2021
DOI: 10.12746/swrccc.v9i37.801
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COVID-19 vaccination: an attempt to control the pandemic

Abstract: Background: Since the Severe Acute Respiratory Syndrome Coronavirus-2 was discovered in December 2019, there have been tireless efforts by the medical and scientific community to understand its pathophysiology, treatment, and prevention. Discussion: In the last several months, several therapeutic treatments, including a corticosteroid, antiviral drugs, convalescent plasma, and several others, have been tried in the treatment of SARS-CoV-2 with varying results. Pfizer and Moderna COVID-19 vaccines recentl… Show more

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Cited by 6 publications
(5 citation statements)
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“…In general, herd immunity can be achieved either through vaccination or the natural infection of the majority of the population; thereby, infected or vaccinated individuals gain humoral as well as cellular immunity to combat future infections [ 4 , 5 ]. For deadly diseases such as COVID-19, obtaining herd immunity through natural infection is a setback as it leads to a significant number of deaths in a population [ 13 ]. Hence, the alternative is to vaccinate the general population, which currently serves as the only effective method to ensure a significant decrease in the spread of the disease without placing more lives at risk.…”
Section: Introductionmentioning
confidence: 99%
“…In general, herd immunity can be achieved either through vaccination or the natural infection of the majority of the population; thereby, infected or vaccinated individuals gain humoral as well as cellular immunity to combat future infections [ 4 , 5 ]. For deadly diseases such as COVID-19, obtaining herd immunity through natural infection is a setback as it leads to a significant number of deaths in a population [ 13 ]. Hence, the alternative is to vaccinate the general population, which currently serves as the only effective method to ensure a significant decrease in the spread of the disease without placing more lives at risk.…”
Section: Introductionmentioning
confidence: 99%
“…On October 12, the company announced that it would pause their clinical trials due to a participant experiencing an unexplained illness. It halted the trials to investigate the reaction's nature to determine whether it was related to the vaccine given [97]. Nevertheless, 11 days after the report, Johnson & Johnson resumed the trials after concluding that the medical event had no clear indication that it was related to the vaccine.…”
Section: Recombinant Viral Vector Vaccinesmentioning
confidence: 99%
“…Vaccination is perhaps the preferred choice for controlling COVID-19 [ 207 , 208 ]. Epitopes, mRNA, and S protein-RBD structure-based vaccines have been widely proposed and started [ 209 ].…”
Section: Medical Interventions: Antiviral Therapies and Vaccinesmentioning
confidence: 99%