COVID-19: From Emergence to Endemicity - A Comprehensive Review

Abstract

Severe Acute Respiratory Syndrome Coronavirus - 2 (SARS-CoV-2), later renamed Coronavirus Disease 2019 (COVID-19) was first identified in Wuhan, China, in early December 2019. Initially, the China office of the World Health Organization was informed of numerous cases of pneumonia of unidentified etiology in Wuhan, Hubei Province on December 31, 2019. This would subsequently result in a global pandemic with over 76 million confirmed cases of COVID-19 and 6.9 million deaths reported to the WHO. We have analyzed most of the data published since the beginning of the pandemic to compile this comprehensive review of SARS-CoV-2. We look at the core ideas, such as the etiology, epidemiology, pathogenesis, clinical symptoms, diagnostics, histopathologic findings, consequences, therapies, and vaccines. We have also included the long-term effects and myths associated with some therapeutics of COVID-19. This study comprehensively assesses of the SARS-CoV-2 virology, vaccines, medicines, and significant variants identified during the pandemic. Our review article is intended to provide medical practitioners with a better understanding of the fundamental sciences, clinical treatment, and prevention of COVID-19. As of June 2023, this paper contains the most recent data made accessible.

Unilateral foot drop due to prone positioning in COVID‐19: A case report

“…ARDS is diagnosed in about 33% of hospitalized COVID‐19 patients 1 and reported in about 10.8% of all COVID‐19‐related deaths 2 . Early PP has been noted to improve oxygenation and overall outcomes in patients with moderate to severe ARDS needing mechanical ventilation 3 and is associated with a lower incidence of intubation 4,5 …”