COVID-19 Causing Hypotension in Frail Geriatric Hypertensive Patients?

Koudelka, Marek; Sovová, Eliška

doi:10.3390/medicina57060633

Cited by 9 publications

(14 citation statements)

References 20 publications

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“…Koudelka et al reported the cases of five frail geriatric patients with sarcopenia and controlled hypertension who became hypotensive after COVID infection. They found that the previously well-established therapy was suddenly too intensive for those patients [43] .…”

Section: Discussionmentioning

confidence: 99%

The significant impact of Coronavirus disease 2019 (COVID-19) on in-hospital mortality of elderly patients with moderate to severe traumatic brain injury: A retrospective observational study

Bagheri

Abdi

Benson

et al. 2021

Journal of Clinical Neuroscience

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Background Traumatic brain injury (TBI) is one of the main causes of death and disability among the elderly patient population. This study aimed to assess the predictors of in-hospital mortality of elderly patients with moderate to severe TBI who presented during the Coronavirus disease 2019 (COVID-19) pandemic. Methods In this retrospective analytical study, all elderly patients with moderate to severe TBI who were referred to our center between March 2nd, 2020 to August 1st, 2020 were investigated and compared against the TBI patients receiving treatment during the same time period within the year 2019. Patients were followed until discharge from the hospital or death. The demographic, clinical, radiological, and laboratory test data were evaluated. Data were analyzed using SPSS-21 software. Findings In this study, 359 elderly patients were evaluated ( n = 162, Post-COVID-19). Fifty-four patients of the cohort had COVID-19 disease with a mortality rate was 33.3%. The patients with COVID-19 were 5.45 times more likely to expire before discharge (P < 0.001) than the TBI patients who were not COVID-19 positive. Other variables such as hypotension (OR, 4.57P < 0.001), hyperglycemia (OR, 2.39, P = 0.002), and use of anticoagulant drugs (OR, 2.41P = 0.001) were also associated with in-hospital death. According to the binary logistic regression analysis Age (OR, 1.72; 95% CI: 1.26–2.18; P = 0.033), Coronavirus infection (OR, 2.21; 95% CI: 1.83–2.92; P = 0.011) and Glasgow Coma Scale (GCS) (OR, 3.11; 95% CI: 2.12–4.53; P < 0.001) were independent risk factors correlated with increased risk of in-hospital mortality of elderly patients with moderate to severe TBI. Conclusion Our results showed that Coronavirus infection could increase the risk of in-hospital mortality of elderly patients with moderate to severe TBI significantly.

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Section: Discussionmentioning

confidence: 99%

The significant impact of Coronavirus disease 2019 (COVID-19) on in-hospital mortality of elderly patients with moderate to severe traumatic brain injury: A retrospective observational study

Bagheri

Abdi

Benson

et al. 2021

Journal of Clinical Neuroscience

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“…The elderly are a group at high risk of being infected with Covid 19 because they have a decreased immune system which makes it easier for the virus to attack the respiratory system (Venugopal et al, 2020). In addition, the elderly also have an increased risk of getting Covid 19 because they have comorbidities (Viro et al, 2021), for example, disorders of the cardiovascular system such as hypertension (Koudelka & Sovová, 2021). The prevalence of hypertension increases with age which affects more than 50% of the elderly aged 60 years (Pan et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

The Impact of Effleurage Technique Massage on Blood Pressure toward Elderly Hypertension in Peguyangan Village

Astuti¹,

Wisnawa²,

Astawa

2022

nhs

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Background: One of the vulnerable groups is elderly. Entering the aging process, the elderly will have a decrease a physiological disfunction which make some of non-spreadable disease appear such as hypertension. In this critical situation, a solution is needed to tackling hypertension. One of the non-pharmacological therapy that can be handle for hypertension is effleurage massage. Aim: The aim of this study is to determine the effect of effleurage technique massage on blood pressure toward elderly hypertension at Peguyangan Village. Method: This study is use a quantitative method with quasy experimental design which research design of pre-post-test control design. Sample of this study were 15 respondents in every group. This massage therapy using effleurage massage technique during 20 minutes while control group rest for 20 minutes. Technique sample is using a purposive sampling. Data analysis with Wilcoxon Rank Test with Significance level α <0,05 from the result in the treatment group shows that the p value (sig). Conclusion: The massage of effleurage technique for 20 minutes affects toward lowering blood pressure in the elderly hypertension but resting for 20 minutes has not significantly on the reducing of hypertension blood pressure in elderly.

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“…Poor BP control status was also independently associated with higher risk. However, a recent study comparing BP < 130 mmHg with <140 mmHg reported that patients with BP < 130 mmHg treated with COVID-19 were associated with higher mortality, especially in geriatric patients [ 6 – 8 ] In the end, how is the BP target in COVID-19 patients still unclear.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic target and clinical impact of day-to-day blood pressure variability in hypertensive patients with covid-19

et al. 2022

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Blood pressure variability (BPV) is essential in hypertensive patients and is frequently associated with organ damage. As of today, hypertension is still the most common comorbidity in COVID-19, but the impact of BPV and the therapeutic target of BPV on outcomes in COVID-19 patients with hypertension remain unclear. Therefore, this study investigated the relationship between BPV and severity of COVID-19, in-hospital mortality, hypertensive status, and efficacy of antihypertensives in suppressing hypertensive covid-19 patient BPV. This cohort retrospective study enrolled 351 patients hospitalized with COVID-19. Subjects were classified according to the severity of COVID-19, the presence of hypertension, and their BPV status. During hospitalization, mean arterial pressure (MAP) was measured at 6 a.m. and 6 p.m., and BPV was calculated as the coefficient of variation of MAP (MAPCV). MAPCV values above the median were defined as high BPV. In addition, we compared the hypertensive status, COVID-19 severity, in-hospital mortality, and antihypertensive agents between the BPV groups. The mean age was 53.85 ± 18.84 years old. Hypertension was significantly associated with high BPV with prevalence ratio (PR) = 1.38 (95% CI = 1.13–1.70; p = 0.003) or severe COVID-19 (PR = 1.39; 95% CI = 1.09–1.76; p = 0.005). In laboratory findings, high BPV group had lower Albumin, higher WBC, serum Cr, CRP, and creatinine to albumin ratio. High BPV status also significantly increased risk of mortality (HR = 2.30; 95% CI = 1.73–3.86; p < 0.001). Patients with a combination of severe COVID-19 status, hypertension, and high BPV status had the highest risk of in-hospital mortality (HR = 3.51; 95% CI = 2.32–4.97; p < 0.001) compared to other combination status groups. In COVID-19 patients with hypertension, combination therapy with calcium channel blockers (CCB) as well as CCB monotherapy significantly develop low BPV (PR = 2.002; 95 CI% = 1.33–3.07; p = 0.004) and low mortality (HR = 0.17; 95% CI = 0.05–0.56; p = 0.004). Hypertensive status and severe COVID-19 were significantly associated with high BPV, and these factors increased in-hospital mortality. CCBs might be antihypertensive agents that potentially effectively suppressing BPV and mortality in COVID-19 patients.

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COVID-19 Causing Hypotension in Frail Geriatric Hypertensive Patients?

Cited by 9 publications

References 20 publications

The significant impact of Coronavirus disease 2019 (COVID-19) on in-hospital mortality of elderly patients with moderate to severe traumatic brain injury: A retrospective observational study

The significant impact of Coronavirus disease 2019 (COVID-19) on in-hospital mortality of elderly patients with moderate to severe traumatic brain injury: A retrospective observational study

The Impact of Effleurage Technique Massage on Blood Pressure toward Elderly Hypertension in Peguyangan Village

Therapeutic target and clinical impact of day-to-day blood pressure variability in hypertensive patients with covid-19

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