine kinase MB in endurance runners and in patients with myocardial infarction

St�ubli, M.; Roessler, Bryan C.; K�chli, H. P.; Peheim, E.; Str�ub, P. W.

doi:10.1007/bf00943360

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“…The ratio of CK-MB to CK-MM after the marathon race ranged from 0.7% to 4.4% in the present study and was in other studies 3.3% to 9.2% (2), 1.7% to 11.3% (18), I %to 18%(42),upto lO.6%(28),8.3% 6.3%(4l), I %to 19% (26), and 3.4% 1.1 % (32). Stäubli et al (42) found also that the percentage of CK-MB in marathoners (4.3% to 6.6%) was different from that of patients with acute myocardial infarction (8.2%to 15%).…”

Section: Resultsmentioning

confidence: 92%

Indicators of Cell Breakdown in Plasma of Men During and After a Marathon Race

et al. 1988

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Plasma indicators of muscle cell leakage and of hemolysis were studied in 23 runners before and after a marathon race. Blood samples were drawn from an antecubital vein the morning before the race (baseline), at 3 p.m., i.e., 2 h before the start, on arrival, 12 and 36 h, and 7 days later. Compared with the baseline values, the plasma creatinine phosphokinase MM and MB subfractions, aldolase and glutamicoxaloacetic transaminase activity were increased immediately after the race, rose further 12 h after the marathon, and remained elevated the race, rose further 12 h after the marathon, and remained elevated 36 h and 7 days later. The plasma lactate dehydrogenase activity and myoglobin concentration were increased on arrival and returned to the pre-race activity 7 days after the marathon. Compared with the pre-race values, the plasma haptoglobin concentration was decreased immediately and 12 h after the marathon. Our data show that indicators of muscle cell leakage and of hemolysis in plasma, withdrawn after a marathon race, remained elevated for up to 7 days after the race.

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Section: Resultsmentioning

confidence: 92%