COVID-19 in Liver Transplant Recipients - Preliminary Experience of a Bulgarian Center

Takorov, Ivelin; Lukanova, Tsonka; Abrasheva, Maria; Arnaudov, Stefan; Simeonovski, Stefan; Vylcheva, Dimitria; Dimitrov, Dimitar; Stanimirov, Tsvetan

doi:10.21614/chirurgia.116.3.339

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Patients With Liver Transplantation and Covid-191

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2022

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“…A dose reduction of tacrolimus was undertaken following serum level evaluation without changing the dose of the mycophenolate mofetil for those on dual therapy. The case fatality rate was 33.3% as the patient with the severe disease died from respiratory failure[ 55 ]. Thus, elective liver transplantation was postponed at transplant centers in areas with high COVID-19 prevalence and limited resources to reduce the risk of infection and save resources[ 56 ].…”

Section: Patients With Liver Transplantation and Covid-19mentioning

confidence: 99%

Patterns of liver profile disturbance in patients with COVID-19

Shousha¹,

Ramadan²,

Lithy³

et al. 2022

WJCC

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Fever and cough are the most common clinical symptoms of coronavirus disease 2019 (COVID-19), but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in people with additional comorbidities. COVID-19 may be a new cause of liver disease, as liver profile disturbance is one of the most common findings among patients. The molecular mechanism underlying this phenomenon, however, is still unknown. In this paper, we review the most current research on the patterns of change in liver profile among patients with COVID-19, the possible explanation for these findings, and the relation to pre-existing liver disease in these patients.

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Section: Patients With Liver Transplantation and Covid-19mentioning

confidence: 99%