Cover Picture: Ir‐Catalyzed Intramolecular Cyclization of 2‐Alkynyl Diaryl Sulfides for the Selective Synthesis of Sulfur‐Containing Polycyclic Compounds (Adv. Synth. Catal. 20/2022)

Abstract

The inside cover picture illustrates that starting from 2‐alkynyl diaryl sulfides, intramolecular cyclization realized selective construction of sulfur‐containing five to seven‐membered systems by the choice of reaction temperature and aryl group using the same iridium catalysis. When 2‐alkynylphenyl “naphthyl” sulfides were used, triaryl‐fused thiepines possessing a 7‐membered ring were obtained at 100 °C. The reaction of 2‐alkynyl diaryl sulfides at 120 °C gave 9‐arylidene‐9H‐thioxanthenes with 6‐membered system. The reaction of 2‐alkynylphenyl “naphthyl” sulfides at 160 °C afforded diaryl‐substituted benzothiophene with 5‐membered system. Details can be found in the communication by Takanori Shibata and co‐workers (T. Shibata, T. Iwaki, M. Ito, Adv. Synth. Catal. 2022, 364, 3472–3476; DOI: 10.1002/adsc.202200565).