“…In recent years, some methods are developed for this purpose. They include Seurat (Butler et al, 2018;Stuart et al, 2019), MOFA (Argelaguet et al, 2018), coupleNMF (Duren et al, 2018), scVDMC (Zhang et al, 2018), LIGER (Welch et al, 2019), scACE (Lin et al, 2019), MOFA+ (Argelaguet et al, 2020), scAI (Jin et al, 2020), coupleCoC (Zeng and Lin, 2020) and scMC (Zhang and Nie, 2021). A more comprehensive discussion on integration of single-cell genomic data is presented in David et al (2020).…”