COVID-19: Global Health Equity in Pandemic Response

Ivers, Louise C; Walton, David

doi:10.4269/ajtmh.20-0260

Cited by 44 publications

(56 citation statements)

References 4 publications

(3 reference statements)

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“…The decrease of lymphocyte which nally leads to immune disorder is due to the sustained responses of cytokines and chemokines (namely cytokine storm) caused by novel coronavirus [24][25][26] . The NLR was an important supplement for lymphocyte count, re ecting the in ammation of the patient which indicated the possibility of bacteria infection 9,27 .…”

Section: Discussionmentioning

confidence: 99%

“…Different countries have difference health resource. Even in the developed countries with enough health resource reserve, they may also confront the shortage of health resource and fail to response to COVID-19 pandemic 9 . By early screening, more current mild patients at risk of becoming severe can be arranged together for early intervention, and it also helps to make full use of health facilities and professionals.…”

Section: Discussionmentioning

confidence: 99%

“…What's more, some of these predictor were not early enough to prevent patients from becoming worse. It is very necessary to nd early simple predictors for quick risk assessment to screen more potential severe patients with COVID-19 and give them timely treatment to decrease the number of severe patients and death 1,[8][9][10][11] .…”

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confidence: 99%

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Early predictors and screening tool developing for severe patients with COVID-19

Fang

Xie

Liu

et al. 2020

Preprint

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Background Coronavirus disease 2019 (COVID-19) is a declared global pandemic, causing a lot of death. How to quickly screen risk population for severe patients is essential for decreasing the mortality. Methods This retrospective study included all the 813 confirmed cases diagnosed with COVID-19 before March 2nd, 2020 in a city of Hubei Province in China. Data of the COVID-19 patients including clinical and epidemiological features were collected through Chinese Disease Control and Prevention Information System. Predictors were selected by logistic regression, and then categoried to four different level risk factor. A screening tool for severe patient with COVID-19 was developed and tested by ROC curve. Results Seven early predictors for severe patients with COVID-19 were selected, including chronic kidney disease (OR=14.7), age above 60 (OR=5.6), lymphocyte count less than <0.8 × 109 per L (OR=2.5), Neutrophile to Lymphocyte Ratio larger than 4.7 (OR=2.2), high fever with temperature ≥38.5℃ (OR=2.2), male (OR=2.2), cardiovascular related diseases (OR=2.0). The Area Under the Curve of the screening tool developed by above seven predictors was 0.798 (95%CI: 0.747~0.849), and its best cut-off value is >4.5, with sensitivity 72.0% and specificity 75.3%. Conclusions This newly developed screening tool can be a good choice for early prediction and alert for severe case especially in the condition of overload health service.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Early predictors and screening tool developing for severe patients with COVID-19

Fang

Xie

Liu

et al. 2020

Preprint

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“…In conditions possibly even more severe than those in Idlib, before the pandemic Yemen was experiencing the world’s worst humanitarian crisis with 5 years of war leaving over 24 million people needing life-saving support. Since March 2020, low testing rates for COVID-19 in Yemen have made it extremely difficult to know exactly how many cases there are, let alone track, trace and isolate people with infection for effective control (Ivers and Walton 2020 ). One estimate suggests that up to 11 million people could be affected with some 72,000 deaths (Looi 2020 ).…”

Section: Dealing With Aggravated Environmental and Social Injusticementioning

confidence: 99%

The COVID-19 pandemic: local to global implications as perceived by urban ecologists

Douglas

Champion²,

Clancy

et al. 2020

Socio Ecol Pract Res

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The global COVID-19 pandemic is affecting everyone, but in many different ways, stimulating contrasting reactions and responses: opportunities for some, difficulties for many. A simple survey of how individual workers in urban ecology have been coping with COVID-19 constraints found divergent responses to COVID-19 on people’s activities, both within countries and between continents. Many academics felt frustrated at being unable to do fieldwork, but several saw opportunities to change ways of working and review their engagement with the natural world. Some engaging with social groups found new ways of sharing ideas and developing aspirations without face-to-face contact. Practitioners creating and managing urban greenspaces had to devise ways to work and travel while maintaining social distancing. Many feared severe funding impacts from changed local government priorities. Around the world, the COVID-19 pandemic has amplified issues, such as environmental injustice, disaster preparation and food security, that have been endemic in most countries across the global south in modern times. However, developing and sustaining the strong community spirit shown in many places will speed economic recovery and make cities more resilient against future geophysical and people-made disasters. Significantly, top-down responses and one-size-fits-all solutions, however good the modelling on which they are based, are unlikely to succeed without the insights that local knowledge and community understanding can bring. We all will have to look at disaster preparation in a more comprehensive, caring and consistent way in future.

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“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 (Zhu et al 2020), has been rapidly spreading and causing a worldwide pandemic (Kirby 2020;Saglietto et al 2020). The pneumonia induced by SARS-CoV-2 is known as coronavirus disease 2019 (Ivers and Walton 2020). To date, the virus has infected millions of people all over the world.…”

Section: Introductionmentioning

confidence: 99%

Patients with Prolonged Positivity of SARS-CoV-2 RNA Benefit from Convalescent Plasma Therapy: A Retrospective Study

Hong

Ruan

et al. 2020

Virol. Sin.

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Convalescent plasma therapy has been implemented in a few cases of severe coronavirus disease 2019. No report about convalescent plasma therapy in treating patients with prolonged positivity of SARS-CoV-2 RNA has been published. In this study, we conducted a retrospective observational study in 27 patients with prolonged positivity of SARS-CoV-2 RNA, the clinical benefit of convalescent plasma therapy were analyzed. qRT-PCR test of SARS-CoV-2 RNA turned negative (B 7 days) in a part of patients (early negative group, n = 15) after therapy, others (late negative group, n = 12) turned negative in more than 7 days. Pulmonary imaging improvement was confirmed in 7 patients in early negative group and 8 in late negative group after CP therapy. Viral load decreased in early negative group compared with late negative group at day 3, 5, 7 after implementing convalescent plasma therapy. Patients in early negative group had a shorter median length of hospital stay. In conclusion, convalescent plasma therapy might help eliminate virus and shorten length of hospital stay in patients with prolonged positivity of SARS-CoV-2 RNA.

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COVID-19: Global Health Equity in Pandemic Response

Cited by 44 publications

References 4 publications

Early predictors and screening tool developing for severe patients with COVID-19

Early predictors and screening tool developing for severe patients with COVID-19

The COVID-19 pandemic: local to global implications as perceived by urban ecologists

Patients with Prolonged Positivity of SARS-CoV-2 RNA Benefit from Convalescent Plasma Therapy: A Retrospective Study

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