2020
DOI: 10.58969/25947125.4.0.2020.108
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COVID 19, uma doença sistêmica

Abstract: A COVID 19 é uma doença complexa, multissistêmica e que evolui em fases cujos sintomas e prognóstico depende da fase em que o paciente se encontra. Embora a característica clínica fundamental da doença por COVID-19 seja respiratória, também existem complicações neurológicas, renais, digestivas, cardíacas e em outros órgãos, sendo relacionado com a presença de receptores para ACE2 em tais órgãos. Ainda existem dúvidas se todos os sintomas da COVID 19 são secundários à inflamação ou se pode existir um componente… Show more

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Cited by 4 publications
(3 citation statements)
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“…Given the consequences of SARS-CoV-2, patients may exhibit respiratory symptoms and experience involvement of various body systems such as the nervous, renal, digestive, and cardiovascular systems [ 16 ]. The multisystem nature of the disease often necessitates invasive procedures to support organ functions [ 2 ]. The diverse manifestations and clinical presentations of COVID-19 justify the presence of a wide range of NDs, encompassing both risk-focused and problem-focused diagnoses.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Given the consequences of SARS-CoV-2, patients may exhibit respiratory symptoms and experience involvement of various body systems such as the nervous, renal, digestive, and cardiovascular systems [ 16 ]. The multisystem nature of the disease often necessitates invasive procedures to support organ functions [ 2 ]. The diverse manifestations and clinical presentations of COVID-19 justify the presence of a wide range of NDs, encompassing both risk-focused and problem-focused diagnoses.…”
Section: Discussionmentioning
confidence: 99%
“…In January of the same year, the World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC) to mitigate the widespread transmission of the virus. Consequently, in March 2020, considering the extensive geographic spread of COVID-19, it was classified as a pandemic state [ 1 , 2 ].…”
Section: Introductionmentioning
confidence: 99%
“…This is due to the high affinity of SARS-CoV-2 for the transmembrane angiotensin-converting enzyme 2 (ACE2) protein, which is found in various tissues such as the kidneys, heart, lungs, and endothelial cells (Scholz et al, 2020). This results in an overproduction of inflammatory cytokines, leading to tissue damage in ACE2-expressing organs and increasing the risk for patients with pre-existing comorbidities (Barjud., 2020).…”
Section: Discussionmentioning
confidence: 99%