COVID-19 Crisis Management: Lessons From the United Arab Emirates Leaders

Zaher, Walid; Ahamed, Faheem; Ganesan, Subhashini; Warren, Katherine; Koshy, Ashish

doi:10.3389/fpubh.2021.724494

Cited by 23 publications

(28 citation statements)

References 3 publications

(4 reference statements)

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“…In summary, this study lays the foundation for future studies to bridge the gap between the polymorphisms and their possible involvement in the dysregulation of ACE2 in COVID-19. A limitation to our study includes the lack control samples (non-COVID-19) due to the difficulty in achieving patients’ samples that were not vaccinated, as vaccination process in the United Arab Emirates (UAE) has been initiated effectively by treated all people as emergency patients 36 , 37 . Moreover, additional information regarding demographic and pre-existing conditions such as smoking status for each patient were not provided.…”

Section: Discussionmentioning

confidence: 99%

ACE2 polymorphisms impact COVID-19 severity in obese patients

Jalaleddine

Bouzid

Hachim

et al. 2022

Sci Rep

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A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. The expression of angiotensin converting enzyme 2 (ACE2), the main receptor for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is enhanced in obese individuals. The occurrence of frequent genetic single nucleotide polymorphisms (SNPs) in ACE2 is suggested to increase COVID-19 severity. Accordingly, we hypothesize that obesity-associated ACE2 polymorphisms increase the severity of COVID-19. In this study, we profiled eight frequently reported ACE2 SNPs in a cohort of lean and obese COVID-19 patients (n = 82). We highlight the significant association of rs2285666, rs2048683, rs879922, and rs4240157 with increased severity in obese COVID-19 patients as compared to lean counterparts. These co-morbid-associated SNPs tend to positively correlate, hence proposing possible functional cooperation to ACE2 regulation. In obese COVID-19 patients, rs2285666, rs879922, and rs4240157 are significantly associated with increased blood nitrogen urea and creatinine levels. In conclusion, we highlight the contribution of ACE2 SNPs in enhancing COVID-19 severity in obese individuals. The results from this study provide a basis for further investigations required to shed light on the underlying mechanisms of COVID-19 associated SNPs in COVID-19 obese patients.

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Section: Discussionmentioning

confidence: 99%

ACE2 polymorphisms impact COVID-19 severity in obese patients

Jalaleddine

Bouzid

Hachim

et al. 2022

Sci Rep

View full text Add to dashboard Cite

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“…While readmission rates for the reported HMP-O 2 are higher than overall readmissions for COVID-19 patients not involved in an HMP (here, 35% vs. 4–20%; Gavin et al, 2021 ), they are similar to the 25% readmission rate reported by Llorens et al for a home health program that directly discharged mild COVID-19 from the ED. Notably, that program reported a 77% cost-savings for these patients ( Abbas Zaher et al, 2021 ), but did not include patients requiring oxygen ( Llorens et al, 2021 ). Other hospitals developed a hybrid model, Atrium Health provided virtual monitoring for mild patients and in-person appointments for moderate to severe patients that would normally be in the hospital ( Sitammagari et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

Hospital Days Reduced for Moderate and Severe COVID-19 Patients Through a Home Monitoring Program With Oxygen

Martinez

Ehsan²,

Mellady

et al. 2023

Clin Nurs Res

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While the COVID-19 pandemic continues to strain the healthcare system, it has also expanded telemedicine. There is a subset of hospitalized moderate to severe COVID-19 patients requiring oxygen but no other intervention. This is a retrospective study of patients ≥18 years with moderate to severe COVID-19 that participated in a home monitoring program with supplemental oxygen (HMP-O2) ( N = 25). For study outcomes, HMP-O2 participants were compared to patients meeting the same inclusion criteria but did not participate in the program ( N = 60). On average, the HMP-O2 patients spent 5.8 days (±5.5 days) in the hospital compared to 8.12 days (±5.5 days) for non-program patients. This resulted in 19% cost-savings for HMP-O2 patients. Lessons learned from this program can be applied to future HMPs for either COVID-19 or other conditions that would benefit from telecare.

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“…Future interventions focused on rest and social support for healthcare workers can be implemented as explained in the systemic review [27]. Abu Dhabi was rated among the best-performing cities in the world regarding the preparedness and supportive measures among them, including the healthcare system [29]. Nevertheless, the mental health of the healthcare workers seems an area worth investing in with the high depression and anxiety found.…”

Section: Plos Onementioning

confidence: 99%

Impact of COVID-19 on depression and anxiety among healthcare professionals in Abu Dhabi

et al. 2023

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Background COVID-19 has affected Healthcare workers in many ways. One of the important areas is the psychological impact. This study aims to examine the effects of the COVID-19 outbreak on the mental health of Healthcare Professionals (HCP) and associated factors. Methods A cross-sectional study was conducted among healthcare providers in the Emirates of Abu Dhabi, United Arab Emirates, between April 11th, and July 23rd, 2020. The study was conducted by using an online anonymous Self-administered questionnaire through the survey monkey platform. A convenient sampling method was used to distribute the online survey link through the organization’s email network admin list and smartphone messaging. Descriptive statistics, t-tests, and multivariant linear regression were used. Results Anxiety and depression risk scores were measured in a total of 1268 participants of healthcare providers. More than half of the participants reported symptoms of anxiety (51.5%). Depression symptoms were revealed in 38.3% of participating providers. A mild risk of anxiety was reported in 28.8% of the participants and 12.68% of the participants registered moderate anxiety risk scores and 9.95% reported a severe risk of anxiety. Among all participants, 4.3% and 2.7% reported moderately severe and severe risk of depression, respectively, while 22.5% and 8.8% of the participating healthcare providers documented mild and moderate depression risk. Anxiety and depression risk scores were significantly and negatively associated with age and working in primary health care. Conclusions The high prevalence of anxiety and depression recorded among HCP during the pandemic suggests that mental health intervention and support are necessary to ensure the psychological well-being of HCP.

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COVID-19 Crisis Management: Lessons From the United Arab Emirates Leaders

Cited by 23 publications

References 3 publications

ACE2 polymorphisms impact COVID-19 severity in obese patients

ACE2 polymorphisms impact COVID-19 severity in obese patients

Hospital Days Reduced for Moderate and Severe COVID-19 Patients Through a Home Monitoring Program With Oxygen

Impact of COVID-19 on depression and anxiety among healthcare professionals in Abu Dhabi

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