Covid-19 in Brazil: A sad scenario

Marinho, Pedro Rafael Diniz; Cordeiro, Gauss M.; Coêlho, Hemílio Fernandes Campos; Brandão, Simone Cristina Soares

doi:10.1016/j.cytogfr.2020.10.010

Cited by 34 publications

(37 citation statements)

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“…Em 2021, São Paulo, Rio de Janeiro, Ceará e Pernambuco ainda apresentam as maiores taxas de letalidade do Brasil. São Paulo lidera em número de casos desde o início, com aproximadamente 173% a mais de casos do que o Ceará (Neiva, Carvalho, Costa-Filho, Barbosa-Junior, Bernardi, Sanches et al, 2020;Marinho, Cordeiro, Coelho & Brandão, 2021).…”

Section: Resultsunclassified

“…Somente uma pequena porcentagem de brasileiros foi testada, ou por escassez de insumos, ou pelo alto custo dos exames. A reduzida testagem associada com a subnotificação torna a situação ainda mais preocupante, pois os países com as taxas mais altas de testes são considerados casos de sucesso na pandemia (Neiva, Carvalho, Costa-Filho, Barbosa-Junior, Bernardi, Sanches et al, 2020;Almeida, Pronunciate, Grotto, Pugliesi, Guimarães, Vilches et al, 2020;Ferreira, Almeida, Mattos & Oliveira, 2020;Sousa, Torres, Moura, Silva, Araújo, Sousa et al, 2020;Carvalho, Bochiero & Marson, 2021;Marinho, Cordeiro, Coelho & Brandão, 2021). Wang, Pan, Zhang, Fan, Han, Zhao et al (2020) destacam dois pontos para o controle do avanço da COVID-19: testar pacientes sem histórico de exposição e identificar pacientes infectados assintomáticos, considerando que a gravidade da doença pode ser reduzida com o diagnóstico e o atendimento médico-hospitalar precoce.…”

Section: Resultsunclassified

“…Tudo sugere que o Brasil reduziu as restrições prematuramente, considerando apenas os números de casos, sem analisar profundamente o sistema de atendimento de saúde local e, por esse motivo, pode enfrentar graves consequências em um futuro próximo. Na saúde pública, a prevenção é sempre a opção menos onerosa, principalmente neste caso, em que a resposta de um indivíduo à infecção pode ser a morte (Lobo, Cardoso-dos-Santos, Rocha, Pinheiro, Bremm, Macário, et al, 2020;Almeida, Pronunciate, Grotto, Pugliesi, Guimarães, Vilches et al, 2020;Neiva, Carvalho, Costa-Filho, Barbosa-Junior, Bernardi, Sanches et al, 2020;Dias, Pamplona, Rodrigues, Vogado, Silva-Júnior, Barreto et al, 2020;Marinho, Cordeiro, Coelho & Brandão, 2021).…”

Section: Resultsunclassified

“…Os números de casos e de mortes no início da pandemia, no Brasil, ainda não eram tão alarmantes, dando à população uma falsa sensação de segurança, o que pode ter influenciado na não adoção das medidas preventivas, mas, ainda hoje, as medidas preventivas são negligenciadas por muitos brasileiros, aumentando a disseminação do vírus (Almeida, Pronunciate, Grotto, Pugliesi, Guimarães, Vilches et al, 2020;Neiva, Carvalho, Costa-Filho, Barbosa-Junior, Bernardi, Sanches et al, 2020;Marinho, Cordeiro, Coelho & Brandão, 2021).…”

Section: Resultsunclassified

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Estudo infodemiológico da associação da pandemia da COVID-19 no Brasil com o volume de pesquisa na internet

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Mota

Sá

et al. 2021

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Verificar a existência de relação entre a busca por informação na Internet sobre COVID-19 e os números de casos e óbitos pela doença no território brasileiro. Realizamos um estudo infodemiológico usando a palavra de busca “Coronavírus” no Google Trends™, para cada unidade federativa e o Distrito Federal, referentes à população, ao número de casos confirmados e ao número de óbitos. Em seguida, comparamos cada Volume de Pesquisa Relativo ao número de novos casos e óbitos por COVID‑19 divulgados pelo Ministério da Saúde do Brasil durante o período de maio a junho de 2020. Os primeiros casos de COVID-19 notificados no país foram acompanhados do aumento de buscas na Internet sobre o tema, havendo uma redução do interesse ao longo do período estudado. A média de Volume de Pesquisa Relativo foi 37,8. Houve uma correlação positiva entre casos e óbitos, entretanto a correlação entre esses parâmetros e o Volume de Pesquisa Relativo comportou-se com significância negativa. Dados infodemiológicos têm permitido monitorar em tempo real surtos de doenças infecciosas em nível local e global. O Brasil apresentou comportamento inverso aos estudos anteriores. Evidenciamos uma forte relação negativa entre o acesso a conteúdo na Internet e o número de casos confirmados e óbitos por COVID-19 em todo o território brasileiro.

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Estudo infodemiológico da associação da pandemia da COVID-19 no Brasil com o volume de pesquisa na internet

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Sá

et al. 2021

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“…Brazil has one of the highest rates of COVID-19 cases and deaths in the world by so far. Since the beginning of 2020, the pandemic has had a great impact on the normal life of people in Latin America [2][3][4], including its largest country Brazil [5,6]. The COVID-19 pandemic not only threatens people's health but also impacts on the mental health of the public [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Depression and Anxiety Symptoms in Brazil during COVID-19

Zhang

Huang

et al. 2021

Preprint

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The COVID-19 pandemic in Brazil is extremely severe, and Brazil has the third-highest number of cases in the world. The goal of the study is to identify the prevalence rates and several predictors of depression and anxiety in Brazil during the initial outbreak of COVID-19. We surveyed 482 adults in 23 Brazilian states online on 9-22 May 2020, and found 70.3% of the adults (N=339) had depressive symptoms and 67.2% (N=320) had anxiety symptoms. The results of multi-class logistic regression models revealed that females, younger adults and those with fewer children had a higher likelihood of depression and anxiety symptoms; adults who worked as employees were more likely to have anxiety symptoms than those who were self-employed or unemployed; adults who spent more time browsing COVID-19 information online were more likely to have depression and anxiety symptoms. Our results provide preliminary evidence and early warning for psychiatrists and healthcare organizations to better identify and focus on the more vulnerable sub-populations in Brazil during the ongoing COVID-19 pandemic. Keywords: COVID-19; Brazil; anxiety; depression; predictors; risk factors

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Sociodemographic and clinical factors associated with poor COVID-19 outcomes in patients with rheumatic diseases: data from the SAR-COVID Registry

Isnardi¹,

Roberts²,

Quintana³

et al. 2022

Clin Rheumatol

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Background/objective This study aims to describe the course and to identify poor prognostic factors of SARS-CoV-2 infection in patients with rheumatic diseases. Methods Patients ≥ 18 years of age, with a rheumatic disease, who had confirmed SARS-CoV-2 infection were consecutively included by major rheumatology centers from Argentina, in the national, observational SAR-COVID registry between August 13, 2020 and July 31, 2021. Hospitalization, oxygen requirement, and death were considered poor COVID-19 outcomes. Results A total of 1915 patients were included. The most frequent rheumatic diseases were rheumatoid arthritis (42%) and systemic lupus erythematosus (16%). Comorbidities were reported in half of them (48%). Symptoms were reported by 95% of the patients, 28% were hospitalized, 8% were admitted to the intensive care unit (ICU), and 4% died due to COVID-19. During hospitalization, 9% required non-invasive mechanical ventilation (NIMV) or high flow oxygen devices and 17% invasive mechanical ventilation (IMV). In multivariate analysis models, using poor COVID-19 outcomes as dependent variables, older age, male gender, higher disease activity, treatment with glucocorticoids or rituximab, and the presence of at least one comorbidity and a greater number of them were associated with worse prognosis. In addition, patients with public health insurance and Mestizos were more likely to require hospitalization. Conclusions In addition to the known poor prognostic factors, in this cohort of patients with rheumatic diseases, high disease activity, and treatment with glucocorticoids and rituximab were associated with worse COVID-19 outcomes. Furthermore, patients with public health insurance and Mestizos were 44% and 39% more likely to be hospitalized, respectively. Study registration This study has been registered in ClinicalTrials.gov under the number NCT04568421. Key Points • High disease activity, and treatment with glucocorticoids and rituximab were associated with poor COVID-19 outcome in patients with rheumatic diseases. • Some socioeconomic factors related to social inequality, including non-Caucasian ethnicity and public health insurance, were associated with hospitalization due to COVID-19.

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Covid-19 in Brazil: A sad scenario

Cited by 34 publications

References 2 publications

Estudo infodemiológico da associação da pandemia da COVID-19 no Brasil com o volume de pesquisa na internet

Estudo infodemiológico da associação da pandemia da COVID-19 no Brasil com o volume de pesquisa na internet

Predictors of Depression and Anxiety Symptoms in Brazil during COVID-19

Sociodemographic and clinical factors associated with poor COVID-19 outcomes in patients with rheumatic diseases: data from the SAR-COVID Registry

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