2020
DOI: 10.3138/cpp.2020-107
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COVID-19’s Limited Impact on Drug Shortages in Canada

Abstract: Analysant les données du site Web Pénuries de médicaments Canada, l'auteur se demande si les premiers mois de la pandémie causée par le coronavirus 2019 (COVID-19) ont été associés à une hausse importante des pénuries de médicaments au Canada. La hausse qu'il observe dans le nombre de pénuries signalées par les fabricants au cours des mois de mars et avril 2020, par rapport aux mêmes mois des années précédentes, s'établit à 147 (soit 32 pour cent). Cette hausse est concentrée dans la période de deux semaines s… Show more

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Cited by 6 publications
(9 citation statements)
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“…Participants experienced multiple disruptions to gender-afrming care during the frst three waves of COVID-19 in Canada [18]. COVID-19 lockdowns and travel restrictions afected the supply chain for medications nationwide [52,53]. For our participants, this impacted their ability to access hormone therapy.…”
Section: Barriers To Gender-afrming Health Services During Covid-19mentioning
confidence: 99%
“…Participants experienced multiple disruptions to gender-afrming care during the frst three waves of COVID-19 in Canada [18]. COVID-19 lockdowns and travel restrictions afected the supply chain for medications nationwide [52,53]. For our participants, this impacted their ability to access hormone therapy.…”
Section: Barriers To Gender-afrming Health Services During Covid-19mentioning
confidence: 99%
“…Low supply of sedative agents along with many other drugs stemmed from disruption of drug supply chains in China and India that are pivotal in the production of the active ingredients of many agents [ 10 ]. Drug shortages are not a new phenomenon [ 11 ], but the universal surge in demand for the same sedative therapeutics, rapid change in drug purchasing patterns, scaling up and shipping problems led to major drug shortage crises [ 12 ]. The increased demand for sedatives was in part fuelled by higher sedative needs and longer duration of sedation in COVID-19 patients compared with other intubated respiratory failure patients [ 13 ].…”
Section: Where We Werementioning
confidence: 99%
“…In contrast to intravenous sedatives, inhaled anaesthetics have no active metabolites and are cleared primarily by exhalation, which prevents their build up in settings of hepatorenal dysfunction commonly accompanying critical illness. Inhaled anaesthetics are potent bronchodilators, which facilitates secretion clearance and gas exchange, and they are often used as rescue medications in patients with the most severe forms of respiratory failure such as status asthmaticus [ 12 ]. Finally, inhaled anaesthetics may reduce inflammation and pulmonary epithelial injury, which translated into improved oxygenation and a trend towards shorter duration of ventilation in pilot randomized controlled trial of patients with acute respiratory distress syndrome [ 20 ].…”
Section: Repurposing Inhaled Anesthetics As Alternative Icu Sedativesmentioning
confidence: 99%
“…Public sector procurement is central to adequately responding to crisis situations, such as the new coronavirus pandemic, and requires governments to have the ability to select and assemble the necessary materials at short notice to trigger effective delivery of government services (Atkinson et al, 2020). In this context, the purchase may run into difficulties, in view of the increase in demand, the low availability of raw materials of manufacturing inputs and finished products, besides the increase in prices (Amaya et al, 2021;Gaudette, 2020).…”
Section: Introductionmentioning
confidence: 99%