Cranial neuropathy associated with chlorinated solvents. Re: Facial nerve palsy after acute exposure to dichloromethane

Liss, Gary M.; House, Ron; Wills, Michael

doi:10.1002/ajim.20285

Cited by 2 publications

(1 citation statement)

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“…To our knowledge, this is the first report of hearing loss after DCM exposure. However, a case of reversible facial nerve palsy after acute exposure to DCM has been reported [Jacubovich et al, 2005] and several cases of trigeminal and peripheral nerve involvement after exposure to chlorinated solvents are described in the literature [Liss et al, 2006]. These reports suggest that organic solvents could have toxic effects on the peripheral nervous system, even after acute exposure.…”

Section: Discussionmentioning

confidence: 99%

Bilateral hearing loss after dichloromethane poisoning: A case report

Bonfiglioli

Carnevali

Lello

et al. 2013

American J Industrial Med

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Dichloromethane is a widely used organic solvent. Occupational exposure to dichloromethane is frequent and can result in both acute and chronic toxicity, affecting mostly the central nervous system, directly or through its metabolite, carbon monoxide. The effects of dichloromethane on the peripheral nervous system are debated. Here we report the case of a 37-year-old woman who was accidentally exposed to dichloromethane. In the days following the incident she experienced bilateral hypoacusis. Hearing loss regressed after 25 days treatment with hyperbaric oxygen. This is the first report of sudden hearing loss after acute exposure to dichloromethane, suggesting a possible toxic effect of this solvent on the auditory system.

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Section: Discussionmentioning

confidence: 99%