COVID-19 and the Unraveling of Experimental Medicine - Part III

Thorp, K. E.; Thorp, James A.; Thorp, Elise M.

doi:10.46766/thegms.pubheal.22042302

Cited by 6 publications

(6 citation statements)

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“…This manuscript published and categorized these 1,366 articles with the most common categories being myocarditis/pericarditis in 336 articles, vaccine-induced thrombotic thrombocytopenia in 209 articles, and 160 articles regarding arterial and venous thromboembolism. [33] There are many strengths of this study. The open-source VAERS database used for this investigation is regulated, owned, and maintained by the CDC/FDA.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccines: A Risk Factor for Cerebral Thrombotic Syndromes

Rogers,

Thorp,

Cosgrove

et al. 2024

Preprint

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Introduction: This population-based retrospective cohort study assesses rates of adverse events (AEs) involving cerebral thromboembolism (CTE) after COVID-19 vaccines. Methods: Data were collected from the U.S. Centers for Disease Control and Prevention (CDC) and Food and Drug Administration (FDA) Vaccine Adverse Event Reporting System (VAERS) database from January 1, 1990 to December 31, 2023. CTE AEs after COVID-19 vaccines were compared to those after influenza vaccines and after all other vaccines using proportional reporting ratio (PRR) analysis by time. Results: There are 5137 cerebral thromboembolism AEs reported in the 3 years (36 months) after COVID-19 vaccines compared to 52 AEs for the influenza vaccines over the past 34 years (408 months) and 282 AEs for all other vaccines (excluding COVID-19) over the past 34 years (408 months). The PRR’s are significant when comparing AEs by time from COVID-19 vaccines to that of the influenza vaccines (p < 0.0001) or to that of all other vaccines (p < 0.0001). The CTE AEs PRR by time (95% confidence intervals) for the COVID-19 vaccine AEs vs influenza AEs is 1120 (95% confidence interval (723-1730), p < 0.0001) and for COVID-19 vaccines vs all others is 207 (95% confidence interval (144-296), p < 0.0001). Cerebral venous thromboembolism AEs are female predominant with a female/male odds ratio of 1.63 (95% confidence interval (1.52-1.74), p < 0.0001). Conversely, cerebral arterial thromboembolism has a nonsignificant male preponderance. Cerebral venous thromboembolism is far more common than cerebral arterial thromboembolism over 36 months with an odds ratio (OR) of 14.8 (95% confidence interval 14.0-15.5, p < 0.0001). Atrial fibrillation, the most common identifiable cause of cerebral venous thromboembolism, occurs far more commonly after the COVID-19 as compared to all other vaccines with a PRR of 123 (95% CI 88.3-172, p < 0.0001) Conclusions: There is an alarming breach in the safety signal threshold concerning cerebral thrombosis AEs after COVID-19 vaccines compared to that of the influenza vaccines and even when compared to that of all other vaccines. An immediate global moratorium on the use of COVID-19 vaccines is necessary with an absolute contraindication in women of reproductive age.

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Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccines: A Risk Factor for Cerebral Thrombotic Syndromes

Rogers,

Thorp,

Cosgrove

et al. 2024

Preprint

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“…It is difficult to explain these results on any basis other than primary failure of containment and vaccine strategies. [34][35][36] The failure to significantly impact pandemic outcomes incriminates top-down centralized management strategies by entities such as WHO and large countries like the US. In March 2020, WHO Director-General Ghebreysus announced "we have a simple message for all countries: test, test, test."…”

Section: Discussionmentioning

confidence: 99%

Global COVID-19 Pandemic Outcomes: Dissecting a Failed Strategy

Thorp¹,

Thorp²,

Thorp³

et al. 2022

Preprint

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Objectives to assess COVID-19 mortality rates per country population. To determine what if any independent country-specific variables from 9 different databases were correlated. Design population based retrospective cohort study. Setting analysis of global COVID-19 treatment and containment strategies using data from 9 worldwide websites. Participants 108 countries worldwide. Interventions none. Main Outcome Measures were COVID-19 death rates per country population analyzed by univariate and multivariate analysis. The main outcome parameters were to determine if there are any correlations between the percentage of countrywide COVID-19 deaths/population by the countries’ percent vaccinated. Secondary outcome measures include the effect of other independent variables on COVID-19 death rates per country population including: health expenditures per capita, annual income per capita, COVID-19 tests per 1000 people, stringency index (a measure of each countries containment strategies), hydroxychloroquine score (a measure of each countries use), ivermectin score (a measure of each countries use), hypertension, obesity, diabetes, and specific countries and geographic locations. Results COVID-19 vaccination rates ranged from 0-99% in 108 countries. Univariate analysis demonstrates the following independent variables to correlate with COVID-19 deaths/population (correlation coefficient, p value): countrywide COVID-19 vaccination rates (+0.2936, p=0.002); healthcare costs per capita (+0.3212, p=0.0007), income per capita (+0.3051, p=0.0013), COVID-19 tests per 1000 population (+0.6981 p=0.0307); stringency index (+0.3098, p=0.0011); hydroxychloroquine index (-0.1337, p=0.0678); and ivermectin index (-0.1383, p=0.1535). Conclusions Increasing rates of COVID-19 vaccination are associated with increase COVID-19 death rates per country population (p=0.002). Other variables associated include healthcare costs per capita (+0.3212, p=0.0007), income per capita (+0.3051, p=0.0013), COVID-19 tests per 1000 population (+0.6981 p=0.0307); and stringency index (+0.3098, p=0.0011).

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“…Public perception of evolving pandemic events was actively manipulated by disinformation originating in governmental agencies such as the HHS, NIH, FDA and CDC while mainstream media outlets and social media platforms labeled valid dissenting perspectives as misinformation. As shown in earlier work, 80-90% of the COVID-19related deaths were preventable had appropriate treatments been implemented [8][9][10]. While many scientists endorsed the opportunistic agenda, even propping it up with partisan research, a large and growing body of evidence indicates that the corporatist pandemic strategy utterly failed to achieve its stated goals.…”

Section: Introductionmentioning

confidence: 95%