COVID-19 Pandemic Impact on Trajectories in Cardiometabolic Health, Physical Activity, and Functioning Among Adults from the 2006–2020 Health and Retirement Study

Beydoun, Hind A.; Beydoun, May A.; Gautam, Rana S.; Alemu, Brook T.; Weiss, Jordan; Hossain, Sharmin; Zonderman, Alan B.

doi:10.1093/gerona/glac028

Cited by 13 publications

(23 citation statements)

References 57 publications

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“…The original HRS study consists of participants from whom data were collected in 1992, 1994 and 1996, and the Study of Asset and Health Dynamics of the Oldest Old (AHEAD) consists of those from whom data were collected in 1993 and 1995 38 , 39 . The two studies were merged and two new generations (the Children of the Depression and the War Babies) were added in 1998.…”

Section: Methodsmentioning

confidence: 99%

“…The two studies were merged and two new generations (the Children of the Depression and the War Babies) were added in 1998. Subsequently, Early Baby Boomers were added in 2004, Mid Baby Boomers were added in 2010 and Late Baby Boomers were added in 2016 38 , 39 . Starting in 2006, half of the sample completed detailed in-person interviews that included physical, biological and psychosocial measures, and the other half completed a core interview by telephone 38 , 39 .…”

Section: Methodsmentioning

confidence: 99%

“…Subsequently, Early Baby Boomers were added in 2004, Mid Baby Boomers were added in 2010 and Late Baby Boomers were added in 2016 38 , 39 . Starting in 2006, half of the sample completed detailed in-person interviews that included physical, biological and psychosocial measures, and the other half completed a core interview by telephone 38 , 39 . To reduce study-related costs and burden on participants, enhanced interviewing alternated among half-samples at each subsequent wave 38 , 39 .…”

Section: Methodsmentioning

confidence: 99%

“…Starting in 2006, half of the sample completed detailed in-person interviews that included physical, biological and psychosocial measures, and the other half completed a core interview by telephone 38 , 39 . To reduce study-related costs and burden on participants, enhanced interviewing alternated among half-samples at each subsequent wave 38 , 39 . This sample was restricted to HRS participants for whom data were collected during 2006, 2008, 2010, 2012, 2014, 2016 and/or 2018 (before Covid-19) waves as well as the 2020 (Covid-19) wave whereby enhanced interviewing was conducted by telephone due to social distancing restrictions 38 .…”

Section: Methodsmentioning

confidence: 99%

“…To reduce study-related costs and burden on participants, enhanced interviewing alternated among half-samples at each subsequent wave 38 , 39 . This sample was restricted to HRS participants for whom data were collected during 2006, 2008, 2010, 2012, 2014, 2016 and/or 2018 (before Covid-19) waves as well as the 2020 (Covid-19) wave whereby enhanced interviewing was conducted by telephone due to social distancing restrictions 38 . Release to fieldwork occurred sequentially on June 11, 2020 and September 24, 2020 for the 2020 HRS Covid-19 project 38 .…”

Section: Methodsmentioning

confidence: 99%

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Predictors of Covid-19 level of concern among older adults from the health and retirement study

Beydoun

Weiss

et al. 2022

Sci Rep

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The purpose of this longitudinal study is to construct a prediction model for Covid-19 level of concern using established Covid-19 socio-demographic, lifestyle and health risk characteristics and to examine specific contributions of obesity-related cardiometabolic health characteristics as predictors of Covid-19 level of concern among a representative sample of U.S. older adults. We performed secondary analyses of existing data on 2872 2006–2020 Health and Retirement Study participants and examined 19 characteristics in relation to the outcome of interest using logistic regression and machine learning algorithms. In mixed-effects ordinal logistic regression models, a history of diabetes, stroke as well as 1–2 cardiometabolic risk factors and/or chronic conditions were associated with greater Covid-19 level of concern, after controlling for confounders. Female sex, birth cohort, minority race, Hispanic ethnicity and total wealth as well as depressive symptoms were associated with higher level of Covid-19 concern, and education was associated with lower level of Covid-19 concern in fully adjusted mixed-effects ordinal logistic regression models. The selected socio-demographic, lifestyle and health characteristics accounted for < 70% of the variability in Covid-19 level of concern based on machine learning algorithms. Independent risk factors for Covid-19 level of concern among U.S. older adults include socio-demographic characteristics and depressive symptoms. Advanced research is needed to identify relevant predictors and elucidate underlying mechanisms of observed relationships.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Predictors of Covid-19 level of concern among older adults from the health and retirement study

Beydoun

Weiss

et al. 2022

Sci Rep

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Effect of Personalized Risk-Reduction Strategies on Cognition and Dementia Risk Profile Among Older Adults

Yaffe,

Vittinghoff,

Dublin

et al. 2024

JAMA Intern Med

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ImportanceModifiable risk factors are hypothesized to account for 30% to 40% of dementia; yet, few trials have demonstrated that risk-reduction interventions, especially multidomain, are efficacious.ObjectiveTo determine if a personalized, multidomain risk reduction intervention improves cognition and dementia risk profile among older adults.Design, Setting, and ParticipantsThe Systematic Multi-Domain Alzheimer Risk Reduction Trial was a randomized clinical trial with a 2-year personalized, risk-reduction intervention. A total of 172 adults at elevated risk for dementia (age 70-89 years and with ≥2 of 8 targeted risk factors) were recruited from primary care clinics associated with Kaiser Permanente Washington. Data were collected from August 2018 to August 2022 and analyzed from October 2022 to September 2023.InterventionParticipants were randomly assigned to the intervention (personalized risk-reduction goals with health coaching and nurse visits) or to a health education control.Main Outcomes and MeasuresThe primary outcome was change in a composite modified Neuropsychological Test Battery; preplanned secondary outcomes were change in risk factors and quality of life (QOL). Outcomes were assessed at baseline and 6, 12, 18, and 24 months. Linear mixed models were used to compare, by intention to treat, average treatment effects (ATEs) from baseline over follow-up. The intervention and outcomes were initially in person but then, due to onset of the COVID-19 pandemic, were remote.ResultsThe 172 total participants had a mean (SD) age of 75.7 (4.8) years, and 108 (62.8%) were women. After 2 years, compared with the 90 participants in the control group, the 82 participants assigned to intervention demonstrated larger improvements in the composite cognitive score (ATE of SD, 0.14; 95% CI, 0.03-0.25; P = .02; a 74% improvement compared with the change in the control group), better composite risk factor score (ATE of SD, 0.11; 95% CI, 0.01-0.20; P = .03), and improved QOL (ATE, 0.81 points; 95% CI, −0.21 to 1.84; P = .12). There were no between-group differences in serious adverse events (24 in the intervention group and 23 in the control group; P = .59), but the intervention group had greater treatment-related adverse events such as musculoskeletal pain (14 in the intervention group vs 0 in the control group; P &lt; .001).Conclusions and RelevanceIn this randomized clinical trial, a 2-year, personalized, multidomain intervention led to modest improvements in cognition, dementia risk factors, and QOL. Modifiable risk-reduction strategies should be considered for older adults at risk for dementia.Trial RegistrationClinicalTrials.gov Identifier: NCT03683394

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COVID‐19 pandemic experiences of older adults with dementia in community and residential care settings: Results from a US national survey

Schrack

Corkum

Freedman

2022

Alz & Dem Diag Ass & Dis Mo

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Introduction Investigations into consequences of the US COVID‐19 pandemic for older adults with dementia have been limited. Methods We used the National Health and Aging Trends Study to examine self‐reported COVID‐19 infection; measures taken to limit its spread; social, behavioral, and emotional responses to the pandemic; and changes in health‐care use and provider communication. We compared adults aged ≥70 with and without dementia in community and residential care settings. Results In residential care settings, infection was substantially higher and social contact less common for those with dementia. In community and residential care settings, those with dementia had 2 to 3 times the odds of reporting sleeping more often. In residential care settings, those with dementia were less likely to put off care and more likely to start telehealth. Discussion Findings highlight the disproportionate social and behavioral consequences of the COVID‐19 pandemic for those living with dementia, particularly in residential care settings. HIGHLIGHTS Data are from the nationally representative National Health and Aging Trends Study. COVID‐19 infection was higher in residential care settings for those with dementia. Social contact was less common for those with dementia in residential care. Pandemic‐related coping behaviors differed by dementia and residential status. In residential care, those with dementia were less likely to delay health care.

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COVID-19 Pandemic Impact on Trajectories in Cardiometabolic Health, Physical Activity, and Functioning Among Adults from the 2006–2020 Health and Retirement Study

Cited by 13 publications

References 57 publications

Predictors of Covid-19 level of concern among older adults from the health and retirement study

Predictors of Covid-19 level of concern among older adults from the health and retirement study

Effect of Personalized Risk-Reduction Strategies on Cognition and Dementia Risk Profile Among Older Adults

COVID‐19 pandemic experiences of older adults with dementia in community and residential care settings: Results from a US national survey

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