COVID-19: An Emerging Culprit of Inflammatory Arthritis

Mukarram, Muhammad Shariq; Ghauri, Muhammad Ishaq; Sethar, Sehrish; Afsar, Nasir Ali; Riaz, Amir; Ishaq, Khizra

doi:10.1155/2021/6610340

Cited by 28 publications

(31 citation statements)

References 23 publications

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“…It is a heterogeneous disease with a duality of inflammation and autoimmunity, leading to the production of autoantibodies and serving as a trigger for inflammatory and autoimmune arthritis such as systemic lupus erythematosus. 2 , 3 There are multiple case reports of spondyloarthritis-related reactive arthritis following COVID-19 infection with resolution following cessation of inflammatory response. 4 – 11 …”

Section: Discussionmentioning

confidence: 99%

COVID-19-induced psoriatic arthritis: a case report

Essien

Chastant

McNulty

et al. 2022

Therapeutic Advances in Chronic Disease

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Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which may lead to uncontrolled immune activation and cytokine response in some. The pattern of pro-inflammatory cytokines is similar to that which has been observed to be involved in rheumatic diseases and target treatments. Viral arthritis is common with a wide variety in spectrum ranging from arthralgia to spurious and chronic arthritis. However, recent studies have demonstrated a correlation with endemic coronaviruses and increased risk of developing rheumatoid arthritis (RA). Cases are being identified that describe a post-COVID reactive; however, to date, no report has been published describing the onset of psoriasis and concomitant development of psoriatic arthritis after COVID-19 infection. We report an interesting case of psoriatic arthritis in a post-COVID-19 infection patient with review of the current literature.

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Section: Discussionmentioning

confidence: 99%

COVID-19-induced psoriatic arthritis: a case report

Essien

Chastant

McNulty

et al. 2022

Therapeutic Advances in Chronic Disease

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“…One common complication has been reported in inflammatory reactive arthritis based on the hypothesis of the proinflammatory markers (IL-6 and TNF- α ) being released in alveolar and musculoskeletal inflammation [ 61 ]. Similar to RA, one common post-COVID-19 complication is an early onset of arthritis that can be cured by non-steroidal anti-inflammatory drugs.…”

Section: Orthopedic Conditions and Covid-19mentioning

confidence: 99%

Connections between Orthopedic Conditions and Oxidative Stress: Current Perspective and the Possible Relevance of Other Factors, Such as Metabolic Implications, Antibiotic Resistance, and COVID-19

et al. 2022

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The general opinion in the literature is that these topics remain clearly understudied and underrated, with many unknown aspects and with controversial results in the respective areas of research. Based on the previous experience of our groups regarding such matters investigated separately, here we attempt a short overview upon their links. Thus, we summarize here the current state of knowledge regarding the connections between oxidative stress and: (a) orthopedic conditions; (b) COVID-19. We also present the reciprocal interferences among them. Oxidative stress is, of course, an interesting and continuously growing area, but what exactly is the impact of COVID-19 in orthopedic patients? In the current paper we also approached some theories on how oxidative stress, metabolism involvement, and even antibiotic resistance might be influenced by either orthopedic conditions or COVID-19. These manifestations could be relevant and of great interest in the context of this current global health threat; therefore, we summarize the current knowledge and/or the lack of sufficient evidence to support the interactions between these conditions.

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“…Mukarram et al reported five patients who developed inflammatory arthritis following COVID-19 infection. All patients developed polyarthritis showing symmetrical distribution, including large and small (distal and proximal interphalangeal) joints, with musculoskeletal ultrasound scans showing evidence of symmetrical synovitis [10]. Ghauri et al described a case of a 34-year-old male who developed reactive arthritis (right knee) 10 days after being diagnosed with COVID-19 [11].…”

Section: Post-covid-19 Inflammatory Arthritismentioning

confidence: 99%

Case Report of a Saga of Post-COVID-19 Complications

Kamath¹,

Sharma²,

Laik³

et al. 2021

Cureus

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Coronavirus disease 2019 , caused by severe acute respiratory syndrome coronavirus 2, is characterized by symptoms such as fever, sore throat, cough, fatigue, myalgias, headache, diarrhea, and dysgeusia. In a majority of the cases, it causes mild illness. However, in severe cases, the virus activates the immune system causing systemic inflammation, immune dysregulation, and pro-thrombotic state leading to various complications. Among hospitalized patients with COVID-19, pneumonia, sepsis, and respiratory failure are frequent complications. However, even in the second year of the COVID-19 pandemic, our knowledge of its myriad clinical features and complications is still incomplete and continues to evolve. Here, we present the case of a patient who developed several complications post-COVID-19 one after the other. He was admitted with severe COVID-19 for which he received standard COVID-19 treatment and mechanical ventilation. In the post-COVID-19 state extending up to six months, he serially developed deep vein thrombosis, endogenous endophthalmitis, empyema, and post-inflammatory arthritis of the hip joints. To our knowledge, such a case has not been reported earlier in the literature.

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COVID-19: An Emerging Culprit of Inflammatory Arthritis

Cited by 28 publications

References 23 publications

COVID-19-induced psoriatic arthritis: a case report

COVID-19-induced psoriatic arthritis: a case report

Connections between Orthopedic Conditions and Oxidative Stress: Current Perspective and the Possible Relevance of Other Factors, Such as Metabolic Implications, Antibiotic Resistance, and COVID-19

Case Report of a Saga of Post-COVID-19 Complications

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