COVID-19 Associated Inference of Cycle Threshold (Ct) Value by RT-PCR: A Rapid Review

Abstract

Currently, all SARS-CoV-2 detection measures make use of RT-PCR test, and its results are generally reported as either positive or negative, which tells us if a person is infected. However, to contain the pandemic, what we need to know is whether that person is infectious or in other words, 'can he spread the disease?' It's critical to know that the RT-PCR test does give an extra degree of the viral load within the test. This perusing is called the cycle threshold (Ct) value. [1] Prove recommends that detailing this Ct value (calculated viral load) can help in a higher elucidation of the condition, additionally in taking clinical choices. The conclusion, screening, and reconnaissance depend on an extremely intense respiratory disorder coronavirus 2 (SARS-CoV-2) reverse transcriptase polymerase chain response (RT-qPCR) tests, and comes about being for the most part detailed to the requesting physician as positive or negative. [2] In any case, the test does give a degree of the viral load within the test, in what is called the cycle threshold (Ct) value. Through this article we suggest guidelines which announcing this Ct value, or a calculated viral load, can help in the elucidation and clinical choices in conjunction with its importance and interference.