COVID-19 quarantine and acute pulmonary embolism

Vannini, Luca; Gómez, Joaquín Marchena; Quijada-Fumero, Alejandro; Pérez, Ana Belén Fernández; Hernández-Afonso, Julio

doi:10.1016/j.rec.2020.05.010

Cited by 7 publications

(8 citation statements)

References 4 publications

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“…Kayani et al recently reported that COVID-19-positive hip fracture patients had a 13.4% rate of TED at 30-day follow-up [7]. However, Vannini et al also reported on a higher rate of acute embolic events in COVID-19negative patients, associating it to prolonged immobility due to rigid quarantine dispositions [31]. Extended confinement times leading to both reduced physical activity [14] and family care may exacerbate sedentary behaviours and indirectly contribute to thromboembolic events in an already vulnerable population [32].…”

Section: Discussionmentioning

confidence: 99%

Prolonged social lockdown during COVID-19 pandemic and hip fracture epidemiology

Slullitel

Lucero

Soruco

et al. 2020

International Orthopaedics (SICOT)

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Purpose To analyse the impact of prolonged mandatory lockdown due to COVID-19 on hip fracture epidemiology. Methods Retrospective case-control study of 160 hip fractures operated upon between December 2019 and May 2020. Based on the date of declaration of national lockdown, the cohort was separated into two groups: 'pre-COVID time' (PCT), including 86 patients, and 'COVID time' (CT), consisting of 74 patients. All CT patients tested negative for SARS-CoV-2. Patients were stratified based on demographic characteristics. Outcome measures were 30-day complications, readmissions and mortality. A logistic regression model was run to evaluate factors associated with mortality. Results Age, female/male ratio, body mass index and American Society of Anaesthesia score were similar between both groups (p > 0.05). CT patients had a higher percentage of Charlson ≥ 5 and Rockwood Frailty Index ≥ 5 scores (p < 0.05) as well as lower UCLA and Instrumental Activities of Daily Living scores (p < 0.05). This translated into a higher hemiarthroplasty/total hip arthroplasty ratio during CT (p = 0.04). Thromboembolic disease was higher during CT (p = 0.02). Readmissions (all negative for SARS-CoV-2) were similar between both groups (p = 0.34). Eight (10.8%) casualties were detected in the CT group, whereas no deaths were seen in the control group. Logistic regression showed that frailer (p = 0.006, OR 10.46, 95%CI 8.95-16.1), less active (p = 0.018, OR 2.45, 95%CI 1.45-2.72) and those with a thromboembolic event (p = 0.005, OR 30, 95%CI 11-42) had a higher risk of mortality.

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Section: Discussionmentioning

confidence: 99%

Prolonged social lockdown during COVID-19 pandemic and hip fracture epidemiology

Slullitel

Lucero

Soruco

et al. 2020

International Orthopaedics (SICOT)

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“…Anticoagulation with sodium heparin, oxygen at 3 L / minute, and boluses of saline crystalloids was administered, with good outcome. The subsequent workup for other patient-related factor predisposing him for venous thromboembolism, revealed a Antiphospholipid Syndrome with evidence of a circulating anticoagulant (Lupus anticoagulant), (Table 2), and it was decided that the patient was going to remain anticoagulated in the long term Discussion: The present case study of acute PE makes a contribution to the field offering new evidence of the increased risk of high-risk thromboembolic situations in patients with unusual triggering factors, under the limited conditions and decrease in physical activity due to the SARS-COV2 Pandemic quarantine 1,2,3 , in this case, the presence of a Antiphospholipid Syndrome. A delay in consulting a physician due to a fear of becoming infected in health care areas increases this risk.…”

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confidence: 78%

Pulmonary Embolism Related to COVID 19 Quarentine

Quinteros¹,

Bisonni²

2020

Preprint

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“…Diagnosis of VTE disease, especially pulmonary embolism, in patients with SARS-CoV 2 infections are incredibly difficult and challenging. In most COVID-19 patients, no association was found between traditional major risk factors (age, history of VTE disease, malignancy history, smoking and cardiovascular comorbidities including diabetes, hypertension, chronic heart failure and coronary artery disease) and VTE diseases 15 , 24 , 25 . Male gender and obesity were risk factors directly associated with an increased incidence of pulmonary embolism 15 , 16 , 26 .…”

Section: Vte Diagnosis In Covid-19 Patientsmentioning

confidence: 93%

“…Therefore, using Wells and Geneva risk scores to predict the occurrence of pulmonary embolism is of low value and difficult 25 , 27 . As the first para-clinical approach in the diagnostic algorithm of pulmonary embolism, the use of D-dimer in the patients admitted with SARS-CoV 2 infection is controversial, because this marker has been increased as an acute reaction factor in hospitalized patients in need of respiratory care and loses its predictive value due to its low specificity 28 .…”

Section: Vte Diagnosis In Covid-19 Patientsmentioning

confidence: 99%

A Review of Venous Thromboembolism Phenomena in COVID-19 Patients

Kermani-Alghoraishi

Ghahramani

2021

Current Problems in Cardiology

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With the outbreak of the second peak of COVID-19 in many countries of the world, re-attention to the symptoms and complications of this disease has received much attention. One of the most important known complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the occurrence of venous thromboembolic (VTE) events, especially in critically ill patients and hospitalized in the intensive care unit. The pathology of this event is complex and multifactorial, but the main problem now is the timely diagnosis of these phenomena, which can reduce the mortality and morbidity of patients. Deterioration of clinical condition in patients with SARS-CoV-2 infection along with increased coagulation markers can increase clinical suspicion of VTE events. Imaging techniques, especially computed tomography pulmonary angiography, can well solve this puzzle and lead to timely treatment of these patients.

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COVID-19 quarantine and acute pulmonary embolism

Cited by 7 publications

References 4 publications

Prolonged social lockdown during COVID-19 pandemic and hip fracture epidemiology

Prolonged social lockdown during COVID-19 pandemic and hip fracture epidemiology

Pulmonary Embolism Related to COVID 19 Quarentine

A Review of Venous Thromboembolism Phenomena in COVID-19 Patients

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