Cover Picture: Science is multidimensional and very complex. – Eur. J. Immunol. 9/2008

Abstract

The cover image was specifically designed based on an illustration provided by Minguet et al., the authors of Enhanced B‐cell activation mediated by TLR4 and BCR crosstalk (pp. 2475–2487). The authors demonstrate that while simultaneous stimulation of TLR4 and BCR activates B cells in an additive manner, antigen‐coupled LPS activates B cells synergistically. The authors proposed this image based on the idea that “science is multidimensional and will never be finished or completely understood”. The illustration was further enhanced with images taken from various studies published in this issue of the European Journal of Immunology.