COVID-19: Outcomes of patients with confirmed COVID-19 re-admitted to hospital.

Rokadiya, Sakib; Gil, Eliza; Stubbs, Claire; Bell, Daniel; Herbert, Rachel

doi:10.1016/j.jinf.2020.07.007

Cited by 25 publications

(45 citation statements)

References 6 publications

(5 reference statements)

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“…The majority of readmissions with complications had ongoing respiratory symptoms in the absence of proven venous thromboembolism (16/31; 52%). This is similar to a recent letter in this Journal looking at readmissions at a London trust 3 and suggests that patients were being discharged optimistically from their primary admission. Deconditioning in the elderly was the second commonest complication (8/31; 26%) and suggests that clinical and social care post-discharge was not able to meet expectations.…”

supporting

confidence: 83%

Changes in the hospital admission profile of COVID-19 positive patients at a central London trust

Barnacle

Cairney

Rainsley

et al. 2021

Journal of Infection

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supporting

confidence: 83%

Changes in the hospital admission profile of COVID-19 positive patients at a central London trust

Barnacle

Cairney

Rainsley

et al. 2021

Journal of Infection

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“…In fact, most of the studies on COVID-19 primarily focused on epidemiological, clinical, biological and radiological characteristics of patients with confirmed SARS-CoV-2 infection. 2 However, only few studies addressed the importance of the follow-up of recovered patients.…”

mentioning

confidence: 99%

Positive RT-PCR nasopharyngeal swab in patients recovered from COVID-19 disease: When does quarantine really end?

Landi

Gremese

Rota

et al. 2020

Journal of Infection

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Positive RT-PCR nasopharyngeal swab in patients recovered from COVID-19 disease: When does quarantine really end? To the Editor , We read with great interest the review by Walsh and colleagues 1 summarising the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (including any asymptomatic or pre-symptomatic phase), and the duration of infectivity. Even though the authors concluded that the duration of COVID-19 infectivity remains uncertain, this is really an important issue for the international audience. In fact, most of the studies on COVID-19 primarily focused on epidemiological, clinical, biological and radiological characteristics of patients with confirmed SARS-CoV-2 infection. 2 However, only few studies addressed the importance of the follow-up of recovered patients. After the acute phase of SARS-CoV-2 epidemic infection, the Fondazione Policlinico A. Gemelli IRCSS of Rome established a post-acute care service for patients discharged from the hospital. Only the subjects who met the following WHO criteria for hospital discharge and/or discontinuation of quarantine have been admitted to the follow-up: a) subject must be fever-free without fever-reducing medications for three consecutive days; b) subject must show an improvement in any other symptoms, including reduced coughing and shortness of breath; c) at least seven days have passed since the onset of symptoms; d) in addition to these requirements, person must test negative for the SARS-CoV-2 virus twice, with the real-time reverse transcriptase-polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid taken at least 24 h apart. If the symptom and testing conditions are met, both WHO and US Centers for Disease Control and Prevention consider the subject officially recovered from COVID-19 disease. 3 During the first week of post-acute care activity, 29 patients recovered from COVID-19 disease were recalled being assessed. 4 , 5 Even though the patients were formally considered recovered from COVID-19 disease, a new RT-PCR test was repeated at the time of post-acute care admission. This study by the Catholic University / Fondazione Policlinico Gemelli IRCCS Institutional Ethics Committee (protocol ID number: 0 0130 08/20). Of the 29 patients who repeated the nasopharyngeal swab, 6 patients (20,6%) tested positive again. All these 6 patients were exposed to the SARS-CoV-2 infection at least one month before (Fig. 1). Three were male and the mean age was 59,0 ± 15,9 years (range from 37 to 78 years). All patients had fever as the onset of the COVID-19 infection. The other most frequently observed symptoms were cough, dyspnea, fatigue and dysgeusia. One patient reported symptoms of conjunctivitis, too. The mean number of days before admission to the hospital was 8,6 ± 3,1. All patients had positive RT-PCR test results at the time of hospital admission and the antero-posterior chest radiograph showing patchy ground-glass

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“…3 Finally, whilst neither of the Asian studies reports reattendance outcomes, the study from New York found a death rate of 3.4% and the one from London of 24% amongst those that required rehospitalization. 2,4 Early reattendance data may be particularly influenced by Overall, we find that reattendances following discharge from hospitalization for COVID-19 are common. Amidst the ongoing pandemic, maintaining an adequate clinical suspicion for cardiorespiratory and infectious conditions, among others, that may mimic or coexist with COVID-19 should not be undermined.…”

Section: Factors Associated With Reattendance To Emergency Services Fmentioning

confidence: 86%

“…More recently, a study from New York and one from another London hospital reported a median time to reattendance of 4.5 days amongst 103 patients 2 and 10 days amongst 25 patients, 4 respectively. Reattendance rates in these studies were 3.6% and 6.4%, respectively.…”

Section: Factors Associated With Reattendance To Emergency Services Fmentioning

confidence: 99%

“…Reattendance rates in these studies were 3.6% and 6.4%, respectively. 2,4 Another recent study from South Korea found that 328/ 7590 (4.3%) patients were readmitted within 3 days of discharge. 3 Importantly, in the latter study, a large portion of these patients were admitted due to recurrence of severe acute respiratory syndrome coronavirus 2 polymerase chain reaction positivity, regardless of clinical status.…”

Section: Factors Associated With Reattendance To Emergency Services Fmentioning

confidence: 99%

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Factors associated with reattendance to emergency services following COVID‐19 hospitalization

Daunt

Perez‐Guzman

Cafferkey

et al. 2020

Journal of Medical Virology

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COVID-19: Outcomes of patients with confirmed COVID-19 re-admitted to hospital.

Cited by 25 publications

References 6 publications

Changes in the hospital admission profile of COVID-19 positive patients at a central London trust

Changes in the hospital admission profile of COVID-19 positive patients at a central London trust

Positive RT-PCR nasopharyngeal swab in patients recovered from COVID-19 disease: When does quarantine really end?

Factors associated with reattendance to emergency services following COVID‐19 hospitalization

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