Coxiella burnetii (Q fever) in Rattus norvegicus and Rattus rattus at livestock farms and urban locations in the Netherlands; could Rattus spp. represent reservoirs for (re)introduction?

Reusken, Chantal; Plaats, Rozemarijn van der; Opsteegh, Marieke; Bruin, Arnout de; Swart, Arno

doi:10.1016/j.prevetmed.2011.05.003

Cited by 64 publications

(51 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Recent findings in Germany indicated regular sightings of wild rodents as risk factors for C. burnetii infection in humans, suggesting wild rodents as a direct source for human infection. 13 In this study, C. burnetii was identified by PCR in 18% of the rodents captured on Heixiazi Island at the Sino-Russian border, from April to October in 2011. However, it is difficult to compare these findings with those reported in other works, which present information on the presence of antibodies to C. burnetii in rodents.…”

Section: Discussionmentioning

confidence: 72%

“…However, it is difficult to compare these findings with those reported in other works, which present information on the presence of antibodies to C. burnetii in rodents. [13][14][15][16] The statistical results showed that weight was associated with C. burnetii infection, possibly because larger rodents become matured and move widely and have more chances to be infected with C. burnetii. The reason for the association between month of capture and C. burnetii infection may be the temperature differences between months.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Liu¹,

Xu²,

Fu³

et al. 2013

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. This work is a molecular epidemiologic study to detect the incidence of Coxiella burnetii in rodents on Heixiazi Island at the Sino-Russian border of Heilongjiang Province. Liver tissues were extracted and processed to test the incidence of C. burnetii infection using polymerase chain reaction analysis. In total, 18% (66 of 370) of rodents tested positive for infection. The results of logistic regression analysis indicated that infection with C. burnetii was associated significantly with weight and month of capture, and infection was found in all rodent species that were observed; there was no significant difference of sex on the infection of C. burnetii. Though phylogenetic analysis disclosed heterogeneity in the nucleotide sequences isolated from the island rodents, the majority of observed strains were among the most common strains found worldwide. This is the first report on the incidence of C. burnetii in rodents on Heixiazi Island at the Sino-Russian border.

show abstract

Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Liu¹,

Xu²,

Fu³

et al. 2013

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…L'ADN de C. burnetii a été détecté dans la rate de 4,9 % des rats bruns (Rattus norvegicus) et 3 % des rats noirs (Rattus rattus). Ce qui ne représente pas un risque fréquent de transmission, mais un maintien de l'agent pathogène dans les fermes (Reusken et al 2011). Les chiens et les chats peuvent aussi être infectés par C. burnetii et être associés avec des infections humaines dans les régions rurales et urbaines .…”

Section: Les Réservoirsunclassified

Coxiella burnetii, agent de la fièvre Q

Boarbi¹,

Frétin²,

Mori³

2016

Can. J. Microbiol.

View full text Add to dashboard Cite

Résumé : La fièvre Q est une zoonose de répartition mondiale excepté la Nouvelle-Zélande. Elle est due à une bactérie intracellulaire : Coxiella burnetii. Cette infection passe souvent inaperçue car la manifestation principale de la forme aiguë de la maladie est un syndrome pseudogrippal spontanément résolutif. C'est l'épidémie qui a eu lieu aux Pays-Bas qui a attiré l'attention sur cette maladie qui était moins étudiée auparavant. Cette synthèse résume la description de la bactérie (taxonomie, cycle intracellulaire et génomique) mais également la maladie (description, diagnostic, pathogénie et épidémiologie). Enfin, la vaccination de l'humain et des animaux est également analysée. Mots-clés : Coxiella burnetii, fièvre Q, épidémiologie, description, génomique.Abstract: Q fever is a zoonosis of worldwide distribution with the exception of New Zealand. It is caused by an intracellular bacterium, Coxiella burnetii. The disease often goes underdiagnosed because the main manifestation of its acute form is a general self-limiting flu-like syndrome. The Dutch epidemics renewed attention to this disease, which was less considered before. This review summarizes the description of C. burnetii (taxonomy, intracellular cycle, and genome) and Q fever disease (description, diagnosis, epidemiology, and pathogenesis). Finally, vaccination in humans and animals is also considered.

show abstract

“…W innych badaniach podkreślano związek pomiędzy występowaniem choroby a silnymi wiatrami, otwartą przestrzenią i znacznym zagęszczeniem zwierząt (12), a ponadto nie bez znaczenia mogły być także złe warunki chowu oraz kontakt ze ściółką zawierającą resztki popłodu lub poronione płody (19). Z danych piśmiennictwa z ostatnich lat wynika, że potencjalnym wektorem zarazka mogą być także szczury (14). W dwóch stadach bydła zastosowano szczepienie z wykorzystaniem zarejestrowanej w Polsce, inaktywowanej szczepionki Coxevac (CEVA), uzyskując poprawę wydajności mlecznej oraz obniżenie odsetka występowania przypadków urodzenia martwych noworodków, zatrzymania łożyska i zapalenia macicy.…”

unclassified

Epidemiological situation of Q fever in sheep, goats and cattle in the Wielkopolska Voivodeship between the years 2011 and 2015, based on monitoring studies and cases from clinical practice

Kneblewski

Budzyk²,

Szabłonski

et al. 2017

Medycyna Weterynaryjna

View full text Add to dashboard Cite

The publication presents the results of monitoring Q fever in the Wielkopolska Voivodeship and three outbreaks disclosed as part of a clinical field practice. In five years (2011 – 2015) of examination in the Wielkopolska Voivodeship, 2,431 serological tests were carried out (1,851 in sheep, 343 in goats and 237 in cattle). Antibodies against Coxiella burneti were found three times. The first positive result in 2011 affected herds of goats and cattle and was confirmed in the reference laboratory of the National Veterinary Research Institute in Pulawy. A specific DNA sequence for Coxiella burneti by real-time PCR method was found. The farm consisted of 1,494 goats and 397 cattle. Serological tests were carried out to give positive results in 15.3% of the cattle and 5.77% of the goats from the whole herd. Breeding selection and the elimination of seropositive animals and double oxytetracycline treatment reduced the proportion of animals with a positive result to 5.53% in cattle and 0.96% in goats. After more than a year the elimination of seropositive animals and probable natural decline in antibody levels has led to the recognition of an outbreak of Q fever to be eliminated. The second positive result of the monitoring of Q fever was found in 2014 in one cow out of seven respondents, but the serological test was not confirmed in the reference, as a specific DNA sequence for Coxiella burneti was not found. The research conducted in sheep in 2015 showed the presence of antibodies against Coxiella burneti in two samples. The results were confirmed by the detection of genetic material of the pathogen by real-time PCR examination in the National Veterinary Research Institute in Pulawy. Three outbreaks of Q fever revealed in clinical practice related to bovine herds where clinical disturbances were observed in: reproduction, milk production decrease or increase in internal body temperature and symptoms of the respiratory system. The positive ELISA test results were the reason for the elimination of seropositive animals. Moreover, after the disclosure of infection two herds were vaccinated using an inactivated vaccine Coxevac (CEVA), which caused the improvement of production results and relief of clinical symptoms. It is worth mentioning that in two farms along with cattle there were fallow deer supported by staff cowman. Official monitoring tests of Q fever revealed an outbreak of the disease in a herd of goats and cattle, which lead to taking effective action to protect public health because of the zoonotic nature of this infection and epidemiological risk. In the disclosure of these clinical signs in cattle it is advisable to carry out laboratory tests for Q fever.

show abstract

Coxiella burnetii (Q fever) in Rattus norvegicus and Rattus rattus at livestock farms and urban locations in the Netherlands; could Rattus spp. represent reservoirs for (re)introduction?

Cited by 64 publications

References 17 publications

Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Coxiella burnetii in Rodents on Heixiazi Island at the Sino-Russian Border

Coxiella burnetii, agent de la fièvre Q

Epidemiological situation of Q fever in sheep, goats and cattle in the Wielkopolska Voivodeship between the years 2011 and 2015, based on monitoring studies and cases from clinical practice

Contact Info

Product

Resources

About