Cranberries vs Antibiotics to Prevent Urinary Tract Infections

Beerepoot, Mariëlle; Riet, Gerben ter; Nys, S.; Wal, Willem M. van der; Borgie, Corianne A. J. M. de; Reijke, Theo M. de; Prins, Jan M.; Koeijers, Jeanne; Verbon, Annelies; Stobberingh, Ellen E.; Geerlings, Suzanne E.

doi:10.1001/archinternmed.2011.306

Cited by 138 publications

(42 citation statements)

References 30 publications

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“…E. faecalis was found to be the most common in men and in patients aged over 60. However, women are equally prone to E. faecalis bacteriuria, according to Beerepoot et al [10,19]. They found that 16.5 % of urine samples from asymptomatic patients and 5.4 % of samples from symptomatic patients contained E. faecalis.…”

Section: Discussionmentioning

confidence: 99%

A comparison of monomicrobial versus polymicrobial Enterococcus faecalis bacteriuria in a French University Hospital

Fourcade

Canini

Lavigne

et al. 2015

Eur J Clin Microbiol Infect Dis

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Enterococci are of considerable relevance in the hospital setting. Their most common location is the urinary tract, where they may be responsible for both colonization and infections. They are often associated with the presence of other microorganisms. The aim was to compare monomicrobial and polymicrobial Enterococcus faecalis bacteriuria. A retrospective study was performed on the demographic, clinical, and laboratory data of 299 patients who had presented with E. faecalis bacteriuria in 2012 at a University Hospital. The bacteriuria was polymicrobial in 46.1 % of cases and in 36.4 % of cases was responsible for a urinary tract infection. Infections appeared to be more prevalent in the polymicrobial than the monomicrobial group (42 % vs 32 %, p = 0.06). Half of the patients who presented with urinary tract colonization received antibiotic treatment (54/ out of 10). A multivariate analysis adjusted for age (adjusted odds ratio [AOR] = 1.02 per year, p = 0.006), gender (AOR = 2.2, p = 0.007), and clinical classification (colonization or infection, AOR = 1.6, p = 0.091), showed that diabetes mellitus (AOR = 2.0, p = 0.04), hospital length of stay exceeding 28 days (AOR = 2.0, p = 0.03), and presence of a urinary catheter (AOR = 2.4, p = 0.001) were all factors associated with polymicrobial E. faecalis bacteriuria. A reduction in the length of hospital stay and the use of urinary catheters would appear to be required to decrease the incidence of urinary tract colonization and infections by polymicrobial E. faecalis. Improper use of antibiotics to treat urinary tract colonization remains a major concern.

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Section: Discussionmentioning

confidence: 99%

A comparison of monomicrobial versus polymicrobial Enterococcus faecalis bacteriuria in a French University Hospital

Fourcade

Canini

Lavigne

et al. 2015

Eur J Clin Microbiol Infect Dis

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“…In randomised trials comparing continuous co-trimoxazole (480mg daily) with cranberry extract12 and lactobacillus,13 resistance to co-trimoxazole, trimethoprim and amoxicillin in faeces and urine (measured by testing antibacterial sensitivity in the laboratory) had increased after 1 month of antibacterial use (from around 21–28% to around 73–91% in one trial;12 and from around 20–40% to around 80–95% in the other) 13. After 12 months' prophylactic therapy, resistance rates for ciprofloxacin and norfloxacin in urinary Escherichia coli isolates had also increased.…”

Section: Preventing Recurrent Infectionsmentioning

confidence: 99%

“…A more recent double-blind, double-dummy randomised placebo-controlled trial (involving 221 premenopausal women with recurrent UTIs) found that co-trimoxazole (480mg daily) was more effective than cranberry capsules (500mg twice daily) in preventing recurrent UTIs 12. After 12 months, the mean number of clinical recurrences was 1.8 (95% CI 0.8 to 2.7) with co-trimoxazole vs. 4.0 (95% CI 2.3 to 5.6) with cranberry, p = 0.02.…”

Section: Preventing Recurrent Infectionsmentioning

confidence: 99%

Prevention of recurrent urinary tract infections in women

2013

DTB

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Around 40-50% of women experience at least one urinary tract infection (UTI) during their lifetime and 20-30% of these have a recurrence within 3-4 months of the initial infection.¹ Recurrent UTI (usually defined as three episodes in the last 12 months or two episodes in the last 6 months) can have a considerable impact on a woman's quality of life. Each episode of acute UTI in young women is typically associated with about 6 days of symptoms, 2.4 days of restricted activities and 0.4 days of bed rest.¹ Antibacterial prophylaxis is effective in preventing recurrent episodes, but at the expense of unwanted effects and a risk of promoting bacterial resistance. Here we assess the efficacy of different antibacterial regimens and non-antibacterial alternatives (cranberry, probiotics, oestrogens, immunostimulation, hyaluronic acid and chondroitin, acupuncture and herbs) in the prevention of recurrent uncomplicated UTIs in women.

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“…In recent years Urinary tract infections are developing & are the second most common infection in the world [8]. Men are less than women involved to urinary tract infections, because; men have bigger urethra in their body [9]. UTI is a disease which, created in the woman or man and can transmitted it together (Venereal disease) [10].…”

Section: Introductionmentioning

confidence: 99%

The Antibacterial Effects of Zno Nanoparticles on Patients with Urinary Tract Infection Isolated From Alzahra Hospital in Isfahan, Iran

Torabi

2017

Zahedan J Res Med Sci

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Background: Urinary tract infection (UTI) is a kind of disease in kidneys that often caused by Escherichia coli bacteria, especially in women. Objectives: We studied the antibacterial effects of ZnO nanoparticles On patients with urinary tract infection that isolated from Alzahra hospital in Isfahan, Iran. It is hoped that by the research community's attention to this great problem of multi drug resistance E. coli treatment by ZnO NPs. Methods: In this experimental study, urine samples of multi drug resistance E. coli bacteria, Also colloidal ZnO nanoparticles prepared in size 20 nm, spherical shape and a concentration of 200 ppm were used .The methods of research were wells and disk agar diffusion in nutriant agar & LB medium and was evaluated antibacterial properties of the nanoparticles ,then incubated for 72 hours and the diameter of inhibitory zone of growth was measured, The data were analyzed by spss 16 version software. Results: The highest resistance of E. coli to antibiotics belongs to cefazolin and cefexime. The results showed that ZnO NPs in size 20 nm and spherical shape after 72 hours at 37°C can be used to treat Urinary infections caused by E. coli, it is recommended that further research considered the effects of different infections of Urinary tract infection in In vitro condition. Conclusions: Using ZnO nanoparticles with 20 nm diameters have acceptable antibacterial effect on Escherichia coli isolated from Urinary tract infection. The current study suggests that ZnO NPs could be a good candidate for an effective antibacterial agent against E. coli.

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Cranberries vs Antibiotics to Prevent Urinary Tract Infections

Abstract: isrctn.org Identifier: ISRCTN50717094.

Cited by 138 publications

References 30 publications

A comparison of monomicrobial versus polymicrobial Enterococcus faecalis bacteriuria in a French University Hospital

A comparison of monomicrobial versus polymicrobial Enterococcus faecalis bacteriuria in a French University Hospital

Prevention of recurrent urinary tract infections in women

The Antibacterial Effects of Zno Nanoparticles on Patients with Urinary Tract Infection Isolated From Alzahra Hospital in Isfahan, Iran

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