COVID19 and acute lymphoblastic leukemias of children and adolescents: Updated recommendations (Version 2) of the Leukemia Committee of the French Society for the fight against Cancers and leukemias in children and adolescents (SFCE)

Cribado de SARS-CoV-2 en pacientes pediátricos con cáncer previo a hospitalización para infusión de quimioterapia

“…Los pacientes asintomáticos son una fuente potencial de infección. Varias publicaciones [7][8][9][10] coinciden en que el cribado mediante pruebas por RT-PCR para SARS-CoV-2 permite una detección temprana y eficaz para reducir la transmisión viral.…”

“…1 Varias guías recomiendan el cribado de los pacientes en tratamiento con quimioterapia para permitir la identificación temprana y el aislamiento de los pacientes asintomáticos. [7][8][9][10] H a s t a e l m o m e n t o , s e d i s p o n e d e p o c a información con respecto a la continuidad o la modificación del tratamiento quimioterápico en los niños asintomáticos con prueba positiva. 11 En el Hospital Garrahan, una de las estrategias implementadas fue la incorporación de un programa de cribado para detectar al paciente con enfermedad por el coronavirus del 2019 (COVID-19, por su sigla en inglés) asintomática previa a la internación para recibir los ciclos de quimioterapias o tratamiento hematológico parenteral.…”

SARS-CoV-2 screening in pediatric cancer patients before hospitalization for chemotherapy infusion

“…Asymptomatic patients are a potential source of infection. Several articles [7][8][9][10] agree that RT-PCR screening for SARS-CoV-2 allows for an early and effective detection in order to reduce viral dissemination.…”

“…1 Several guidelines recommend screening patients receiving chemotherapy for the early detection and isolation of asymptomatic patients. [7][8][9][10] To date, there is little information about the continuation or modification of chemotherapy in asymptomatic children with a positive test. 11 One of the strategies implemented at Hospital Garrahan was introducing a screening p r o g r a m f o r a s y m p t o m a t i c c o r o n a v i r u s disease 2019 (COVID-19) prior to hospitalization for chemotherapy courses or parenteral hematological treatment.…”

The COVID-19 pandemic in children and young people during 2020-2021: Learning about clinical presentation, patterns of spread, viral load, diagnosis and treatment

“…A study of 1490 immunocompromised children, defined as those requiring an annual influenza vaccination due to their underlying condition or medication, showed that their shielding worked very well during the pandemic in the UK because no one tested positive for SARS-CooV-2 [ 121 ]. In France, the Leukemia Committee of the French Society for the fight against Cancers and Leukemias in Children and Adolescents (SFCE) proposed specific recommendations, in absence of understanding of the risk that COVID-19 poses in these children that would emerge from clinical studies [ 122 ]. The paucity of data was also highlighted for pediatric solid organ transplant (SOT) recipients, with uncertainty over both the SARS-CoV-2 infection and the vaccination in terms of safety, immunogenicity, and vaccine efficacy.…”