COVID-19 ve Böbrek

Abstract

The coronavirus disease , caused by severe acute respiratory syndrome (ARDS) new type of coronavirus (SARS-CoV-2), is a serious public health emergency that has become a pandemic all over the world. Although initially identified as a respiratory targeted virus, the SARS-CoV-2 has now been shown to have multi-organ involvement other than lung involvement. Renal dysfunction (eGFR <60 ml/ min/1.73 m2) and proteinuria and microscopic hematuria in around 40% were detected in >30% of COVID-19 patients at hospitalization. In postmortem studies, the virus was isolated in different structures of the kidney. It has been shown histopathologically that the COVID-19 may cause acute kidney injury (AKI), acute tubular injury, acute glomerular injury and thrombotic microangiopathy as kidney involvement. In the first months of the pandemic, the incidence of COVID-19-related kidney complications was reported to be extremely low. However, large-scale studies on kidney involvement in the later months of the pandemic have shown the opposite. The most important risk factors