COVID‐19 and COVID‐19 vaccine‐related dermatological reactions: An interesting case series with a narrative review of the potential critical and non‐critical mucocutaneous adverse effects related to virus, therapy, and the vaccination

Abstract

This narrative review article was conducted to lay out a summarized but exhaustive review of current literature over mucocutaneous manifestations in 4 dimensions of SARS‐CoV‐2 pandemic: virus itself, treatment‐related, vaccine‐induced, and alteration of chronic dermatologic diseases following infection. Virus and vaccine‐related were mainly self‐limited and non‐severe. Treatment‐related reactions could be life‐threatening.

Immune thrombocytopenic purpura secondary to COVID‐19 vaccination: A systematic review

“…EVANS syndrome was also observed in one case. 27,30,36,37 Regarding the constitutional symptoms, we noticed a higher prevalence of fever, headache and a lower occurrence of fatigue, compared to primary ITP. 36 Lastly, while no mortality has ever been reported for MMR vaccine-associated ITP, we had a single case of fatality in our data.…”

“…Only four patients sustained ICH, all had received mRNA‐based vaccines and one led to a fatal outcome despite aggressive immunosuppressive therapy and craniotomy. Like COVID‐19 infection‐induced ITP, EVANS syndrome was also observed in one case 27,30,36,37 …”

Constrictive pericarditis following inactivated virus COVID-19 vaccine: a case report with review of the literature

“…Eventually, it merits emphasizing that, nevertheless, our patient encountered a serious adverse event of COVID-19 vaccination; given the rarity of these reactions, vaccination benefits still outweigh, and the vaccine is known as the best weapon to overcome the global burden of COVID-19 pandemic [13] , [14] , [15] , [16] .…”

Concurrent COVID-19 and pneumocystis carinii pneumonia in a patient subsequently found to have underlying hairy cell leukemia

“…COVID-19 infection solitarily has myriad manifestations and complications which can make its diagnosis challenging and this challenge will be more difficult when co-infection occurs or there is an underlying disease that can affect the COVID-19 infection disease course [ 7 , 8 ]. PCP infection in a COVID-19-infected patient occurred either in the context of immunosuppression due to HIV infection or using long-term immunosuppressives like high-dose corticosteroids but we reported the SARS-CoV-2 and PCP infection in an individual with a background of HCL which is for the first time to the best of our knowledge [ 9 ].…”