Covalently Grafted 4-Aminopyridine-Reduced Graphene Oxide-Modified Screen-Printed Carbon Electrode for Electrochemical Sensing of Lead Ions

Gunasekaran, Balu Mahendran; Rajendran, Ganesh Kumar; Rayappan, John Bosco Balaguru; Sivanesan, Jothi Ramalingam; Nesakumar, Noel; Paulraj, Ajit Walter

doi:10.1007/s13369-023-07829-2

Cited by 3 publications

(1 citation statement)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The screen-printed carbon electrode (SPCE) is a useful technology that has been widely used in the practical application of biosensors oriented toward point-of-care testing (POCT) [1][2][3][4][5][6][7]. Many researchers have reported on electrochemical biosensors that use SPCE to detect hormones [8][9][10], ions [11,12], metals [13], nucleic acid [14][15][16][17][18][19], and proteins [20][21][22][23]. Although the sensitivity of the electrochemical biosensor is controlled by surface conditions, such as the diffusion coefficient and electron transfer rate [24], these are altered by the modification of molecular recognition elements and blocking materials on the electrode surface.…”

Section: Introductionmentioning

confidence: 99%

Surface Modification of Screen-Printed Carbon Electrode through Oxygen Plasma to Enhance Biosensor Sensitivity

Osaki,

Saito,

Nagai

et al. 2024

Biosensors

View full text Add to dashboard Cite

The screen-printed carbon electrode (SPCE) is a useful technology that has been widely used in the practical application of biosensors oriented to point-of-care testing (POCT) due to its characteristics of cost-effectiveness, disposability, miniaturization, wide potential window, and simple electrode design. Compared with gold or platinum electrodes, surface modification is difficult because the carbon surface is chemically or physically stable. Oxygen plasma (O2) can easily produce carboxyl groups on the carbon surface, which act as scaffolds for covalent bonds. However, the effect of O2-plasma treatment on electrode performance remains to be investigated from an electrochemical perspective, and sensor performance can be improved by clarifying the surface conditions of plasma-treated biosensors. In this research, we compared antibody modification by plasma treatment and physical adsorption, using our novel immunosensor based on gold nanoparticles (AuNPs). Consequently, the O2-plasma treatment produced carboxyl groups on the electrode surface that changed the electrochemical properties owing to electrostatic interactions. In this study, we compared the following four cases of SPCE modification: O2-plasma-treated electrode/covalent-bonded antibody (a); O2-plasma-treated electrode/physical adsorbed antibody (b); bare electrode/covalent-bonded antibody (c); and bare electrode/physical absorbed antibody (d). The limits of detection (LOD) were 0.50 ng/mL (a), 9.7 ng/mL (b), 0.54 ng/mL (c), and 1.2 ng/mL (d). The slopes of the linear response range were 0.039, 0.029, 0.014, and 0.022. The LOD of (a) was 2.4 times higher than the conventional condition (d), The slope of (a) showed higher sensitivity than other cases (b~d). This is because the plasma treatment generated many carboxyl groups and increased the number of antibody adsorption sites. In summary, the O2-plasma treatment was found to modify the electrode surface conditions and improve the amount of antibody modifications. In the future, O2-plasma treatment could be used as a simple method for modifying various molecular recognition elements on printed carbon electrodes.

show abstract

Section: Introductionmentioning

confidence: 99%

Surface Modification of Screen-Printed Carbon Electrode through Oxygen Plasma to Enhance Biosensor Sensitivity

Osaki,

Saito,

Nagai

et al. 2024

Biosensors

View full text Add to dashboard Cite

show abstract

Covalently incorporated heterocyclic benzotriazole-reduced graphene oxide as a High-Performance electrochemical supercapacitor electrode

Srinivasan,

Muthiah,

Rajendran

et al. 2024

Materials Science and Engineering: B

View full text Add to dashboard Cite

Review—Graphene-Based Electrochemical Sensors for Detecting Environmental Pollutants

Harini,

Ponraj

2024

J. Electrochem. Soc.

View full text Add to dashboard Cite

In this population driven society, the major causes of environmental pollution are modern agricultural practices and intensified industrialization. These kind of economic practices lead to excessive deposition of residual pesticides and heavy metals in both soil and water. Due to their quicker advancement in in-situ and point-of-care technologies, electrochemical sensing methods have chosen as best for detecting these contaminants. ‘Graphene’, a wonder material possessing excellent physiochemical properties when utilized as an electrode for sensing, enables quicker diffusion of target analytes. Graphene-based nanocomposites, when used as a working electrodes, allow for detection of environmental contaminants even at trace levels. Presently, scientists are working to develop an electrochemical sensor which facilitates accuracy and high sensitivity. This review highlights the performance of graphene composites in detecting various environmental pollutants using electrochemical sensing strategies. Further, comparative study on its methods and techniques, existing problems with some solutions and future aspects are briefly discussed.

show abstract

Covalently Grafted 4-Aminopyridine-Reduced Graphene Oxide-Modified Screen-Printed Carbon Electrode for Electrochemical Sensing of Lead Ions

Cited by 3 publications

References 47 publications

Surface Modification of Screen-Printed Carbon Electrode through Oxygen Plasma to Enhance Biosensor Sensitivity

Surface Modification of Screen-Printed Carbon Electrode through Oxygen Plasma to Enhance Biosensor Sensitivity

Covalently incorporated heterocyclic benzotriazole-reduced graphene oxide as a High-Performance electrochemical supercapacitor electrode

Review—Graphene-Based Electrochemical Sensors for Detecting Environmental Pollutants

Contact Info

Product

Resources

About