Coupling between a calix[6]arene-based chromatography column and ICP-MS for on-line actinide analysis

Abstract

Analysis of actinides by coupling a calix[6]arene column to a Q-ICP-MS for emergency situations.

An isotope dilution mass spectrometry overview: tips and applications for the measurement of radionuclides

“…ICP-MS is widely used for actinide (U, Pu, Am) analyses of biological samples 241,246,247,249–270 with calibration methods that rely on an actinide isotope that is absent from the sample, such as 233 U for U isotopes ( 234 U, 235 U, 236 U and 238 U), 242 Pu for Pu isotopes ( 239 Pu, 240 Pu, and 241 Pu) or 243 Am for 241 Am analysis. Ni et al .…”

Operational Protocol for Detection of Contamination by Actinides U, Pu and Am in Urine Using Calixarene Columns: From Mineralization to ICP-MS Measurement

“…These results show that this separation protocol based on calixarene columns allows to improve detection limits by a factor 150 for U isotopes and The coupling between the calixarene column and the ICP-MS for on-line detection could be a way to improve detection limits [12]. With new developments in Table 7.…”

“…The combination of two columns was suggested, the hydroxamic calix [6]arene column for the Pu isolation followed by the carboxylic calix [6]arene column for the U/Am separation with an elution step by EDTA. Lastly, a method based on the coupling of the hydroxamic calix [6]arene column to a quadrupole ICP-MS for on-line actinide analysis was developed [12]. In this method, the calixarene column is used for the precon-centration of actinides, whereas the ICP-MS allows the separation of actinides and their on-line detection.…”