COVID-19 vaccine adverse reactions bring patients to emergency departments

Fertel, Baruch S.; Milk, Jason; Simon, Erin L.; Muir, McKinsey R.; Smalley, Courtney M.

doi:10.1016/j.ajem.2021.05.013

Cited by 5 publications

(4 citation statements)

References 2 publications

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“…ED overcrowding has long been a major issue, and many studies have investigated the causes and improvement strategies [ 26 , 27 ]. The increasing number of COVID-19 or COVID-19 post-vaccination patients visiting the ED has worsened overcrowding in the ED during the COVID-19 pandemic [ 28 , 29 , 30 ] As per the results of this study, non-enhanced brain CT does not need to be performed if there are no obvious neurological abnormalities in patients who visit the ED after vaccination.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Non-Enhanced Brain Computed Tomography in Patients Presenting to the Emergency Department with Headache after COVID-19 Vaccination

Lee

Kim

Paek

et al. 2023

JCM

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Headaches are a common side effect of vaccination against the severe acute respiratory syndrome, coronavirus 2; however, it is usually not necessary to seek emergency medical attention or undergo brain imaging such as non-enhanced brain computed tomography (CT) for routine evaluation of vaccine-related headaches. This study aimed to demonstrate that brain CT is of no clinical benefit to patients presenting to the emergency department (ED) with post-coronavirus disease 2019 (COVID-19) vaccination headaches. This retrospective, single-center observational study used electronic medical record (EMR) data of patients who received the COVID-19 vaccination during the first year of the vaccination program. In total, 914 patients were analyzed, of whom 435 underwent CT (CT group, n = 435; no CT group, n = 475). More female patients visited the ED, and there was no significant sex difference between the CT and no-CT groups. The type of vaccine affected the clinical decision to perform brain CT, but the number of doses did not. The CT rate was relatively high for patients who had received the ChAdOx1 nCoV-19 (Oxford–AstraZeneca) and Johnson and Johnson Janssen (Jansen) vaccines (p = 0.004). Focal neurological deficits were present in all cases of abnormalities on non-enhanced brain CT in patients complaining of headaches. Two out of the 435 patients had abnormal brain CT findings (glioblastoma and Rathke’s pouch cyst) at 35 and 32 days after vaccination, respectively. Non-enhanced brain CT should be performed cautiously in patients visiting the ED for post-vaccination headaches only.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Non-Enhanced Brain Computed Tomography in Patients Presenting to the Emergency Department with Headache after COVID-19 Vaccination

Lee

Kim

Paek

et al. 2023

JCM

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“…They also reported that 70.3% of the patients had a blood test, intravenous (IV) drugs were given to 61.6% of the patients, 45.8% of the patients had a chest X-ray, 20.3% of the patients had a thorax computed tomography, 81% of the patients were discharged, and 17.9% of the patients were hospitalized. The first three main complaints during admission were dyspnea, chest pain, and allergic reaction 16 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of patients of vaccine side effects after the COVID-19 vaccine

Gedik

Kilci

Hakkoymaz

et al. 2023

Rev. Assoc. Med. Bras.

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OBJECTIVE: Postvaccine side effects were evaluated in patients presenting to our emergency department with complaints of vaccine side effects after taking COVID-19 vaccine, and new unknown side effects ranging from mild complaints to life-threatening risks, and frequency of all side effects were investigated. This study aimed to establish a scientific resource to identify the potential side effects of the vaccine. METHODS: Patients' demographic information, clinical characteristics, epicrisis reports, COVID-19 disease and vaccination histories, vital values, and blood values were examined. The SPSS 20.0 package program was used for statistical evaluation. p<0.05 was considered statistically significant. RESULTS: Notably, 13.1% of patients presenting to the emergency department started to have complaints after taking Sinovac vaccine, whereas 86.9% of them had complaints after taking BioNTech vaccine. Also, 36.9% of patients stated that they had COVID-19. All patients had a Glasgow coma scale score of 15 during admission. No patient was hospitalized, ventilator was not needed, and all patients were discharged. While the most common presenting complaint to the emergency department after vaccination was fatigue in 29.7%, the most common diagnoses after examination in the emergency department were myalgia in 32.1% and upper respiratory tract infection in 28.6%. CONCLUSION: Results and conclusions of our study will guide healthcare workers and patients on the side effects of COVID-19 vaccine.

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“…Vaccines may require medical support in patients depending on their side effects (31,32). A review of the literature shows that 0.13% of healthcare workers in Sri Lanka who received the Oxford/AstraZeneca vaccine required hospitalization, while 22.4% required 24-48 hours of rest, and nearly 70% continued to work (20).…”

Section: Discussionmentioning

confidence: 99%

“…In a study examining those admitted to the emergency room after vaccination against COVID-19, 85% of patients received treatment within a day of vaccination and 17.9% were hospitalized. Shortness of breath, chest pain, and allergic reactions were the three most common complaints in these emergency admissions (32). Regarding the side effects of the vaccine, according to the WHO Global Advisory Committee, symptoms can last between 4 and 12 days if those who have severe symptoms after vaccination receive medical treatment (23).…”

Section: Discussionmentioning

confidence: 99%

Kuzeybatı Suriye'de COVID-19 aşısı ile ilk aşılanan sağlık çalışanlarının değerlendirilmesi: Acil servislerde aşı yan etkisi gözlemleri

Karaca

ÇELİK

2022

Genel Tıp Dergisi

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Aim In this study, we investigated the adverse effects of the COVID-19 vaccine administered to health workers in northwestern Syria. Materials and Methods The study retrospectively analyzed data from 260 health care workers who received the first dose of COVID-19 vaccine between May 1, 2021, and June 30, 2021, in the northwestern Syria region by searching the Syrian Immunization Group database (SIG) and patient records from hospital or health center emergency departments. Results The mean age of health care personnel was 35.86∓8.03 years, and 9.6% were women. Of those who participated in the study, 5.8% had comorbid diseases. 109 (42.1%) were vaccinated in hospital emergency departments and 151 (57.9%) in health center emergency departments. It was found that 63.5% (n=165) of those vaccinated experienced adverse reactions to the Oxford/AstraZeneca vaccine. The most common adverse reactions to the vaccine were fever in 128 individuals (49%), fatigue in 89 individuals (55.6%), headache in 54 individuals (20.8%), weakness in 53 individuals (20.4%), joint pain in 50 individuals (19.2%), injection site pain in 47 individuals (18.1%), and muscle pain in 33 individuals (12.7%). The side effects noted were classified as severe, moderate, and mild. Of these, fever 15.4% (n=40), fatigue 11.9% (n=31), and headache 9.6% (n=25) were the most common severe side effects. It was found that 14 (5.4%) individuals required hospitalization and medical treatment due to adverse reactions to the vaccine. When evaluating the side effects observed in hospitalized patients, the most common side effects were fever, chills, muscle pain, joint pain, fatigue, and weakness. Conclusion It was concluded that the Oxford/AstraZeneca vaccine administered to health care workers in northwestern Syria had no fatal side effects and that fewer side effects were generally observed in this study compared with the literature. Research on side effects through independent studies will help address global and regional concerns about vaccines.

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COVID-19 vaccine adverse reactions bring patients to emergency departments

Cited by 5 publications

References 2 publications

Efficacy of Non-Enhanced Brain Computed Tomography in Patients Presenting to the Emergency Department with Headache after COVID-19 Vaccination

Efficacy of Non-Enhanced Brain Computed Tomography in Patients Presenting to the Emergency Department with Headache after COVID-19 Vaccination

Evaluation of patients of vaccine side effects after the COVID-19 vaccine

Kuzeybatı Suriye'de COVID-19 aşısı ile ilk aşılanan sağlık çalışanlarının değerlendirilmesi: Acil servislerde aşı yan etkisi gözlemleri

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