Craniopharyngioma Classification

Pascual, José M.

doi:10.3171/jns.2008.109.12.1180

Cited by 72 publications

(70 citation statements)

References 8 publications

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“…Table 5 Ten-year overall survival, 10-year progression-free survival, functional capacity (percentiles for FMH ability score), and degree of obesity (BMI SDS (17) significantly the DOH, and CPs causing hydrocephalus are those occupying the third ventricle and expanding toward the Monro foramina. The lack of a significant relationship between the patterns of symptoms and the topography of the lesion in our study could be due to an inadequate topographical scheme of classification, which does not take into account the involvement of the third ventricle compartment or, alternatively, the primary infundibulotuberal development of the lesion (34,35,36,37,38). An accurate discrimination of vital structures such as the infundibulum, the third ventricle floor (tuber cinereum), the third ventricle cavity, and the type and degree of optic chiasm distortion (39) could not be performed due to missing imaging data not available in our retrospective multicenter study.…”

Section: Clinical Studymentioning

confidence: 50%

History before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis

Hoffmann

Boekhoff

Gebhardt

et al. 2015

European Journal of Endocrinology

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Objective: Childhood craniopharyngiomas (CP) are often diagnosed after a long duration of history (DOH). Tumor size, hypothalamic involvement (HI), and obesity are associated with reduced overall survival (OS) and functional capacity (FC). The effect of DOH and specific symptoms in history on presentation at initial diagnosis and long-term prognosis are unknown. Design: Retrospective analysis of patients' records and prospective longitudinal follow-up. Methods: Histories of 411 CP patients recruited in HIT Endo, KRANIOPHARYNGEOM 2000 were retrospectively evaluated for DOH, symptoms, and characteristics. The effect of specific manifestations and DOH on clinical presentation and tumor characteristics at time of initial CP diagnosis and long-term outcome were analyzed. Main outcome measures were 10-year OS and progression-free survival (PFS), FC, and BMI during longitudinal follow-up. Results: Median DOH was 6 months (range: 0.1-108 months) and correlated with age at diagnosis. Tumor size, HI, degree of resection, and BMI at diagnosis were not related to DOH. In multivariate analysis adjusted for age at diagnosis, only hydrocephalus was found to have a relevant influence on DOH. Visual and neurological deficits were associated with larger initial tumor size and impaired 10-year OS. Weight gain and growth failure were observed with longest DOH. PFS and FC were not related to any specific symptom. Endocrine deficits at diagnosis were associated with long DOH. Conclusions: CP is frequently diagnosed after long DOH, especially in older children. However, DOH was not associated with tumor size, HI, survival, or FC. Visual and neurological deficits necessitate rapid diagnostic workup.

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Section: Clinical Studymentioning

confidence: 50%

History before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis

Hoffmann

Boekhoff

Gebhardt

et al. 2015

European Journal of Endocrinology

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“…According to our systematic review of pathological, surgical, and MRI evidence for an accurate definition of CP-third ventricle relationships, CPs originating in the upper neurohypophysis (median eminence) and adjacent basal hypothalamus (tuber cinereum) correspond to the infundibulo-tuberal, or not strictly intraventricular, category-a group of lesions embedded within the hypothalamus itself. [16][17][18][19] In contrast, CPs originating in the pars tuberalis of the pituitary stalk, below an anatomically intact TVF, quite often push against the third ventricle, mimicking an intraventricular location. Hence, we included these seemingly intraventricular lesions in the suprasellar-pseudointraventricular category.…”

mentioning

confidence: 99%

“…Hence, we included these seemingly intraventricular lesions in the suprasellar-pseudointraventricular category. [16][17][18][19] From a surgical perspective, a precise distinction between both topographical categories is paramount.…”

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confidence: 99%

“…A tight band of adherence around the tumor accounts for the high rate of incomplete removals and recurrence associated with this subgroup of lesions. [16][17][18]26 Furthermore, radical surgery of recurrent infundibulo-tuberal CPs is associated with the highest risk of irreversible injury to the hypothalamus and long-term disabling sequelae, such as progressive obesity, reduced intellectual performance, and anomalous behavior.…”

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confidence: 99%

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Craniopharyngioma recurrence: the impact of tumor topography

Prieto

Castro-Dufourny

Carrasco

et al. 2016

JNS

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“…In addition, dermoid cysts tend to occur along the midline. 21,22 They are most commonly encountered in the posterior fossa cisterns, parasellar cisterns, and fourth ventricle. 10 Their occurrence inside the brain parenchyma is not commonly encountered.…”

Section: Discussionmentioning

confidence: 99%

Frontal dermoid cyst coexisting with suprasellar craniopharyngioma: a spectrum of ectodermally derived epithelial-lined cystic lesions?

Abou‐Al‐Shaar

Abd-El-Barr²,

Zaidi³

et al. 2016

FOC

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There is a wide group of lesions that may exist in the sellar and suprasellar regions. Embryologically, there is varying evidence that many of these entities may in fact represent a continuum of pathology deriving from a common ectodermal origin. The authors report a case of a concomitant suprasellar craniopharyngioma invading the third ventricle with a concurrent frontal lobe cystic dermoid tumor. A 21-year-old man presented to the authors' service with a 3-day history of worsening headache, nausea, vomiting, and blurry vision. Magnetic resonance imaging depicted a right frontal lobe lesion associated with a separate suprasellar cystic lesion invading the third ventricle. The patient underwent a right pterional craniotomy for resection of both lesions. Gross-total resection of the right frontal lesion was achieved, and subtotal resection of the suprasellar lesion was accomplished with some residual tumor adherent to the walls of the third ventricle. Histopathological examination of the resected right frontal lesion documented a diagnosis of dermoid cyst and, for the suprasellar lesion, a diagnosis of adamantinomatous craniopharyngioma. The occurrence of craniopharyngioma with dermoid cyst has not been reported in the literature before. Such an association might indeed suggest the previously reported hypothesis that these lesions represent a spectrum of ectodermally derived epithelial-lined cystic lesions.

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Craniopharyngioma Classification

Cited by 72 publications

References 8 publications

History before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis

History before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis

Craniopharyngioma recurrence: the impact of tumor topography

Frontal dermoid cyst coexisting with suprasellar craniopharyngioma: a spectrum of ectodermally derived epithelial-lined cystic lesions?

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