Covid-19 and Pregnancy: An Overview

Castro, Priscila da Silva; Matos, Areolino Pena; Werner, Heron; Lopes, Flávia Paiva Proença Lobo; Tonni, Gabriele; Júnior, Edward Araujo

doi:10.1055/s-0040-1713408

Cited by 49 publications

(47 citation statements)

References 54 publications

(62 reference statements)

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“…The neonate should be dried, cleaned, disinfected, and taken to an isolation room, with a swamp sample being already acquired for qRT-PCR testing [ 8 ]. The absence of mother-to-neonate transmission evidence has generated controversies with regard to maternal and neonatal separation.…”

Section: Resultsmentioning

confidence: 99%

“…Anatomic, physiologic, and immunologic changes during pregnancy are considered to pose a risk for severe COVID-19 infection and disease, as was previously experienced with the H1N1 pandemic [ 5 , 6 , 7 ]. Increased maternal oxygen demand, elevated diagram, and edema of the respiratory mucosa during pregnancy decrease the maternal tolerance of hypoxia [ 8 ]. Therefore, pregnant women could be more likely to develop a more severe respiratory status (in the case of a viral pneumonia, which happened in the outbreak of H1N1, SARS-CoV-1, and middle east respiratory syndrome coronavirus (MERS-CoV)) [ 1 , 2 , 3 , 7 , 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Increased maternal oxygen demand, elevated diagram, and edema of the respiratory mucosa during pregnancy decrease the maternal tolerance of hypoxia [ 8 ]. Therefore, pregnant women could be more likely to develop a more severe respiratory status (in the case of a viral pneumonia, which happened in the outbreak of H1N1, SARS-CoV-1, and middle east respiratory syndrome coronavirus (MERS-CoV)) [ 1 , 2 , 3 , 7 , 8 , 9 ]. As the course of this disease unfolds, national or international recommendations and guidelines for the prevention and management of SARS-CoV-2 infection in pregnancy are published by various scientific organizations and are constantly updated to correspond to the latest scientific data [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Management and Prevention of COVID-19 in Pregnancy and Pandemic Obstetric Care: A Review of Current Practices

et al. 2021

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Constant accumulation of data results in continuous updates of guidelines and recommendations on the proper management of pregnant women with COVID-19. This study aims to summarize the up-to-date information about the prevention and management of suspected/confirmed SARS-CoV-2 infection in obstetric patients and obstetric care during prenatal, intrapartum, and postpartum periods. We conducted a comprehensive literature search in PubMed for relevant English-written full-text reviews. We also included relevant guidelines and recommendations. In women with a low risk for infection and uncomplicated pregnancy, elective and non-urgent appointments should be postponed or completed through telehealth. Vaccination should be discussed and distance and personal hygiene preventive measures should be recommended. Routine ultrasound examinations should be adjusted in order to minimize exposure to the virus. Standardized criteria should evaluate the need for admission. Women with moderate/high-risk for infection should be isolated and tested with RT-PCR. The mode and timing of delivery should follow routine obstetric indications. In case of infection, glucocorticoids are recommended in critically ill pregnant women, after individualized evaluation. During labor and concomitant infection, the duration of the first two stages should be reduced as possible to decrease aerosolization, while minimization of hemorrhage is essential during the third stage. Close maternal monitoring and adequate oxygenation when necessary always remain a prerequisite. Discharge should be considered on the first or second day postpartum, also depending on delivery mode. Breastfeeding with protective equipment is recommended, as its benefits outweigh the risks of neonatal infection. Recommendations are currently based on limited available data. More original studies on infected pregnant women are needed to establish totally evidence-based protocols of care for these patients.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Management and Prevention of COVID-19 in Pregnancy and Pandemic Obstetric Care: A Review of Current Practices

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“…The only antiviral agents that should be administered during pregnancy are those that are established as safe for pregnant women 11 . Currently, remdesivir can be administered to pregnant women 4 .…”

Section: Discussionmentioning

confidence: 99%

Severe coronavirus disease pneumonia in a pregnant woman at 25 weeks' gestation: A case report

Waratani

Ito

Tanaka

et al. 2021

J of Obstet and Gynaecol

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There are numerous reports on the effects of the coronavirus disease on mothers and fetuses during pregnancy. It is currently unknown whether pregnancy is associated with a high risk of severe coronavirus disease. We report a pregnant patient with coronavirus disease who underwent a cesarean section. A pregnant 39‐year‐old Japanese woman was diagnosed with coronavirus disease at 25 weeks of gestation. Her breathing condition worsened daily, and she required oxygen administration. On day 6 of her 26th week of gestation, she developed severe pneumonia and required tracheal intubation and artificial ventilation, and an emergency cesarean section was performed under general anesthesia. It is necessary to investigate the risk of increased coronavirus disease severity during pregnancy, the effects of coronavirus disease on perinatal prognosis, and the management of pregnancy with coronavirus disease.

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“…SARS-CoV-2, the cause of the rapidly spreading pandemic, affects every population worldwide. Pregnant women are generally more susceptible to infectious diseases due to physiological and mechanical changes in pregnancy [22,23]. Additionally, the physiological T-helper 2 system dominates during pregnancy in favor of the fetus, making the mother more vulnerable to viral infections [23,24].…”

Section: Discussionmentioning

confidence: 99%

Peripartum Covid-19 Pneumonia with Severe ARDS – A Case Report

Maier

Zickler

Metz

et al. 2021

Z Geburtshilfe Neonatol

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Introduction SARS-CoV-2 is a novel coronavirus that was first isolated in Wuhan, China, and resulted in a rapidly spreading pandemic worldwide. Currently there is only limited evidence on the effect of COVID-19 on pregnant women. Case Here we present one of the first serious COVID-19 cases in pregnancy at term with subsequent delivery. Postpartum the mother required antibiotic and symptomatic treatment. She experienced acute worsening of symptoms and developed acute respiratory failure requiring endotracheal intubation and subsequently extracorporeal membrane oxygenation. Conclusion COVID-19 affects all medical disciplines, requiring interdisciplinary approaches and development of patient care regimes. Obstetricians should be aware and be prepared for the special needs of pregnant women with potential prenatal and postnatal issues. Ideally pregnant COVID-19 patients should be cared for at a tertiary perinatal center with experienced perinatologists and neonatologists.

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Covid-19 and Pregnancy: An Overview

Cited by 49 publications

References 54 publications

Management and Prevention of COVID-19 in Pregnancy and Pandemic Obstetric Care: A Review of Current Practices

Management and Prevention of COVID-19 in Pregnancy and Pandemic Obstetric Care: A Review of Current Practices

Severe coronavirus disease pneumonia in a pregnant woman at 25 weeks' gestation: A case report

Peripartum Covid-19 Pneumonia with Severe ARDS – A Case Report

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