COVID-19: Implications for bipolar disorder clinical care and research

Xue, Siqi; Ortiz, Abigail; Husain, Muhammad; Daskalakis, Zafiris J.; Mulsant, Benoit H.

doi:10.1177/2050312120981178

Cited by 14 publications

(8 citation statements)

References 41 publications

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“…The COVID-19 pandemic is an international public health crisis (WHO) with potentially significant implications for patients with psychiatric disorders (3)(4)(5)(6). We compared ED visits and inpatient occupancy rates between March 2019 and March 2020 and between the first and second half of March 2020 in the largest mental health hospital in Canada.…”

Section: Discussionmentioning

confidence: 99%

“…Within 2 months, over 316,000 deaths have been confirmed globally (WHO). Several recent papers have hypothesized that patients with psychiatric and/or substance use disorders may be particularly vulnerable to being infected with COVID-19 and to experience adverse outcomes, emphasizing the importance of studying the effect of this pandemic in this vulnerable population (2)(3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

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The Impact of COVID-19 on Psychiatric Emergency and Inpatient Services in the First Month of the Pandemic in a Large Urban Mental Health Hospital in Ontario, Canada

et al. 2021

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The World Health Organization characterized COVID-19 (coronavirus disease 2019) as a pandemic on March 11, 2020 (WHO). Within a couple of days, all Canadian provinces announced the implementation of social distancing measures. We evaluated the immediate effect of COVID-19 on psychiatric emergency and inpatient services in Canada's largest psychiatric hospital in the first month of the pandemic. We extracted data from the electronic medical records of the Center for Addiction and Mental Health in Toronto, Canada. We compared emergency department visits, inpatient occupancy rates, and length of stay in March 2019 and March 2020, and during the first and second half of March 2020. There was a decrease in the number of emergency department visits and inpatient occupancy rates in March 2020 compared to March 2019. There was also a significant decrease in the number of emergency department visits and inpatient occupancy rates in the second half of March 2020 compared to the first half. Our findings suggest that the pandemic was followed by a rapid decrease in the usage of psychiatric emergency and inpatient services in a large mental health hospital. Future studies will need to assess whether this decrease will be followed by a return to baseline or an increase in need for these services.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Impact of COVID-19 on Psychiatric Emergency and Inpatient Services in the First Month of the Pandemic in a Large Urban Mental Health Hospital in Ontario, Canada

et al. 2021

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“…The ongoing COVID-19 (coronavirus disease 2019) pandemic has had an overwhelming deleterious impact on the lives and care of people with severe mental illnesses – SMIs - including bipolar disorders – BDs ( Hernández-Gómez et al, 2021 ; Kozloff et al, 2020 ). For instance, social distancing regulations and lockdowns may decrease social support and increase loneliness ( Smith and Lim, 2020 ), and may also increase the risk of irregular social and circadian rhythms ( Murray et al, 2020 ; Xue et al, 2020 ). The burden posed by such downstream outcomes seems particularly relevant to vulnerable populations, such as people living with BD and related conditions.…”

Section: Introductionmentioning

confidence: 99%

Implications of the COVID-19 pandemic for people with bipolar disorders: A scoping review

Fornaro

Prisco

Billeci

et al. 2021

Journal of Affective Disorders

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Introduction The COVID-19 (coronavirus disease 2019)-related pandemic represents a global source of societal and health burden. Yet, the impact of the pandemic on people with severe mental illness, including bipolar disorder (BD), remains unclear, warranting scoping review on the matter. Methods The MEDLINE and EMBASE databases were systematically searched from inception up to April 24, 2021, adopting broad inclusion criteria to assess a variety of clinical and public health themes related to people with a primary diagnosis of BD during the COVID-19 pandemics. The present work complying with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) registered in the Open Science Framework (OSF) repository ( https://osf.io/7evpx/ ). Results Fourteen papers informed the present scoping review. Four major themes were identified: i) impact of COVID-19-related stressors on BD; ii) impact of COVID-19 on mental health service utilization among people with BD; iii) impact of BD on the risk of acquiring SARS-CoV-2 infection; iv) engagement in preventative behaviors among people with BD. Additional themes warranting further research were nonetheless detected. Limitations Further original studies are needed. Conclusion The present study confirmed the high-vulnerability hypothesis concerning people with BD versus the general population, reinforcing the need for further research related to the COVID-19 pandemic. Additional information is warranted to compare the impact of the pandemic period among BD people against pre-pandemic records, the general population, and other severe mental illnesses, namely people with schizophrenia or major depressive disorder, to inform the public health and the delivery of patient-tailored interventions.

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“…Some measures that have been adopted to curtail the spread of antine, may potentially disrupt both habitual sleep patterns and the number and on the risk of both manic and depressive relapses 3 . In this regard, recent studepisode, suggesting that the social isolation, lockdown and consequent lack of emotional support might introduce biorhythm dysregulation leading to higher vulnerability to depression 14,15 .…”

Section: Mood Disordersmentioning

confidence: 99%