Cover Picture: Intracellular Modulation of Excited‐State Dynamics in a Chromophore Dyad: Differential Enhancement of Photocytotoxicity Targeting Cancer Cells (Angew. Chem. Int. Ed. 18/2015)

Abstract

Orthogonal BODIPY dimers offer exciting potential as activatable photosensitizers for photodynamic therapy. In their Communication on J. Yoon, E. U. Akkaya et al. report a photosensitizer that is switched on by a reaction with glutathione (GSH). Comparative cell culture data show that the agent is preferentially activated in cancer cells as they feature a higher glutathione level than normal cells.