Craniofacial resection for tumors of the nasal cavity and paranasal sinuses—A 17-year experience

Lund, Valerie J.; Howard, David; Wei, William I.; Cheesman, A. D.

doi:10.1002/(sici)1097-0347(199803)20:2<97::aid-hed1>3.0.co;2-y

Cited by 184 publications

(131 citation statements)

References 42 publications

(30 reference statements)

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“…In ethmoid adenocarcinoma, despite the improvements in surgical and anesthetic techniques, survival data with CFR approach remain disappointing [1]. Our survival rates results confirm this suspicion with no great difference to other studies that currently perform CFR, whose overall survival rates at 5 and 10 years goes from 36% to 57% and 28% to 53%, respectively [7,[11][12][13][14][15]. Our good survival results also suggest that for well selected cases and with the appropriate use of adjuvant therapy, endoscopic resection of sinonasal cancer results in acceptable oncologic outcomes.…”

Section: Discussionmentioning

confidence: 99%

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Bernardo¹,

Ferreira²,

Silva³

et al. 2013

IJOHNS

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Introduction and Objectives: Sinonasal tumours represent only 3% of all head and neck cancers. Adenocarcinoma is the second most frequent histopathology type. Hardwood exposure has been considered a risk factor. Sinonasal adenocarcinoma grows silently which leads to a late diagnosis and low survival rates. The aim of this study was to present our experience in the management of the patients with sinonasal adenocarcinoma. Method: Retrospective medical records review of patients with sinonasal adenocarcinomas (1974 to 2009). Results: From 301 patients with sinonasal tumors, 67 had histology of adenocarcinoma. Patient average age was 60.1 ± 11.1 years (30 -84 years). 83.6% were man. 65.7% had history of working with wood. 70.1% of the patients had advance disease. The most common treatment strategy was external surgery (lateral rhinotomy (47.8%), sublabial (17.9%) or cranio-facial resection (6%)) or endoscopic approaches with postoperative radiotherapy. The 3 and 5 years overall survival rate were 60% and 49%, respectively. Conclusions: Our group study showed similar epidemiologic characteristics than other series. We confirmed sinonasal adenocarcinomas tendency to late diagnosis and wood dust exposure relation. In our experience, the limited surgical treatment (without craniofacial resection) and postoperative radiotherapy has good survival rates results, similar to other departments who consider the craniofacial resection as the standard treatment.

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Section: Discussionmentioning

confidence: 99%

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Bernardo¹,

Ferreira²,

Silva³

et al. 2013

IJOHNS

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“…Epithelial tumours represent over two/third of the SNC and, among them, the most common histotypes are adenocarcinoma and squamous cell carcinoma (SCC) (2) with European studies showing a frequency of adenocarcinoma (3)(4)(5) higher than that reported in the corresponding Northern American studies (6,7) . Other less common sinonasal epithelial histologies are adenoid cystic cancer (ACC) and undifferentiated carcinoma (SNUC).…”

Section: Introductionmentioning

confidence: 90%

Prevalence of occupational hazards in patients with different types of epithelial sinonasal cancers

Bonzini¹,

Batttaglia²,

Parassoni³

et al. 2013

Rhin

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SummaryBackground: Occupational exposure to carcinogens contributes greatly to the etiology of sinonasal cancer (SNC), but the role of different risk factors in determining different histological subtypes is disputed.Methodology: All consecutive surgical epithelial SNC cases (case-series study) underwent a systematic occupational medicine examination to determine previous exposure to a wide range of work-related chemical hazards. Results:We investigated 65 SNC cases including intestinal-type adenocarcinoma [ITAC] squamous-cell carcinoma [SCC], and others. Occupational exposure was recognized for 39 cases. Occupational exposures were sensibly more frequent among ITAC than among SCC or other histotypes. Occupational exposure in ITAC cases was to leather or wood dust only, while among non-ITAC cases, we recognised exposure to formaldehyde, solvents and metal fumes. A high proportion of SNC with occupational exposure originated in the ethmoidal epithelium. Conclusion:In our case-series of SNC, a very high frequency of previous occupational exposure to carcinogens was detected, suggesting that occupational hazards may be associated to the aetiopathogenesis, primarily for ITAC, but also for other histotypes. Besides leather or wood, other chemical agents must be recognized as occupational risk factors.

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“…A 5-year survival is 30%. 50,51 Adenocarcinoma is related to wood dust exposure. Treatment is surgical.…”

Section: Craniofacial Malignanciesmentioning

confidence: 99%