Coulometric Analysis Experiment for the Undergraduate Chemistry Laboratory

Abstract

facilitated expedient analysis of the samples. Students were able to directly apply Faraday's laws of electrolysis and mole relationships to the household product analysis. The PDMS cell can be used for other electrochemical experiments as well.' ASSOCIATED CONTENT b S Supporting Information Directions to make the miniature PDMS coulometry cell; detailed experimental procedure and calculations. This material is available via the Internet at http://pubs.acs.org.

Electrochemical Quantification of Acetaminophen: An Engaging Cyclic Voltammetry Laboratory for the Quantitative Analysis Course

“…Electrochemistry is an important topic in undergraduate chemistry programs, , but students may find the subject difficult and subsequently lose interest in it. The laboratory portion of the quantitative analysis course often includes experiments such as redox and conductometric titrations, and it could include the electrochemical analysis of several substances, including natural and pharmaceutical compounds such as ascorbic acid, iron supplements, and acetaminophen (APAP). , The quantification of APAP has been explored in undergraduate laboratories by several techniques such as colorimetry, spectrophotometry, − and in complex samples by 1 H NMR and liquid chromatography. , Measuring APAP content in over-the-counter medications is important due to how frequently it is used as an analgesic and antipyretic drug, and given the APAP toxicity, since at higher dosages becomes hepatotoxic and genotoxic, the correct concentration of APAP in the medication is of paramount importance. − The relevance of this analysis is also highlighted by the recent reports on the development of specific and stable electrodes for the electrochemical sensing of APAP with possible applications in pharmaceutical quality control. , …”

“…Electrochemistry is an important topic in undergraduate chemistry programs, 1,2 but students may find the subject difficult and subsequently lose interest in it. The laboratory portion of the quantitative analysis course often includes experiments such as redox and conductometric titrations, and it could include the electrochemical analysis of several substances, including natural 3 and pharmaceutical compounds such as ascorbic acid, 4 iron supplements, 5 and acetaminophen (APAP). 6,7 The quantification of APAP has been explored in undergraduate laboratories by several techniques such as colorimetry, 8 spectrophotometry, 9−11 and in complex samples by 1 H NMR 12 and liquid chromatography.…”

An Integrated Database of Common Chemicals and Chemistry Demonstrations and Student Experiments Used in Hungary

“…The free molecular iodine concentration (I 2 ) is only 4.5 × 10 –6 mol/L (1.1 ppm) in 20% solution, the maximum (∼10 –4 mol/L, 25.4 ppm) is reached in 0.1% solution . As in many chemical demonstration experiments iodine is used in solution, we supposed that this complex can substitute iodine in several situations that are beyond the traditional use of the povidone–iodine complex. − …”

Iodine Coulometry of Various Reducing Agents Including Thiols with Online Photocell Detection Coupled to a Multifunctional Chemical Analysis Station To Eliminate Student End Point Detection by Eye

“…Starch is used as the visual indicator when iodine is the electrogenerated titrant. 1,3,4,8,9 Twin polarized electrodes for biamperometric measurements have been used for cyclohexene, hydrazine, biologically active thiols, and carbimazole determina-tions. 6,7,10,11 Some authors have used two or more different end point determination methods to compare their precision.…”