COVID-19 and diabetes: a review literature

Oliveira, Anna Lucy Tavares de; Camilo, Luiz Felipe Lage Souza; Viana, Gilmar Bruno Barros; Braga, Letícia Karoline; Gomes, Cássia Regina Gontijo

doi:10.15406/ipmrj.2020.05.00251

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…44 Stress may also induce the release of stress hormones which trigger liver glycogenolysis, aggravating the effects. 45 Furthermore, SARS-CoV-2 is known to bind to angiotensin-converting enzyme 2 (ACE2) receptors, which are found to be expressed in pancreatic beta-cells, thus rendering it a target for the viral attack. Such binding provides a route for the virus to enter and damage the pancreatic islets, resulting in a defect of insulin production, as indicated in previous study with its SARS virus counterpart.…”

Section: Discussionmentioning

confidence: 99%

High admission blood glucose is an independent risk factor of poor prognosis in COVID-19: A systematic review and dose-response meta-analysis

Lazarus

Audrey

Wangsaputra

et al. 2020

Preprint

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Aims To investigate the prognostic value of admission blood glucose (BG) in predicting COVID-19 outcomes, including poor composite outcomes (mortality/severity), mortality, and severity. Materials and methods Eligible studies evaluating the prognostic value of fasting BG (FBG) and random BG (RBG) levels in predicting COVID-19 outcomes were included and assessed for risk of bias with the Quality in Prognosis Studies tool. Random-effects high-vs-low meta-analysis followed by dose-response analysis using generalized least squares model in a two-stage random-effects meta-analysis were conducted. Potential non-linear association was explored using restricted cubic splines and pooled using restricted maximum likelihood model in a multivariate meta-analysis. Results The search yielded 35 studies involving a total of 14,502 patients. We discovered independent association between admission FBG and poor prognosis in COVID-19 patients. Furthermore, we demonstrated non-linear relationship between admission FBG and severity (Pnon-linearity<0.001), where each 1 mmol/L increase augmented the risk of COVID-19 severity by 33% (risk ratio 1.33 [95% CI: 1.26-1.40]). Albeit exhibiting similar trends, study scarcity limited the strength of evidence on the independent prognostic value of admission RBG. GRADE assessment yielded high-quality evidence for the association between admission FBG and COVID-19 severity, and moderate-quality evidence for its association with mortality and poor outcomes, while the other assessments yielded very low-to-low quality. Conclusion High level of FBG at admission was independently associated with poor prognosis in COVID-19 patients. Further researches to confirm the observed prognostic value of admission RBG and to ascertain the estimated dose-response risk between admission FBG and on COVID-19 severity are required.

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Section: Discussionmentioning

confidence: 99%

High admission blood glucose is an independent risk factor of poor prognosis in COVID-19: A systematic review and dose-response meta-analysis

Lazarus

Audrey

Wangsaputra

et al. 2020

Preprint

View full text Add to dashboard Cite

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High admission blood glucose independently predicts poor prognosis in COVID-19 patients: A systematic review and dose-response meta-analysis

Lazarus

Audrey

Wangsaputra

et al. 2021

Diabetes Research and Clinical Practice

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Highlights Admission fasting blood glucose (AFBG) independently predicts poor COVID-19 outcomes. Risk of COVID-19 severity rises by 33% for each 1 mmol/L increase in AFBG. There is high-quality evidence on the independent link between AFBG and severity. We found moderate-quality evidence linking AFBG with mortality and poor outcomes. Further researches on the independent prognostic value of admission random BG are required.

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A Study to assess the knowledge regarding self management behaviour among Type II Diabetes Mellitus patients in prevention of COVID-19 at selected area, Alappuzha District, Kerala, India

Jain¹,

Clement

2022

AJNER

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A quantitative research study was done to evaluate the effect of planned teaching programme on knowledge regarding self management behaviour among type 2 Diabetes mellitus patients in prevention of Covid-19 at selected areas in Alappuzha district. The objectives were to assess the pretest level of knowledge regarding self management behaviour among type 2 Diabetes mellitus and to find out the association between knowledge regarding regarding self management behaviour among type 2 Diabetes mellitus patients in prevention of covid-19 at selected areas in Alappuzha district with selected demographic variables. The Quantitative research approach was selected with Quasi experimental one group pretest post test control group design. The study was conducted in type 2 Diabetes mellitus patients who have been diagnosed in 5 years at selected areas in Alappuzha district. 50 Samples were selected according to the non-probability convenient sampling techniques. Screening test was done for the population with screening criteria. Knowledge questionnaire was given for 50 type 2 Diabetes mellitus patients who have been diagnosed in 5 year. The study findings reveals that among 50 samples, majority (84%) of the subjects have good knowledge regarding self management behaviour in prevention of COVID 19 remaining 16% percentage have average knowledge and nobody had poor knowledge. The association between knowledge score with various demographic variables shows 0.05 level of significance and it shows there is no significant association between knowledge score and demographic variables like age, sex, religion, type of family, area of residence, education, occupation and income.

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COVID-19 and diabetes: a review literature

Cited by 3 publications

References 27 publications

High admission blood glucose is an independent risk factor of poor prognosis in COVID-19: A systematic review and dose-response meta-analysis

High admission blood glucose is an independent risk factor of poor prognosis in COVID-19: A systematic review and dose-response meta-analysis

High admission blood glucose independently predicts poor prognosis in COVID-19 patients: A systematic review and dose-response meta-analysis

A Study to assess the knowledge regarding self management behaviour among Type II Diabetes Mellitus patients in prevention of COVID-19 at selected area, Alappuzha District, Kerala, India

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