COVID-19: Eco-friendly hand hygiene for human and environmental safety

Daverey, Achlesh; Dutta, Kasturi

doi:10.1016/j.jece.2020.104754

Cited by 60 publications

(98 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, there are reports of E. coli (48%) and P. aeruginosa (64%) isolates resistant against all available sanitizers on the market [ 92 ]. Other reports also indicate that the excessive use of alcohol-based hand sanitizers in inpatient settings promotes resistant strains of pathogens [ 93 , 94 ]. Several pathogens, including E. coli , P. aeruginosa , B. cereus and Mycobacterium species, have shown tolerance and resistance to benzalkonium chloride.…”

Section: Personal Protective Equipment and Hygiene Practicesmentioning

confidence: 99%

“…Several pathogens, including E. coli , P. aeruginosa , B. cereus and Mycobacterium species, have shown tolerance and resistance to benzalkonium chloride. A cross-resistance between benzalkonium chloride and antibiotics has also been documented [ 94 , 95 ]. Moreover, the excessive use of surfactants, alcohol and hydrogen peroxides are also known to cause resistance in microorganisms [ 91 , 94 , 96 , 97 ].…”

Section: Personal Protective Equipment and Hygiene Practicesmentioning

confidence: 99%

See 1 more Smart Citation

Implications of COVID-19 Pandemic on the Emergence of Antimicrobial Resistance: Adjusting the Response to Future Outbreaks

Rušić

Vilović

Bukic

et al. 2021

Life

View full text Add to dashboard Cite

The net effect of the coronavirus disease 2019 (COVID-19) pandemic and the response to it on the emergence of antimicrobial resistance is yet unknown. Positive impacts on the spread of multiresistant pathogens and infections in general may be observed with the implementation of general preventative measures for the spread of infectious disease such as social distancing, reduced travel and increased personal hygiene. This pandemic has accelerated the development of novel technologies, such as mRNA vaccines, that may be used to fight other diseases. These should be capitalized upon to manage the ongoing antimicrobial resistance pandemic in the background. However, it is likely that the COVID-19 pandemic is fueling the emergence of antimicrobial resistance due to high rates of inappropriate antimicrobial prescribing, the high use of biocides and the interruption of treatment for other conditions. Clinical uncertainty driven by the lack of effective diagnostics and practice of telemedicine may have driven the inappropriate use of antimicrobials. As pathogens know no borders, increased focus is needed for infectious diseases still threatening low- and middle-income countries such as tuberculosis. Stewardship measures for future outbreaks should stress the importance of social distancing and hand washing but discourage the overuse of disinfectants and antimicrobials that are not proven effective.

show abstract

Section: Personal Protective Equipment and Hygiene Practicesmentioning

confidence: 99%

Section: Personal Protective Equipment and Hygiene Practicesmentioning

confidence: 99%

Implications of COVID-19 Pandemic on the Emergence of Antimicrobial Resistance: Adjusting the Response to Future Outbreaks

Rušić

Vilović

Bukic

et al. 2021

Life

View full text Add to dashboard Cite

show abstract

“…Alcohols are known to possess broad-spectrum antimicrobial activity against bacteria, fungi and viruses. While the specific mechanism of action of alcohols is not clear, it is thought to be related to denaturation of membrane and enzymatic proteins [ 6 , 7 , 8 ].…”

Section: Faces Of the Tetrahedron: Inputsmentioning

confidence: 99%

Alcohol-Based Hand Sanitizers in COVID-19 Prevention: A Multidimensional Perspective

Abuga

Nyamweya²

2021

Pharmacy

View full text Add to dashboard Cite

The global use of alcohol-based hand sanitizers (ABHS) as an important means of controlling the transmission of infectious disease has increased significantly as governments and public health agencies across the world advocated hand hygiene as a preventative measure during the COVID-19 pandemic. Although the performance of these products is most commonly defined as a function of their alcohol concentration, they are multifaceted products in which an interplay of several factors is important in determining efficacy. This paper discusses the interplay between ABHS input (formulation) factors and output (product performance) factors in the context of a multidimensional perspective using a novel representative paradigm. In the model, represented in the form of a three-dimensional tetrahedron, each of the faces represents inputs in the manufacturing of the ABHS product, which are the type and amount of alcohol, the inactive ingredients, the formulation and the manufacturing practices. The four corners of the tetrahedron represent the product performance factors which include product efficacy, sensory characteristics, usage and compliance and product safety. The multidimensional approach to the formulation and evaluation of ABHS shows that several factors contribute to the effectiveness and utility of these products. The paradigm provides a useful framework for manufacturers of ABHS and related healthcare products.

show abstract

“…The ongoing use of petrochemical surfactants in hand hygiene solutions and soaps has raised concerns of environmental contamination, further supporting the search for biodegradable plant-based solutions. 85…”

Section: Plant Based Sanitisersmentioning

confidence: 99%

“…86 When looking at plant constituents, saponins are the most widely studied plant-based surfactants. 85 Saponins from Quillaja saponaria have been shown to poses antiviral activity against numerous viral species including HIV. Bupleurum marginatum and Parispolyphylla are effective against influenza A and the saikosaponin constituents of Bupleurum marginatum have demonstrated coronavirus activity.…”

Section: Existing Data On Plant Based Sanitisersmentioning

confidence: 99%

The 2020 Coronavirus (COVID-19) Global Pandemic, a Call to Arms to Pharmacognosy Researchers – Plant-Based Antiviral Approaches

Alcorn¹

2021

View full text Add to dashboard Cite

Background:The unprecedented modern pandemic that is COVID-19 has awakened a global fear of viral disease and an activation of viral targeted drug discovery not seen before in modern times. Whilst the vaccines about to enter the market, are an important component of the strategy to combat COVID-19, vaccination should be considered a part of a wider strategy to address this and future zoonotic viral outbreaks. Plant-based approaches may provide valuable avenues for viral disease management. Methods: This commentary combines an appraisal of the existing literature with the authors thoughts on key challenges that pharmacognosy may be able to assist with, in the management of zoonotic viral disease. Results: There are many avenues for plant-based antiviral research in the context of the present COVID-19 pandemic. This narrative review discusses the use of plant-based approaches; as viral drug leads, as agents for managing the cytokine storm associated with acute respiratory distress syndrome, as agents for elimination of viral reservoirs and as agents in hand sanitisation. Conclusion: Whilst the arrival of vaccines is an important step in the response to the current COVID-19 pandemic. Pharmacognosy still has a role to play in the management of this and future viral pandemics. The support of researchers in this domain is needed to combat viral pandemics via arming clinicians with a broader range of options for prevention and treatment of viral illness on a global scale.

show abstract

COVID-19: Eco-friendly hand hygiene for human and environmental safety

Cited by 60 publications

References 46 publications

Implications of COVID-19 Pandemic on the Emergence of Antimicrobial Resistance: Adjusting the Response to Future Outbreaks

Implications of COVID-19 Pandemic on the Emergence of Antimicrobial Resistance: Adjusting the Response to Future Outbreaks

Alcohol-Based Hand Sanitizers in COVID-19 Prevention: A Multidimensional Perspective

The 2020 Coronavirus (COVID-19) Global Pandemic, a Call to Arms to Pharmacognosy Researchers – Plant-Based Antiviral Approaches

Contact Info

Product

Resources

About