Creatine-electrolyte supplementation improves repeated sprint cycling performance: A double blind randomized control study

Crisafulli, Daniel L.; Buddhadev, Harsh H.; Brilla, L. R.; Chalmers, Gordon; Suprak, David N.; Juan, Jun G. San

doi:10.1186/s12970-018-0226-y

Cited by 23 publications

(19 citation statements)

References 65 publications

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“…For example, Wang et al (2018) reported that creatine supplementation combined with exercise training for 4 weeks improved maximal muscular strength and reduced exercise-associated muscle damage in adults. Furthermore, oral consumption of creatine electrolyte improved overall and repeated short duration sprint cycling performance (Crisafulli et al 2018), as well as anaerobic power and strength in athletes (Hummer et al 2019).…”

Section: Health Benefits Of Creatine Supplementationmentioning

confidence: 94%

Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health

2020

Amino Acids

298

192

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Taurine (a sulfur-containing β-amino acid), creatine (a metabolite of arginine, glycine and methionine), carnosine (a dipeptide; β-alanyl-l-histidine), and 4-hydroxyproline (an imino acid; also often referred to as an amino acid) were discovered in cattle, and the discovery of anserine (a methylated product of carnosine; β-alanyl-1-methyl-l-histidine) also originated with cattle. These five nutrients are highly abundant in beef, and have important physiological roles in anti-oxidative and antiinflammatory reactions, as well as neurological, muscular, retinal, immunological and cardiovascular function. Of particular note, taurine, carnosine, anserine, and creatine are absent from plants, and hydroxyproline is negligible in many plant-source foods. Consumption of 30 g dry beef can fully meet daily physiological needs of the healthy 70-kg adult human for taurine and carnosine, and can also provide large amounts of creatine, anserine and 4-hydroxyproline to improve human nutrition and health, including metabolic, retinal, immunological, muscular, cartilage, neurological, and cardiovascular health. The present review provides the public with the much-needed knowledge of nutritionally and physiologically significant amino acids, dipeptides and creatine in animal-source foods (including beef). Dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline are beneficial for preventing and treating obesity, cardiovascular dysfunction, and ageing-related disorders, as well as inhibiting tumorigenesis, improving skin and bone health, ameliorating neurological abnormalities, and promoting well being in infants, children and adults. Furthermore, these nutrients may promote the immunological defense of humans against infections by bacteria, fungi, parasites, and viruses (including coronavirus) through enhancing the metabolism and functions of monocytes, macrophages, and other cells of the immune system. Red meat (including beef) is a functional food for optimizing human growth, development and health.

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Section: Health Benefits Of Creatine Supplementationmentioning

confidence: 94%

Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health

2020

Amino Acids

298

192

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“…The sample size computation was based on the study by Flanagan and Jakeman [ 25 ]. Based on a statistical power analysis, a total sample size of 16 participants (8 per group) was needed to achieve a statistical power of 0.8 to detect a large effect size (ES) for supplement-time interaction at an alpha level of 0.05 [ 26 ]. The characteristics of the subjects are described in Table 1 .…”

Section: Methodsmentioning

confidence: 99%

Effects of 4-Week Creatine Supplementation Combined with Complex Training on Muscle Damage and Sport Performance

et al. 2018

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Creatine supplementation has an ergogenic effect in an acute complex training bout, but the benefits of chronic creatine supplementation during long-term complex training remain unknown. The study aimed to evaluate the effects of 4-week complex training combined with creatine supplementation on sport performances and muscle damage biomarkers. Thirty explosive athletes were assigned to the creatine or placebo group, which consumed 20 g of creatine or carboxymethyl cellulose, respectively, per day for 6 days followed by 2 g of the supplements until the end of the study. After 6 days of supplementation, subjects performed tests of one repetition maximum (1-RM) strength of half squat and complex training bouts to determine the optimal individual post-activation potentiation time. Thereafter, all subjects performed a complex training programme consisting of six sets of 5-RM half squats and plyometric jumps 3 times per week for 4 weeks. Body composition, 30-m sprint and jump performances were assessed before and after the training period. Moreover, blood creatine kinase (CK) activity was analysed at the first and the last training bout. After the training, the 1-RM strength in the creatine group was significantly greater than in the placebo group (p < 0.05). CK activity after the complex training bout in the creatine group was significantly reduced compared with the placebo group (p < 0.05). No differences were noted for other variables. This study concluded that creatine supplementation combined with complex training improved maximal muscular strength and reduced muscle damage during training.

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“…The first is the duration of the experiment, which lasted 16 weeks. Most previous studies with Cr supplementation lasted on the average from 5 to 7 days, up to a few weeks [ 17 , 21 , 24 , 35 ]. Conducting long-term supplementation research with soccer players or other contact sport disciplines is quite difficult, as such sports expose players to injuries, which in turn automatically exclude them from the research [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Soccer is among the sporting activities which are characterized by high-intensity actions, such as sprinting, jumping, kicking, tackling and changes of direction, interspersed by low-intensity jogging or walking [ 11 , 12 , 13 , 14 ]. Considering that at the elite level, players cover from 8 to 13 km during a game, the high level of aerobic fitness in soccer seems fully justified [ 15 , 16 , 17 ]. However, keeping in mind that players perform up to 250 high-intensity actions during a game, it is currently accepted that the decisive actions are covered by anaerobic metabolism [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

“…Over the last decades, there have been numerous studies evaluating the effects of Cr supplementation on physical performance in soccer, which give conflicting results [ 1 , 10 , 12 , 17 ]. Some authors confirm a positive influence of Cr supplementation [ 1 , 12 , 17 ], yet in most cases, only minor benefits were recorded [ 20 , 21 , 22 ]. Equivocal results of Cr supplementation have been observed when single action maximal performance was evaluated, such as in short sprints or jumping tests [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

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The Effects of Long-Term Magnesium Creatine Chelate Supplementation on Repeated Sprint Ability (RAST) in Elite Soccer Players

et al. 2020

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Aim: The aim of the study was to evaluate the effects of 16 weeks of a low dose of magnesium creatine chelate supplementation on repeated sprint ability test (RAST) results in elite soccer players. Materials: Twenty well-trained soccer players participated in the study. The players were divided randomly into two groups: the supplemented group (SG = 10) and placebo group (PG = 10). Out of the 20 subjects selected for the study, 16 (SG = 8, PG = 8) completed the entire experiment. The SG ingested a single dose of 5500 mg of magnesium creatine chelate (MgCr-C), in 4 capsules per day, which was 0.07 g/kg/d. The PG received an identical 4 capsules containing corn starch. Before and after the study, the RAST was performed. In the RAST, total time (TT), first and sixth 35 m sprint length (s), average power (AP) and max power (MP) were measured. Additionally, before and after the test, lactate LA (mmol/L) and acid–base equilibrium pH (-log(H+)), bicarbonates HCO3− (mmol/L) were evaluated. Also, in serum at rest, creatinine (mg/dL) concentration was measured. Results: After the study, significantly better results in TT, AP and MP were observed in the SG. No significant changes in the RAST results were observed in the PG. After the study, significant changes in the first 35 m sprint, as well as the sixth 35 m sprint results were registered in the SG, while insignificant changes occurred in the PG. A significantly higher creatinine concentration was observed. Also, a higher post-RAST concentration of LA, HCO3− and lower values of pH were observed in April, May and June compared with baseline values. Conclusions: The long timeframe, i.e., 16 weeks, of the low dose of magnesium creatine chelate supplementation improved the RAST results in the SG. Despite the long period of MgCr-C supplementation, in the end of the study, the creatinine level in the SG reached higher but still reference values.

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Creatine-electrolyte supplementation improves repeated sprint cycling performance: A double blind randomized control study

Cited by 23 publications

References 65 publications

Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health

Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health

Effects of 4-Week Creatine Supplementation Combined with Complex Training on Muscle Damage and Sport Performance

The Effects of Long-Term Magnesium Creatine Chelate Supplementation on Repeated Sprint Ability (RAST) in Elite Soccer Players

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