COVID-19 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women?

Rotshenker-Olshinka, Keren; Volodarsky‐Perel, Alexander; Steiner, Naama; Rubenfeld, Eryn Sarah; Dahan, Michael H.

doi:10.1007/s00404-020-05848-0

Cited by 41 publications

(43 citation statements)

References 14 publications

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“…7,11,12,15,26 One casecontrol study found no difference in the incidence of COVID-19 infection in women with and without firsttrimester spontaneous pregnancy loss, while a retro-spective study found no differences in viable and arrested pregnancies among women who presented for a first-trimester viability scan in the COVID and pre-COVID time periods. 27,28 The inclusion of only detected pregnancies and reported losses may bias the results of these studies. A retrospective study of pregnancies resulting from IVF or intrauterine insemination reported a miscarriage rate of 14.4% from December 2019 to March 2020, although the lack of a comparison group in this study limits the interpretation of this finding.…”

Section: Discussionmentioning

confidence: 99%

The Impact of the Coronavirus Disease 19 Pandemic on Early Pregnancy Outcomes Among Patients Undergoing In Vitro Fertilization Treatment

Aharon

Gounko

Lee

et al. 2021

Women's Health Reports

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Objective: To determine if pregnancy rates (PRs) or pregnancy loss rates (PLRs) were altered in patients undergoing single, euploid frozen-thawed embryo transfer (FET) during the initial peak of the Coronavirus Disease 19 (COVID-19) pandemic. Materials and Methods: This was a retrospective cohort study performed in a single academic center. Patients undergoing single, euploid FET cycles from January to May 2017-2020 were included. Cycles with FET performed in January-May of 2020 (''COVID-surge cohort'') were compared to cycles with FET performed in January-May of 2017-2019 (''pre-COVID cohort''). Pregnancy rate (PR), clinical pregnancy rate (CPR), pregnancy loss rate (PLR), and clinical pregnancy loss rate (CLR) were compared between the cohorts.

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Section: Discussionmentioning

confidence: 99%

The Impact of the Coronavirus Disease 19 Pandemic on Early Pregnancy Outcomes Among Patients Undergoing In Vitro Fertilization Treatment

Aharon

Gounko

Lee

et al. 2021

Women's Health Reports

View full text Add to dashboard Cite

show abstract

“…Although there is insufficient evidence available to comment clearly on the risk of miscarriage, risk factors related to miscarriage have been discussed in the literature. A study investigating the effect of the stressful COVID-19 pandemic environment on early pregnancy concluded that in asymptomatic pregnant women the COVID-19 environment did not seem to affect first trimester miscarriage rates [ 67 ].…”

Section: Effect Of Covid-19 On Neonatal Outcomesmentioning

confidence: 99%

Effects of the COVID pandemic on pregnancy outcomes

Elsaddig

Khalil

2021

Best Practice & Research Clinical Obstetrics & Gynaecol

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Pregnant women and neonates are often categorised as being at high risk during the coronavirus-19 (COVID-19) pandemic. Numerous studies have demonstrated that the characteristics of COVID-19 disease in pregnant women and non-pregnant women are very similar. However, pregnant women with COVID-19 in the third trimester are more likely than their non-pregnant counterparts to require intensive care, though this may reflect a lower threshold for intervention in pregnant women rather than more serious disease. Compared with pregnant women without COVID-19, pregnant women with symptomatic COVID-19 requiring admission to hospital have worse maternal outcomes, including death, although the absolute risk remains very low. Outcomes of neonates born to women positive for COVID-19 are generally very good, though iatrogenic preterm birth is more common. Findings from these studies highlight the need for further monitoring of the outcomes of pregnant and post-partum women according to trimester during this pandemic.

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“…22 Furthermore, SARS-CoV-2 infection does not alter the nuchal translucency or any of the other ultrasound signs used to screen for Trisomy 21 in the first trimester of pregnancy. [23][24] Although encouraging, data from early pregnancy are still limited and mostly refer to non-hospitalized and/or asymptomatic women. Finally, no specific anomaly has been reported to be associated with the infection.…”

Section: Which Are the Fetal Risks Of Sars-cov-2 Infection?mentioning

confidence: 99%