COVID-19 severe acute respiratory syndrome in Brazilian newborns in 2020-2021

Abstract

Objective: To describe the clinical characteristics of cases of COVID-19 severe acute respiratory syndrome (SARS) in Brazilian newborns (NBs) in 2020 and 2021, recorded in the Influenza Epidemiological Surveillance Information System (Sistema de Informação da Vigilância Epidemiológica da Gripe — SIVEP-Gripe). Methods: The variables analyzed were gender, race/skin color, hospitalization, intensive care unit (ICU) admission, use of ventilatory support, signs and symptoms (fever, cough, O2 saturation<95%, dyspnea, respiratory distress, diarrhea, and vomiting), progress (death or cure), risk factors/comorbidities. Categorical variables were expressed as absolute and relative frequencies. Results: We found 1,649 records of COVID-19 SARS in NBs, with a predominance of multiracial babies in both years. The most frequent symptoms in 2020 and 2021 were, respectively: respiratory distress (67.0 and 69.7%), fever (46.3 and 46.2%), and cough (37.0 and 46.3%). In 2020, 30.5% of patients received invasive ventilatory support; in 2021, this number was 41.6%. In addition, more than 55% of cases required ICU admission, and over 16% died. Conclusion: We emphasize the high proportion of cases that required intensive care and progressed to death.

survInTime - Exploring surveillance methods and data analysis on Brazilian respiratory syndrome dataset and community mobility changes

“…In relation to the number of days passed between the notification to the outcome the most common values ranged form 3 to 6, corresponding together to 27.6% of the cases. Finally, the cities that received more people from other ones were São José do Rio Preto (7,218 cases), São Bernado do Campo (6,378) and Campinas (4,421).…”

“…In order to guarantee the correct integration with the mobility change dataset, another filtering step removed the rows with residence and notification cities empty or that did not match the correct names registered in the last brazilian census. The Brazilian Institute of Geography and Statistics recently released the update population number of 5570 cities according to the 2022 census 6 . We integrated the brazilian states information 7 together with the respective cities and their population to facilitate analysis and curate the residence and notification city fields.…”

“…This database contains more than 3 million records but not all cities are represented in it neither the most part of the asymptomatic cases. The epidemiological works [3][4][5][6][7][8][9][10] published about the disease spread and cases simulation and projection clearly demonstrated the discrepancies between the data reported and the real number of cases and deaths across the Brazilian cities. However, few works provided integration and methodological approaches to diagnose and extract useful insights from this data.…”