COVID-19's impact on Australia's health research workforce

Peeters, Anna; Mullins, Greg; Becker, Denise; Orellana, Liliana; Livingston, Patricia M.

doi:10.1016/s0140-6736(20)31533-6

Cited by 22 publications

(20 citation statements)

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“…In another survey conducted by Research Australia in May 2020, an inability to perform remote research was identified as a major issue affecting over 50% of participants. It was also highlighted that research outcomes among basic science researchers were more likely to be affected after the year 2020, in comparison to clinical researchers [ 17 ].…”

Section: Impact On Basic Sciencementioning

confidence: 99%

Impact of the coronavirus (COVID-19) pandemic on scientific research and implications for clinical academic training – A review

Sohrabi

Mathew

Franchi

et al. 2021

International Journal of Surgery

130

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Section: Impact On Basic Sciencementioning

confidence: 99%

Impact of the coronavirus (COVID-19) pandemic on scientific research and implications for clinical academic training – A review

Sohrabi

Mathew

Franchi

et al. 2021

International Journal of Surgery

130

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“…Support from the ethics committee has been crucial for limiting the cessation of research practices. Other Australian researchers have likewise noted shortened time frames for ethics committee procedures, thus allowing research to adapt rapidly in line with current (COVID-19 era) requirements [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

New Methodologies for Conducting Maternal, Infant, and Child Nutrition Research in the Era of COVID-19

et al. 2021

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The severe acute respiratory syndrome coronavirus disease 2019 (COVID-19) outbreak rapidly became a worldwide pandemic in early 2020. In Australia, government-mandated restrictions on non-essential face-to-face contact in the healthcare setting have been crucial for limiting opportunities for COVID-19 transmission, but they have severely limited, and even halted, many research activities. Our institute’s research practices in the vulnerable populations of pregnant women and young infants needed to adapt in order to continue without exposing participants, or staff, to an increased risk of exposure to COVID-19. Here, we discuss our pre-and-post COVID-19 methods for conducting research regarding nutrition during pregnancy, infancy, and early childhood. We discuss modifications to study methods implemented to avoid face-to-face contact when identifying and recruiting potential participants, gaining informed consent, conducting appointments, and collecting outcome data, and the implications of these changes. The COVID-19 pandemic has required numerous changes to the conduct of research activities, but many of those modifications will be useful in post-COVID-19 research settings.

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“…Increased risk of a wide range of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease, has long been recognized following exposure to TBI outside of a sporting context. Indeed, an estimated 3–10% of dementia in the community is thought to be influenced by prior exposure to TBI [ 9 , 14 , 24 ]. Despite this we know remarkably little about the pathophysiology and pathologies of TBI-related neurodegeneration (TReND), within which CTE represents just one of several late consequences of TBI [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

“…Exposure to a TBI is acknowledged as one of the strongest environmental risk factors for early cognitive decline and dementia [ 5 , 14 , 15 , 21 ], with a clinical phenotype typically reported similar to AD [ 4 , 21 ]. However, prior studies on the etiology of dementia associated with TBI used chart reviews or clinical interviews for dementia ascertainment, which are recognized to have a low specificity [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…As TReND is increasingly recognized as a major health concern [ 14 ], there is a clear and pressing need to adequately characterize the spectrum, extent and neuroanatomic distribution of the pathologies emerging in those exposed to TBI and their relationship to wider pathologies of aging and neurodegeneration. In so doing, robust operational criteria for late TBI-related neuropathologies will be defined, which will, in turn, be critical to the development of robust diagnostic, mechanistic and interventional studies.…”

Section: Introductionmentioning

confidence: 99%

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COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)

Smith

Dollé

Ameen‐Ali

et al. 2021

acta neuropathol commun

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Efforts to characterize the late effects of traumatic brain injury (TBI) have been in progress for some time. In recent years much of this activity has been directed towards reporting of chronic traumatic encephalopathy (CTE) in former contact sports athletes and others exposed to repetitive head impacts. However, the association between TBI and dementia risk has long been acknowledged outside of contact sports. Further, growing experience suggests a complex of neurodegenerative pathologies in those surviving TBI, which extends beyond CTE. Nevertheless, despite extensive research, we have scant knowledge of the mechanisms underlying TBI-related neurodegeneration (TReND) and its link to dementia. In part, this is due to the limited number of human brain samples linked to robust demographic and clinical information available for research. Here we detail a National Institutes for Neurological Disease and Stroke Center Without Walls project, the COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI), designed to address current limitations in tissue and research access and to advance understanding of the neuropathologies of TReND. As an international, multidisciplinary collaboration CONNECT-TBI brings together multiple experts across 13 institutions. In so doing, CONNECT-TBI unites the existing, comprehensive clinical and neuropathological datasets of multiple established research brain archives in TBI, with survivals ranging minutes to many decades and spanning diverse injury exposures. These existing tissue specimens will be supplemented by prospective brain banking and contribute to a centralized route of access to human tissue for research for investigators. Importantly, each new case will be subject to consensus neuropathology review by the CONNECT-TBI Expert Pathology Group. Herein we set out the CONNECT-TBI program structure and aims and, by way of an illustrative case, the approach to consensus evaluation of new case donations.

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COVID-19's impact on Australia's health research workforce

Cited by 22 publications

References 0 publications

Impact of the coronavirus (COVID-19) pandemic on scientific research and implications for clinical academic training – A review

Impact of the coronavirus (COVID-19) pandemic on scientific research and implications for clinical academic training – A review

New Methodologies for Conducting Maternal, Infant, and Child Nutrition Research in the Era of COVID-19

COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)

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