In this paper, rigid antimicrobial polymeric nanocomposites were developed-polymeric material based on chemically functionalized nanoparticles with polydimethylsiloxane (PDMS)-dispersed in a plastomer matrix. By dispersing them in plastomer matrix (polyvinyl chloride-PVC), hybrid TiO 2 /ZnO nanoparticles (50:50) (fillers) functionalized for good compatibility have led to the development of an advanced polymeric material with antibacterial, multifunctional and processing properties specific to plastics. Experimental polymeric materials are adapted to biomedical and food applications, therefore, they were tested for stability and long-term antimicrobial activity. The combined effects of functionalised nanoparticles and polymer on the structure and properties of new experimental materials were studied. Experimental nanocomposites were morpho-structurally, microbiologically and physico-mechanically characterized. KEY WORDS: nanocomposite, antibacterial, functionalized, rigid COMPOZIT POLIMERIC RIGID ANTIMICROBIAN ÎN MATRICE DE PVC ŞI NANOPARTICULE DE ZnO ŞI TiO 2 FUNCŢIONALIZATE REZUMAT. În această lucrare s-au realizat nanocompozite polimerice antimicrobiene rigide-material polimeric bazat pe nanoparticule funcţionalizate chimic cu polidimetil siloxan (PDMS)-dispersate într-o matrice de plastomer. Prin dispersarea lor în matrice de plastomer (clorură de polivinil-PVC), nanoparticulele hibride TiO 2 /ZnO (50:50) (materiale de umplere) funcţionalizate pentru o bună compatibilizare au condus la obţinerea unui material polimeric avansat cu caracteristici antibacteriene, multifuncţionale şi proprietăţi de prelucrare specifice materialelor plastice. Materialele polimerice experimentate sunt adaptate aplicaţiilor biomedicale şi alimentare, prin urmare, au fost testate din punct de vedere al stabilităţii şi activităţii antimicrobiene pe termen lung. Au fost studiate efectele combinate ale nanoparticulelor funcţionalizate şi ale polimerului asupra structurii şi proprietăţilor materialelor noi experimentate. Nanocompozitele experimentate au fost caracterizate morfo-structural, microbiologic şi fizico-mecanic. CUVINTE CHEIE: nanocompozite, antibacterian, funcţionalizat, rigid COMPOSITE POLYMÉRIQUE ANTIMICROBIEN RIGIDE EN PVC ET NANOPARTICULES DE ZnO ET TiO 2 FONCTIONNALISÉES RÉSUMÉ. Dans cet article, on a développé des nanocomposites polymères antimicrobiennes rigides-matériau polymérique à base de nanoparticules chimiquement fonctionnalisées avec du polydiméthylsiloxane (PDMS)-dispersés dans une matrice de plastomère. En les dispersant dans une matrice de plastomère (polychlorure de vinyle-PVC), les nanoparticules hybrides de TiO 2 /ZnO (50:50) fonctionnalisées pour une bonne compatibilité ont conduit au développement d'un matériau polymère avancé doté de propriétés antibactériennes, multifonctionnelles et propriétés de traitement spécifiques aux plastiques. Les matériaux polymères expérimentaux sont adaptés aux applications biomédicales et alimentaires. Ils ont donc été testés pour déterminer leur stabilité et leur activité ...