COVID -19 pandemic and paediatric population with special reference to congenital heart disease

Childhood Multisystem Inflammatory Syndrome: An Emerging Disease with Prominent Cardiovascular Involvement—A Scoping Review

“…Out of all the reported cases, almost three fourths of the children were previously healthy although some studies have reported more prevalence of obesity, overweight and asthma in their observational cohorts. This pattern is in stark contrast with acute Covid-19 illness in children where infants and children with underlying medical conditions are prone to severe disease [4]. There is a definite lag period observed between the peaks of infection in community and peak of admissions for MIS-C cases [10,[18][19][20]22].…”

“…The ongoing pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-related coronavirus disease 2019 (Covid-19) is evolving at a rapid pace, and reports of newer manifestations of the disease are being reported worldwide. Children and adolescents affected by Covid-19 appear to have milder symptoms in the majority, less frequent severe disease and fewer hospitalizations as compared with adults [1][2][3] except for the infants and children with underlying comorbidities including congenital heart disease, who are at highest risk of complications of Covid-19 [4][5][6]. Recently several reports have described previously asymptomatic children affected with SARS-CoV-2 infection manifesting as a systemic hyperinflammatory status with multiorgan involvement (sometimes features reminiscent of Kawasaki disease) and prominent cardiogenic shock with myocardial dysfunction often requiring intensive care support.…”

COVID 19 pandemic: Its impact on cardiovascular training and care

“…There has been a total facelift in the management protocol from the pre-pandemic period to the present pandemic era especially evident in our cardiovascular management protocols. 33 , 34 , 35 …”

Factors affecting COVID-19 outcomes in patients with congenital heart disease

“…This may explain why patients with similar CHDs experience different disease trajectories. Therefore, using only the CHD status is not a sufficient indicator for poor outcomes and markers of symptom progression such as raised cardiac troponins upon admission may prove more useful [5]. This is particularly relevant since CHD patients with infection-induced myocardial injury are at a higher risk of complications [5].…”

“…Therefore, using only the CHD status is not a sufficient indicator for poor outcomes and markers of symptom progression such as raised cardiac troponins upon admission may prove more useful [5]. This is particularly relevant since CHD patients with infection-induced myocardial injury are at a higher risk of complications [5]. Treatment protocols used to manage infections should also be considered amongst the studies included https://www.cambridge.org/core/terms.…”