COVID-19 and Pediatric Gastroenterology

Taylor, Richard N.; Mallon, Daniel

doi:10.1016/j.pcl.2021.07.003

Cited by 5 publications

(6 citation statements)

References 73 publications

(99 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gastrointestinal symptoms are reported as associated with COVID-19 in pediatric patients. 18,19 Our study is in accordance with these findings, showing that 26.8% of patients admitted to PED with a history of close contact with known COVID-19-positive patients. Taking these observations into account, diarrhea symptoms should be included in those related to a high suspicion of potential SARS-CoV-2 infection, prompting nasopharyngeal PCR collection.…”

Section: Discussionsupporting

confidence: 91%

Comparison Between Pediatric Patients With and Without Close Contact With COVID-19 in a Brazilian City During SARS-CoV-2 Pandemics

Pinto

Helito

Fonseca

et al. 2022

Clin Pediatr (Phila)

View full text Add to dashboard Cite

Objective: To analyze clinical differences between a pediatric population with and without confirmed positive close contact for the new coronavirus, to establish the symptoms that define a population currently served in a children’s emergency room for which polymerase chain reaction (PCR) collection for SARS-COV-2 is performed, and thus, make clinical and laboratory screening more reliable and applicable in medical routine. Method: Cross-sectional study that characterized 128 children (0-17 years old) who collected PCR for SARS-COV-2 when seen in an emergency room at a private hospital between March and June 2020. Data were collected from the electronic medical record of the researched hospital. Results: Patients positive for close contact with COVID-19 had more diarrhea ( P = .03) and less fever ( P = .003) and coughing ( P = .03). There was no statistically significant difference between the 2 groups on gender distribution, age, isolation of other etiologic agents, chest x-ray abnormalities, or the need for hospitalization. SARS-Cov-2 PCR showed a higher positivity among patients on the close contact positive group ( P < .001). Conclusion: As seen in previous research, positive SARS-CoV-2 tests are not required for the pediatric population to be diagnosed with the new coronavirus. Diarrhea should be included in those related to a high suspicion of potential SARS-CoV-2 infection, prompting nasopharyngeal PCR collection. However, fever and cough are unspecific symptoms for SARS-CoV-2 infection and should not be considered as warning signs for parents and, more importantly, for pediatricians to collect screening examinations.

show abstract

Section: Discussionsupporting

confidence: 91%

Comparison Between Pediatric Patients With and Without Close Contact With COVID-19 in a Brazilian City During SARS-CoV-2 Pandemics

Pinto

Helito

Fonseca

et al. 2022

Clin Pediatr (Phila)

View full text Add to dashboard Cite

show abstract

“…Similar to other CLDs, metabolically associated fatty liver disease (MAFLD) has been shown to have longer viral shedding, a higher risk of disease progression, a higher all-cause mortality, and higher COVID-19-related mortality than patients without MAFLD[ 72 , 77 ]. Compared with other causes of CLD, patients with autoimmune hepatitis have a worse prognosis for COVID-19[ 78 , 79 ].…”

Section: Risk Factors For Liver Injurymentioning

confidence: 99%

Liver injury in COVID-19: Clinical features, potential mechanisms, risk factors and clinical treatments

Zhao¹,

Li²,

Li³

et al. 2023

World J Gastroenterol

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) pandemic has been a serious threat to global health for nearly 3 years. In addition to pulmonary complications, liver injury is not uncommon in patients with novel COVID-19. Although the prevalence of liver injury varies widely among COVID-19 patients, its incidence is significantly increased in severe cases. Hence, there is an urgent need to understand liver injury caused by COVID-19. Clinical features of liver injury include detectable liver function abnormalities and liver imaging changes. Liver function tests, computed tomography scans, and ultrasound can help evaluate liver injury. Risk factors for liver injury in patients with COVID-19 include male sex, preexisting liver disease including liver transplantation and chronic liver disease, diabetes, obesity, and hypertension. To date, the mechanism of COVID-19-related liver injury is not fully understood. Its pathophysiological basis can generally be explained by systemic inflammatory response, hypoxic damage, ischemia-reperfusion injury, and drug side effects. In this review, we systematically summarize the existing literature on liver injury caused by COVID-19, including clinical features, underlying mechanisms, and potential risk factors. Finally, we discuss clinical management and provide recommendations for the care of patients with liver injury.

show abstract

“…Pediatrics: Particular populations of children and adolescents may be at greater risk of COVID-19 including those suffering from chronic liver disease. 30 Children presented with gastrointestinal symptoms are found to be at higher risk of the need for pediatric intensive care unit (PICU) admission. 31 Pediatrics are confronted with delays in the presentation of gastrointestinal problems and reduction in endoscopic studies have caused reduced opportunities for clinical and research training.…”

Section: Covid-19 and Gastroenterologymentioning

confidence: 99%

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

Sabetkish

Rahmani

2021

Health Science Reports

View full text Add to dashboard Cite

Background and Aims The Coronavirus disease 2019 (COVID‐19) pandemic globally changed the priorities of medical and surgical procedures. It has caused many healthcare systems to stop performing their routine screenings. Altering medical clinics to COVID‐19 referral centers, lockdowns, and the public fear to refer to medical centers caused a significant reduction in the referral rate; especially in the elderly. This short review article highlights the transform in clinical practice during the post‐COVID era and the need for future medical revolutions. Methods A comprehensive literature search was separately performed by both authors. The articles published between 2019 and August 2021 were included in this study and selected according to a quality appraisal method. Results We have summarized the possible corresponding changes in the diagnosis and treatment of all fields of medical care including internal medicine, surgical, and minor subcategories after the COVID‐19 pandemic. We have also discussed the potential impacts of the pandemic on all these different categories and subcategories of medicine, including the outpatient setting and clinical work. We do believe that the lack of routine check‐ups has led to an increase in the stage of disease in patients with a previously diagnosed problem. On the other hand, the dramatic change in the lifestyle of the population including restricted mobility and increased consumption of unhealthy food has caused metabolic syndrome and other new diseases that have not been diagnosed and properly managed. Conclusion Our findings revealed the urgent need for public health awareness. It indicated the need to carry out both psychological and screening approaches in the post‐COVID era to not miss patients with a chronic disease and new cases who were undiagnosed during the COVID pandemic.

show abstract

COVID-19 and Pediatric Gastroenterology

Cited by 5 publications

References 73 publications

Comparison Between Pediatric Patients With and Without Close Contact With COVID-19 in a Brazilian City During SARS-CoV-2 Pandemics

Comparison Between Pediatric Patients With and Without Close Contact With COVID-19 in a Brazilian City During SARS-CoV-2 Pandemics

Liver injury in COVID-19: Clinical features, potential mechanisms, risk factors and clinical treatments

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

Contact Info

Product

Resources

About