The handling of genetic residues, biohazardous waste, and other non-shrinkable materials such as e-waste is essential for the preservation of Mother Nature and human wellbeing. This chapter will bring forth different methods of managing biomedical wastes, inspecting the roots of the spread of the hazardous virus, and protecting the front-line warriors. To properly react to this disaster, each administration must create a backup strategy based on regional circumstances and the seriousness of the coronavirus's spread. Technology is being used to reduce the need for in-person medical appointments and save on the cost of treatment, which is a boon for human civilization in the context of the pandemic. The Central Pollution Control Board's existing rules provide a framework for managing healthcare waste with respect for the safety of the public. Bio-waste management strategies using IoT and IoMT techniques are illustrated in this chapter.