“…36 Another factor that contributes to bone resorption is the method of bone storage because freeze-dried bone loses its vitality and undergoes unpredictable resorption. 37 Relevant information about bone grafts, which ideally would be included in this manuscript but was not provided by the authors, includes the area of the cranium that required rehabilitation, graft type, 7,11,24,25,26,28,30,31,32,33 and area from which the donor graft was obtained. 7,11,24,26,28,30,31,32,33 Alloplastic materials, such as PMMA, are considered good choice for patients who require secondary reconstruction with a custom-made CAD/ CAM device following a previous failed cranioplasty (contour deformity caused by significant bone graft resorption or implant/bone graft removal resulting from infection).…”