COVID-19-associated diarrhea

Щикота, А. М.; Погонченкова, И. В.; Турова, Е А; Starodubova, A. V.; Nosova, N.V.

doi:10.33029/0042-8833-2021-90-6-18-30

Cited by 5 publications

(2 citation statements)

References 4 publications

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“…Despite the international community emphasis on reasonable antibacterial intervention for COVID-19 patients, clinical practice often deviates from this principle, resulting in an upsurge risk of developing antibiotic-induced acute diarrhea. Antibacterial treatment should be reserved for cases with clear evidence of bacterial infection (phlegm, procalcitonin, leukopenia and neutropenia) ( Shchikota et al, 2021 ). Traditional Chinese medicine (TCM) has been reported to reduce the risk of mild and severe cases of COVID-19 developing to critical stages and significantly shorten the course of disease and improve overall clinical effectiveness ( Liu et al, 2020 ).…”

Section: Preventive Measures For Long-term Gi Injury Induced By Sars-...mentioning

confidence: 99%

Development and management of gastrointestinal symptoms in long-term COVID-19

He,

Lei,

Zhang

et al. 2023

Front. Microbiol.

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BackgroundEmerging evidence reveals that SARS-CoV-2 possesses the capability to disrupt the gastrointestinal (GI) homeostasis, resulting in the long-term symptoms such as loss of appetite, diarrhea, gastroesophageal reflux, and nausea. In the current review, we summarized recent reports regarding the long-term effects of COVID-19 (long COVID) on the gastrointestine.ObjectiveTo provide a narrative review of abundant clinical evidence regarding the development and management of long-term GI symptoms in COVID-19 patients.ResultsLong-term persistent digestive symptoms are exhibited in a majority of long-COVID patients. SARS-CoV-2 infection of intestinal epithelial cells, cytokine storm, gut dysbiosis, therapeutic drugs, psychological factors and exacerbation of primary underlying diseases lead to long-term GI symptoms in COVID-19 patients. Interventions like probiotics, prebiotics, fecal microbiota transplantation, and antibiotics are proved to be beneficial in preserving intestinal microecological homeostasis and alleviating GI symptoms.ConclusionTimely diagnosis and treatment of GI symptoms in long-COVID patients hold great significance as they may contribute to the mitigation of severe conditions and ultimately lead to the improvement of outcomes of the patients.

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Section: Preventive Measures For Long-term Gi Injury Induced By Sars-...mentioning

confidence: 99%

Development and management of gastrointestinal symptoms in long-term COVID-19

He,

Lei,

Zhang

et al. 2023

Front. Microbiol.

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“…Antibiotics, in particular, cause antibiotic-associated diarrhea [76]. Although the international community calls for the most reasonable antibacterial intervention for COVID-19 patients, antibacterial treatment should only be performed when there is obvious bacterial infection (phlegm, procalcitonin, leukopenia and neutropenia), but this principle is often violated in actual clinical practice, which easily causes antibiotic-associated diarrhea [77].…”

Section: Rational Medicationmentioning

confidence: 99%

Long-term impacts of SARS-CoV-2 on gastrointestinal tract

Lü

et al. 2023

Preprint

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COVID-19 from SARS-CoV-2 has caused a large number of infections and deaths. COVID-19 is a respiratory infectious disease caused by the combination of SARS-CoV-2 with angiotensin converting enzyme 2 (ACE2) receptor into the target organ of the host. COVID-19 patients not only have respiratory symptoms, but also some patients with symptoms such as nausea, abdominal pain, and diarrhea. Even a few patients have atypical symptoms such as diarrhea as the first manifestation, indicating that the severity of COVID-19 patients is closely related to gastrointestinal symptoms. There is currently rare researches on long-term gastrointestinal adverse impacts in patients with COVID-19. We will summarize the etiology, epidemiology and pathogenic mechanism of SARS-CoV-2 as well as the digestive system symptoms and targeted treatment of COVID-19, so as to increase the insight of the long-term gastrointestinal injury caused by SARS-CoV-2, thereby providing new therapeutic strategies and targets for gastrointestinal injury.

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Early diagnosis and predicting of acute kidney injury in children with viral gastroenteritis of various agents (Literature review)

Mazankova,

Luzan

2023

Det. infekc.

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The most common viral infections causing gastroenteritis in children include rotavirus, norovirus, and the SARS-CoV-2. A typical clinical picture includes fever, vomiting, diarrhea, toxicosis and exicosis of varying severity. However, in 30—35% of cases, acute intestinal infections of viral etiology complicate of acute kidney injury (AKI), which significantly aggravates the course of the disease and affects the outcome of the disease. Currently used markers for the diagnosis of AKI are poor informative due to late detection of typical laboratory changes during the clinical picture's change. Currently, there are non-invasive biomarkers of AKI detected before changes in routine biochemical tests and can be used for early diagnosis of kidney damage. Using of these biomarkers in practice will develop of clinical and laboratory differential diagnostic criteria for early diagnosis, risk factors for the development of AKI in children with viral diarrhea of various agents, in order to start timely effective pathogenetic treatment and prevent serious complications.

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COVID-19-associated diarrhea

Cited by 5 publications

References 4 publications

Development and management of gastrointestinal symptoms in long-term COVID-19

Development and management of gastrointestinal symptoms in long-term COVID-19

Long-term impacts of SARS-CoV-2 on gastrointestinal tract

Early diagnosis and predicting of acute kidney injury in children with viral gastroenteritis of various agents (Literature review)

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