Cranio-Facial Fibrous Dysplasia: A case report of a conservative treatment in a monostotic form associated with an orthodontic management and a bone graft of the non-lytic bone area for dental implant rehabilitation

Abstract

How to cite this article: Seban A, Blein E, Perez S, Seban B. Cranio-Facial Fibrous Dysplasia: A case report of a conservative treatment in a monostotic form associated with an orthodontic management and a bone graft of the non-lytic bone area for dental implant rehabilitation. J Clin Adv Dent. 2019; 3: 018-022.

Fibrous Dysplasia: A Retrospective Review of Histologically Diagnosed Cases in a Tertiary Health Care Centre in Nigeria

“…Fibrous dysplasia is a benign medullary fibroosseous lesion in which normal bone is replaced by irregularly shaped immature bone and fibrous connective tissue [1][2][3][4]. This lesion can occur in the monostotic form with a solitary lesion affecting one bone or the polyostotic form with lesions affecting multiple bones [5][6][7].…”

“…An activating mutation in the cell surface G protein receptor which occurs postzygotically results in hyperactivity of the affected cells giving rise to fibrous dysplasia lesions [5][6][7][9][10][11]. Fibrous dysplasia is considered a congenital nonhereditary disease [1,9]. As many as 75% of patients with fibrous dysplasia present within the first three decades of life, however presentation is earlier for patients with the polyostotic form in which a majority present in the first decade [11][12].…”

“…The presenting signs/symptoms of fibrous dysplasia is dependent on the location and size of the lesion [1,5]. It can be asymptomatic and be detected during skeletal survey for an unrelated pathology [8,11].…”

“…Lesions of fibrous dysplasia usually appear as a replacement of the trabecular pattern of bone by a ground glass appearance on radiographs [11]. A definitive diagnosis usually requires a histopathological analysis due to the difficulty in differentiating it clinically and radiologically from some of its differential diagnosis especially in the craniofacial lesions [1]. Common differentials of fibrous dysplasia include Non-ossyfying fibroma, aneurysmal bone cyst, adamantinoma, giant cell tumour, low grade osteosarcoma and Paget's disease of bone [1,2,11,12].…”

“…A definitive diagnosis usually requires a histopathological analysis due to the difficulty in differentiating it clinically and radiologically from some of its differential diagnosis especially in the craniofacial lesions [1]. Common differentials of fibrous dysplasia include Non-ossyfying fibroma, aneurysmal bone cyst, adamantinoma, giant cell tumour, low grade osteosarcoma and Paget's disease of bone [1,2,11,12]. This study aims to analyze the age at diagnosis, sex, and site affected by fibrous dysplasia diagnosed in our health facility and to compare our findings to other published literature.…”