Cow milk yield and composition before development of Escherichia coli mastitis

Jones, TO; Jones, PC

doi:10.1136/vr.119.13.319

Cited by 3 publications

(2 citation statements)

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“…Interestingly, the prechallenge milk production of these cows was higher than that of the other cows. According to Jones and Jones (1986), high milk yield may be a predisposing factor to E. coli mastitis; in the four herds studied, the yield of cows subsequently developing coliform mastitis was higher than that of control cows. Vandeputte‐van Messon et al .…”

Section: Discussionmentioning

confidence: 95%

Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally inducedEscherichia colimastitis

Rantala¹,

Kaartinen²,

Välimäki³

et al. 2002

Vet Pharm & Therapeutics

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The efficacy of flunixin alone and together with enrofloxacin in treatment of experimental Escherichia coli mastitis was compared using six cows. The cross-over study design was used. Pharmacokinetics of flunixin and enrofloxacin were also studied in these diseased cows. The response of each cow was similar after the first and second challenge and the individual reaction seemed to explain the severity of clinical signs. The most important predictive factor for outcome of E. coli mastitis was a heavy drop in milk yield. Treatment with enrofloxacin and flunixin enhanced elimination of bacteria, but the difference from those receiving flunixin alone was not significant. Two cows, which had received no antimicrobial treatment (Group 1), were killed on day 4 postchallenge. One cow was killed after the first and the other after the second challenge. Cows receiving combination therapy produced 0.9 L more milk per day during the study period than cows which had only received flunixin (P < 0.05). Based on our findings, antimicrobial treatment might be beneficial in the treatment of high-yielding cows in early lactation. The absorption of enrofloxacin was delayed after subcutaneous administration, the mean apparent elimination half-life being about 23 h, whereas after i.v. administration elimination t(1/2) was only 1.5 h. The majority of the antimicrobial activity in milk originated from the active metabolite, ciprofloxacin, which could be measured throughout the 120-h follow-up period after the last subcutaneous administration. No differences were present in the pharmacokinetic parameters of flunixin between treatment groups: mean elimination half-life was 5.7-6.2 h, volume of distribution 0.43-0.49 L/kg and clearance 0.13-0.14 L h/kg. No flunixin or merely traces were detected in milk: one of the three cows had a concentration of 0.019 mg/L 8 h after administration.

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Section: Discussionmentioning

confidence: 95%

Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally inducedEscherichia colimastitis

Rantala¹,

Kaartinen²,

Välimäki³

et al. 2002

Vet Pharm & Therapeutics

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show abstract

“…Variation in protein and lactose content of various districts may be due to different managemental practices adopted by farmers as well as environmental and health condition of animal is other factor which affecting milk composition. According to Jones and Jones (1986) low milk fat and low milk protein were considered as possible predisposing factors to bovine Escherichia coli mastitis.…”

Section: Milk Protein and Lactose Contentmentioning

confidence: 99%

Raw Milk Composition of Crossbred Cows and Correlation Between Milk Constituents in Selected Districts of Chhattisgarh, India

Chandrakar¹,

Kumar²,

Shakya³

et al. 2017

IJBSM

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The present study was carried out in four districts of Chhttisgarh to determine the quality of raw milk in this region. A total of 92 milk sample from crossbred cattle was collected and analysied for physico-chemical properties. The ANOVA analysis revealed that there is a significant difference (p<0.05) in all physico-chemical parameters among the districts, difference was non-significant in case of lactose percentage and Density. The overall mean percentages of fat, solid non-fat (SNF) and protein obtained were 3.812±0.043, 8.444±0.048 and 3.412±0.036 in that order. Durg districts recorded highest fat and snf content in comparisons to other district of study. In this study, highly significant (p<0.01) positive correlation was observed between fat and SNF (0.792), fat and protein (0.330) and fat and lactose (0.482). Correlation between SNF with protein (0.333) and lactose (0.345) were found to be positive and highly significant (p<0.01).Density showing non-significant correlation with all the milk constituent parameters. Efforts should be taken to change nutritionand management aspects in such a manner that quality parameter of milk is improved.Values of genetic correlations between productions have huge importance in selection of cows, as they provide possibility for selection of heads on more traits at the same time.

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Mastitis in Dairy Cows with Special Reference to Direct and Indirect Effects of Climatological Factors

Grommers¹

1987

Energy Metabolism in Farm Animals

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Cow milk yield and composition before development of Escherichia coli mastitis

Cited by 3 publications

References 0 publications

Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally inducedEscherichia colimastitis

Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally inducedEscherichia colimastitis

Raw Milk Composition of Crossbred Cows and Correlation Between Milk Constituents in Selected Districts of Chhattisgarh, India

Mastitis in Dairy Cows with Special Reference to Direct and Indirect Effects of Climatological Factors

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